Clinical trials: Intramedullary Nail
Subtalar Arthritis, Ankle Arthritis
Compression Nail for Tibiocalcaneal Arthrodesis
The purpose of this study is to determine the clinical efficacy of a novel dynamic compression intramedullary nail for tibiotalocalcaneal (TTC) arthrodesis
- Trial name
- NCT03780452
- Testing
- novel dynamic compression intramedullary nail
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Alabama at Birmingham
Distal Femoral Fractures, Extra-articular Distal Radius Malunions
Retrograde Nail vs Double Plating for Distal Femoral Extra and Simple Articular Fractures With Metaphyseal Comminution
The objective of this study is to compare the short term functional clinical and radiological outcomes of retrograde nail versus double plating for distal femoral extra-articular and simple articular fractures with metaphyseal…
- Conditions
- Distal Femoral Fractures, Extra-articular Distal Radius Malunions, Intramedullary
- Trial name
- NCT07542249
- Testing
- Retrograde nail, Double plating
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Fracture
Treatment of Unstable Both-Bone Midshaft Forearm Fractures in Children
The investigators created a randomized clinical trial between 1 or 2 elastic stable intramedullary nails to find out what kind of treatment is optimal for unstable both-bone midshaft forearm fractures.
- Trial name
- NCT00314587
- Testing
- 1 or 2 elastic stable intramedullary nails
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colaris, Joost, M.D.
Tibial Shaft Fractures
Carbon Fiber Implants
The investigators will compare intramedullary nailing of open and closed tibia shaft fractures with carbon fiber implant versus titanium implant in a Level I trauma setting.
- Trial name
- NCT03382041
- Testing
- Carbon Fiber Implant, Titanium Implant
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Femur Fracture, Osteotomy
ZNN Bactiguard Antegrade Femoral Nails PMCF Study
This is a multicenter, prospective, Post-market Clinical Follow-up (PMCF) Study on the ZNN Bactiguard Antegrade Femoral Nails. The objective of this study is to collect data confirming the safety, performance, and clinical…
- Trial name
- NCT05339360
- Testing
- Femoral fixation with intramedullary nails
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Osteoarthritis of the Knee, Arthroplasty, Replacement, Knee
Flex Intramedullary Rod Study
The purpose of this study is to compare the effect of post-operative ROM between Flex IM rod and Rigid IM rod, to collect bone morphology of Japanese lower extremity and to research the incidence of overhung with Flex IM rod.
- Trial name
- NCT02543489
- Testing
- Flex IM rod
- Where
- 3 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Stryker Japan K.K.
Osteoarthritis, Varus Malalignment
Ellipse Intramedullary High Tibial Osteotomy Nail Study
The purpose of this study is to collect outcomes data in patients implanted with the Ellipse IM HTO Nail System.
- Trial name
- NCT02519218
- Testing
- Ellipse Technologies Intramedullary High Tibial Osteotomy Nail System
- Volunteers
- 6 people
- Sponsor
- Ellipse Technologies, Inc.
Foot Arthritis
Use of a Sustained Dynamic Compression Intramedullary Nail for Subtalar Arthrodesis
The purpose of this study is to determine the clinical efficacy of a novel dynamic sustained compression intramedullary nail for subtalar (talocalcaneal) arthrodesis.
- Trial name
- NCT04784156
- Testing
- Subtalar (Talocalcaneal) Arthrodesis, DynaNail Mini
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MedShape, Inc
Tibial Fractures, Fracture Infection
Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study
Primary objective of this study is to compare fracture related infection (FRI) rates of ZNN Bactiguard Tibia to conventional uncoated titanium-alloy nails 12 months after tibia fracture fixation.
- Trial name
- NCT05022485
- Testing
- ZNN Bactiguard tibia
- Where
- 16 sites in Austria, France and 6 more
- Volunteers
- 500 people
- Sponsor
- Zimmer Biomet
Intertrochanteric Femur Fractures
Computer-Assisted Navigation for Intramedullary Nail Fixation of Intertrochanteric Femur Fractures
There are approximately 250,000 hip fractures in the US every year, and intertrochanteric (IT) fractures (fractures that occur just below the femoral head) account for nearly half of these fractures.
- Trial name
- NCT02190435
- Testing
- Stryker ADAPT computer-assisted navigation, Conventional technique
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Corewell Health East
Femoral Neck Fractures, Intertrochanteric Fracture
Re-Evaluation of GAmma3 Intramedullary Nails in Hip Fracture (REGAIN)
The purpose of this study is to assess the impact of Gamma3 intramedullary nails versus sliding hip screws on rate of revision surgery in individuals with inter-trochanteric fractures.
- Trial name
- REGAIN (NCT00555945)
- Testing
- Gamma3 intramedullary nail (Stryker), Sliding Hip Screw
- Where
- 5 sites in Canada, Denmark and 1 more
- Volunteers
- 90 people
- Sponsor
- Stryker Trauma and Extremities
Tibial Fracture
Tibial IMN Vs. Tibial Micromotion IMN
Our null hypothesis is that micromotion tibial intramedullary fixation (IMFN) does not impact union or complication rates when compared to standard of care treatment with non-micromotion tibial nail fixation.
- Trial name
- NCT06976801
- Testing
- Intramedullary tibial Nail, Intermedullary nail
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- University of Chicago
Diaphyseal Femur Fracture
Comparative Study Between Operative and Non-Operative Management of Femoral Shaft Fractures in Children
The goal of this clinical trial was to compare the management of pediatric femoral shaft fractures using either Thomas splint traction or Elastic Stable Intramedullary Nailing (ESIN).
- Trial name
- ESIN-THOMAS (NCT07483944)
- Testing
- Thomas splint, ESIN (Elastic Stable Intramedullary Nails)
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Femoral Fractures
A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
This study looks at two (2) types of surgical treatments and hopes to answer the question, "which is the best way to surgically treat a distal femur fracture?" Both procedures being studied are standard of care (used routinely)…
- Trial name
- NCT00429663
- Testing
- reamed, interlocking intramedullary nail, locking periarticular plate
- Where
- 22 sites in United States
- Volunteers
- 160 people
- Sponsor
- Boston Medical Center
Fractures, Bone, Impending Fracture
Retrospective Study on Clinical Performance and Safety Profile of Agile Nail
This study aims to retrospectively collect data from routine clinical practice in order to evaluate the safety profile of the Agile intramedullary nail, used in pediatric patients according to the manufacturer Instructions For…
- Conditions
- Fractures, Bone, Impending Fracture, Deformity; Bone
- Trial name
- Agile (NCT06412939)
- Testing
- Agile Nail
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Orthofix s.r.l.
Hip Fracture, Anemia
Study of the Effect of Tranexamic Acid Administered to Patients With Hip Fractures. Can Blood Loss be Reduced?
The effect of Tranexamic acid on blood loss, hemoglobin and transfusions in patients with pertrochanteric hip fractures. Tranexamic acid is a well known drug used in many types of surgery.
- Trial name
- NCT01535781
- Testing
- Tranexamic Acid
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Hvidovre University Hospital
Hip Fractures
Long vs Extended-short Nail When Treating Proximal Femur Fractures
Fractures of the upper part of the femur may be treated with intramedullary nails. There are different designs to choose from. The intention of this RCT is to compare two nails with some of the same properties, but with different…
- Trial name
- NCT04652310
- Testing
- TFNA extended-short nail (235 mm), TFNA long nail (260-480mm)
- Where
- 2 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Vestre Viken Hospital Trust
Tibial Fracture
SPRINT - Randomized Trial of Tibial Fracture Fixation
The purpose of this study is to determine if there is a difference in the rate of healing of a tibia fracture treated with an intramedullary nail based on whether or not the bone was reamed prior to nail insertion.
- Trial name
- NCT00038129
- Testing
- Intramedullary nail implant
- Where
- 16 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of Minnesota
Humerus Fracture, Femur Fracture
Evaluation of Handling and Possible Complications Related to the Newly Developed Angular Stable Locking System (ASLS)
In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. Due to the play between screw and nail, the reduction can be lost and the instability can result in malunions…
- Conditions
- Humerus Fracture, Femur Fracture, Tibia Fracture
- Trial name
- ASLS-Pre (NCT00793637)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 30 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Intertrochanteric Fractures
The Effect of Loss of Offset After Pertrochanteric Fracture Treated With a Intramedullary Nail
The purpose of this study is determine the relationship between pain and protrusion of the implant after surgery for a intertrochanteric fracture.
- Trial name
- PLAIN (NCT01344785)
- Testing
- Intramedullary nailing
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital