Clinical trials: Intramedullary Nail
Fracture Healing
Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing
The primary objective of this study is to investigate the effect of romosozumab compared with placebo on time to radiographic healing of fresh tibial diaphyseal fractures (fractures in the midsection of the shinbone).
- Trial name
- STARTT (NCT00907296)
- Testing
- Romosozumab
- Where
- 103 sites in United States, Australia and 21 more
- Volunteers
- 402 people
- Sponsor
- Amgen
Femoral Fractures
Nails Versus Plates for Femur Fractures in Dar es Salaam, Tanzania
This is a prospective observational study of patients with femur fractures in Dar es Salaam, Tanzania comparing two different surgical techniques: intramedullary nailing (IMN) and open reduction internal fixation (ORIF) with a…
- Trial name
- NCT01548456
- Testing
- Intramedullary Nailing, Open Reduction Internal Fixation
- Where
- Tanzania
- Volunteers
- 332 people
- Sponsor
- University of California, San Francisco
Fracture of Clavicle
Post Treatment Comparison Intramedullary Nail vs. Nonoperative Treatment
The objective of this post-market clinical study is to compare one to three year post treatment results, range of motion, strength, patient related functional outcomes and patient satisfaction, of internal fixation using the…
- Trial name
- NCT01975467
- Testing
- CRx
- Where
- 2 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sonoma Orthopedic Products, Inc.
Fracture Femur, Fracture Tibia
Standard Versus Short Course Prophylactic Antibiotic in Femur and Tibia Shaft Fractures Managed With Intramedullary Interlocking Nail
Long-bone fractures, particularly of femur and tibia, are common following fall injury and road traffic accidents.1,2 The standard treatment is "intramedullary nailing," where a metal rod is inserted into the center of the bone…
- Conditions
- Fracture Femur, Fracture Tibia, Surgical Site Infection (SSI), Antibiotic
- Trial name
- NCT07554079
- Testing
- Short Course Antibiotics, Standard Course Antibiotics
- Where
- Nepal
- Volunteers
- 56 people
- Sponsor
- Kathmandu University School of Medical Sciences
Open Fracture Tibia
Evaluate Clinical and Radiological Outcomes After Limb Reconstruction Using Monorail Fixator Over Intramedullary Nailing in Tibial Open Fractures With Bone Loss
Road traffic accidents (RTA) is the most common cause of open fractures of long bones, increase in RTA leading to increase of complex non-unions incidence.
- Trial name
- NCT05296785
- Testing
- intramedullary nail with Limb Reconstruction System
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Shaft Femure Fracture in Adolescents
Fixation of Shaft Femure Fracrture by Ender Versus Plate
The aim of this study is to compare the functional outcomes, fracture healing time, rate of complications, and long-term growth outcomes between intramedullary nail and plating in adolescent.
- Trial name
- NCT07067333
- Testing
- intramedullary nails for group A, plate for group B
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Fractures, Bone
"Bio-logical" Carbon Fiber Intramedullary Nail Biomechanical Test and Preliminary Clinical Results
The aim of this study is to present a novel Intramedullary Nail (IMN) made of CFR - PEED composite, that is biomechanically tailored to closely match cortical bone.
- Trial name
- NCT01815658
- Testing
- Carbon fiber intramedullary nail (PEEK-CF)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Hip Fracture
Short Versus Standard Intramedullary Nail for Trochanteric Hip Fractures
In England each year over 65,000 people fracture their hip. Most of these patients are elderly females with the fracture occurring after a simple trip or stumble.
- Trial name
- NCT02680028
- Testing
- targon pft nail
- Where
- United Kingdom
- Volunteers
- 229 people
- Sponsor
- Peterborough and Stamford Hospitals NHS Foundation Trust
Ankle Arthritis, Foot Arthritis
Use of a Dynamic Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis
The purpose of this study is to determine the clinical efficacy of a novel dynamic compression intramedullary nail for tibiotalocalcaneal (TTC) arthrodesis.
- Trial name
- NCT03747952
- Testing
- Tibiotalocalcaneal arthrodesis, DynaNail
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- MedShape, Inc
Tibial Fractures
Study Evaluating InductOs in Diaphyseal Tibia Fractures
Demonstrate a larger proportion of subjects with healed fractures among subjects treated with InductOs and reamed, locked intramedullary nailing compared to subjects treated with reamed, locked intramedullary nailing alone.
- Trial name
- NCT00161616
- Testing
- InductOs
- Where
- 27 sites in Belgium, Finland and 10 more
- Volunteers
- 277 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Proximal Humerus Fractures
Randomised Study Between Intramedullary Locking Nails and Locking Plates for Treatment of Proximal Humerus Fractures
Primary purpose of this study was to compare functional outcomes after displaced and proximal humerus fracture between nails and locked plates.
- Trial name
- HUMERUS (NCT01557413)
- Testing
- Intramedullary nail, Locked plate
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bone Metastases, Pathological Fracture
Short Versus Long Intramedullary Nails in the Treatment of Proximal Femur Metastasis.
The goal of this interventional randomized controlled trial is to compare the clinical outcomes in treating extremities pathological fractures (fractures of limbs caused by metastatic tumors) or impending pathological fractures…
- Conditions
- Bone Metastases, Pathological Fracture, Pathological Fracture, Left Femur, Pathological Fracture, Right Femur
- Trial name
- NCT05969470
- Testing
- Internal fixation with short intramedullary nails, Internal fixation with long intramedullary nails
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Open tíbia Fracture
Open Tibia Fractures a Comparative Study Between Biplane External Fixator and Locked Intramedullary Nail
The objective of this research is to prospectively evaluate a group of patients with shaft compound fracture of the tibia, treated with a biplanar external fixator or locked intramedullary reamed nail.
- Trial name
- NCT02064595
- Testing
- External fixator, Intramedullary nail
- Volunteers
- 68 people
- Sponsor
- Fabio lucas rodrigues
Leg Length Inequality
Study to Assess the Pain, Satisfaction, and Quality of Life of Patients With FITBONE® Lengthening Nail
This study is a prospective observational non-interventional multi-centre cohort study of patients, 12 years or older, initiating a lower limb lengthening procedure with FITBONE and who have a length discrepancy of 30mm or more…
- Trial name
- FitForFrance (NCT06156384)
- Testing
- FITBONE® Lengthening Nail
- Where
- 6 sites in France, Reunion
- Volunteers
- 45 people
- Sponsor
- Orthofix s.r.l.
Shoulder Fractures, Intramedullary
Operative Treatment of 2-fragment-fractures (AO 11-A3) of the Proximal Humerus in the Elderly: Cement Augmented Locking Plate Philos vs. Proximal Humerus Nail MultiLoc
Proximal humeral fractures are with an incidence of 4-5% the third most common fractures in the elderly. Compared to fractures of the upper limb it is the second most common fracture after distal radial fractures.
- Conditions
- Shoulder Fractures, Intramedullary, Bone Plates
- Trial name
- NCT02609906
- Testing
- PhilosTM with augmentation (Depuy-Synthes), MultiLoc®-Nail (Depuy-Synthes)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Femur Fracture
Post-operative Anemia in Lateral Fractures of the Femur.
It was conducted a prospective study with a series of 45 patients with lateral fragility fractures of the femur treated by three different intramedullary nails.
- Trial name
- NCT05225753
- Testing
- hemoglobin serum value
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Tibial Fractures
Compartmental Overpressures Associated to Reamed Intramedullary Nails
The purpose of this study is to determine the effect of reamed intramedullary nails in tibial shaft fractures (as a standard treatment), in raising intracompartmental pressures and therefore determine if they are a risk factor…
- Trial name
- NCT00842101
- Testing
- Quick Pressure Monitor
- Where
- Andorra
- Volunteers
- 80 people
- Sponsor
- University of Andorra
Wrist Fracture
WRx Distal Radius Wrist Fracture Study
This research project is a multi-year proposal, with the goals of answering and evaluating the following: 1. Does an intramedullary locking device applied in an extra-articular distal radius fracture improve post operative pain…
- Trial name
- NCT01293227
- Testing
- Surgical treatment of distal radius fractures
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Subtrochanteric Nonunion
Bone Graft in Aseptic Subtrochanteric Nonunion
This study aimed to compare the radiologic results between closed nailing without bone graft (BG) and open nailing with BG for subtrochanteric nonunion and to determine when open BG should be considered.
- Trial name
- NCT04651647
- Testing
- Revision surgery with / without open bone graft
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Jae Hoon Jang
Femoral Fracture, Children
Modification of ESIN-osteosynthesis in a Femoral Fracture Model and Its Transmission to Clinical Practice
Elastic stable intramedullary nailing (ESIN) is the standard treatment for displaced diaphyseal femoral fractures in children. However, some literature report high complication rates (10-50%) in complex fractures.
- Trial name
- ESIN (NCT01673048)
- Testing
- 3-Nail-ESIN in femoral shaft fractures
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Luebeck