Clinical trials: Intraocular Lens Implantation
To Collect Information About Visual Outcomes and Participant Satisfaction
Prospective Evaluation of Visual Outcomes With Tecnis One-Piece Multifocal Intraocular Lenses Compared With Patients Previously Implanted With Crystalens Aspheric Optic (AO)
The study is being conducted to collect information about visual outcomes and participant satisfaction with the Tecnis One-Piece Multifocal (MF) Intraocular Lenses (IOLs) compared with participants previously implanted with…
- Trial name
- NCT01191229
- Testing
- Tecnis one-piece MF IOL, Crystalens AO
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Vision Disorders
Modification in Cortical Activation in Pseudophakic Patients With Visual Difficulties After a Multifocal Implantation
This study will highlight differences in cortical activation between asymptomatic and symptomatic patients.
- Trial name
- PlainteIMF (NCT02529098)
- Testing
- fMRI
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Intraocular Lens Replacement
Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
The purpose of this study is to determine the safety and efficacy of OMS302 (the study drug) for maintaining intraoperative mydriasis in individuals undergoing Intraocular Lens Replacement (ILR) surgery.
- Trial name
- OMS302-ILR-003 (NCT01454063)
- Testing
- OMS302
- Where
- 16 sites in United States
- Volunteers
- 405 people
- Sponsor
- Omeros Corporation
Intraocular Lens
Comparison of Quality of Vision After Bifocal and Extended Depth of Focus Intraocular Lens Implantation
To compare the visual performance of the extended depth of focus (EDOF) intraocular lens (IOL) to bifocal and spherical monofocal IOL
- Trial name
- NCT04557579
- Testing
- Clear corneal phacoemulsification and IOL implantation
- Where
- Taiwan
- Volunteers
- 97 people
- Sponsor
- Taipei Nobel Eye Clinic
Pseudophakia
The Effects of Angle Kappa on Clinical Outcomes With the PanOptix Intraocular Lens
Angle Kappa is considered a potential factor in explaining suboptimal outcomes with intraocular lenses (IOLs), particularly multifocal IOLs. Some evidence suggests this is not the case.
- Trial name
- NCT04242875
- Testing
- Angle Kappa, Visual disturbance questionnaire.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract Senile
Performance of Two Intraocular Lenses With Extended Depth of Vision
Comparison of the capsular bag performance of two extended depth of vision (EDOF) intraocular lenses (IOLs), the Rayone EMV and the Alcon Acrysof IQ Vivity, in a mini-monovision setting
- Trial name
- NCT05194150
- Testing
- non-diffractive monofocal IOL, standard EDOF IOL
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract
Visual Outcomes of Vivity in Patients With High Axial Length
The objective is to assess the visual outcomes and quality of vision of patients receiving the AcrySof® Vivity Intraocular lens (IOL), when implanted in eyes with high ocular axial length (≥24.5mm), after uneventful cataract…
- Trial name
- NCT05210569
- Testing
- Vivity
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Dr. James J. Wiens Medical Corporation
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Senile Cataract
Safety and Efficacy of Implantation of Two Multifocal Intraocular Lenses in the Treatment of Senile Cataract
This trial is designed to compare the biocompatibility and long-term visual outcomes of the Tecnis Z9001 and Acri.LISA 366D multifocal IOLs used for the treatment of senile cataract.
- Trial name
- NCT02966496
- Testing
- Acri.LISA366D multifocal aspheric IOLs, TecnisZ9001 multifocal aspheric IOLs
- Volunteers
- 40 people
- Sponsor
- Qinghai University
Cataract, Pseudoexfoliation Syndrome
Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery
To evaluate long-term intraocular lens (IOL) decentration and tilt in eyes with pseudoexfoliation syndrome (PES) following cataract surgery using Visante anterior segment OCT and iTrace Visual Function Analyzer.
- Conditions
- Cataract, Pseudoexfoliation Syndrome, Pseudophakia
- Trial name
- NCT03453827
- Testing
- no intervention
- Volunteers
- 37 people
- Sponsor
- Hospital Hietzing
Cataract, Intraocular Lens Complication
In-vivo Behavior of Asqelio Monofocal Biaspheric Intraocular Lens
This is a study to evaluate the 24 month postoperative incidence and intensity of posterior capsular opacity in patients submitted to cataract surgery and implanted with a hydrophobic monofocal IOL.
- Trial name
- NCT04971863
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- AST Products, Inc.
To Study the Influence of an Multifocal Intraocular Lens With Different Addition on Intermediate Visual Acuity
Visual Performance of New Apodized Diffractive Multifocal IOL With Addition of Plus Three
The purpose of the study is to determine whether implantation of a multifocal IOL with a modified addition at lens plane(Restor +3) results in better intermediate visual acuity with similar performance at distance and near…
- Trial name
- NCT01027533
- Testing
- Implantation of a multifocal Intraocular lens
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Visual Acuity
Post-Market Study of Alcon Intraocular Lenses
The purpose of the study is to evaluate clinical and functional performance in real-world conditions in participants who have been implanted with Acrysof IQ Vivity (Extended Vision) IOLs compared with Alcon Aspheric Monofocal…
- Trial name
- NCT05414565
- Testing
- Vivity IOL, Aspheric monofocal IOL
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract, Lens Opacity
Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707)
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacity, Presbyopia
- Trial name
- NCT03688399
- Testing
- IOL implantation experimental, IOL implantation comparator
- Where
- Hungary
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Rotational Stability of the TECNIS Eyhance Toric
Evaluation of the rotational stability of a new toric intraocular lens (IOL), the TECNIS Eyhance toric II.
- Trial name
- NCT05126368
- Testing
- Cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Intraocular Lens, Cataract
Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling
During cataract surgery an artificial intraocular lens (IOL) is implanted in the eye to replace the lens and to correct the refraction for distance vision. Misalignment of IOLs can cause severe loss of visual quality.
- Trial name
- Tilt (NCT06305338)
- Testing
- Optical Coherence Tomography
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Johannes Kepler University of Linz
Dislocated Intraocular Lens
Modification of Scleral Suture Fixation of Dislocated IOL
A prospective randomized study on patients with late in the bag intraocular lens (IOL) dislocation after cataract surgery. Two surgical techniques of suturing of IOL to the sclera will be compared in the study.
- Trial name
- NCT04150263
- Testing
- Intraocular lens (IOL) ab externo scleral suture fixation, Modified IOL ab externo scleral suture fixation
- Where
- Sweden
- Volunteers
- 117 people
- Sponsor
- St. Erik Eye Hospital
Presbyopia
Clinical Performance of a Phakic Intraocular Lens (IOL)
This study will evaluate the clinical performance of a phakic intraocular lens (IOL) for the improvement of Uncorrected Near Visual Acuity (UCNVA) in subjects who require between +1.00 and +2.50 Reading Add.
- Trial name
- NCT03499821
- Testing
- EDOF ICL
- Where
- 6 sites in Belgium, Spain
- Volunteers
- 41 people
- Sponsor
- Staar Surgical Company
Cataract Senile
Precisight® Intraocular Lens Implantation for Cataract Treatment
The purpose of this study is to determine the refractive outcomes and optimize the clinical features of a new intraocular lens intended to treat the senile cataract.
- Trial name
- PEACE (NCT02970487)
- Testing
- Intraocular implant of the Precisight
- Where
- Philippines
- Volunteers
- 96 people
- Sponsor
- InfiniteVision Optics
Presbyopia, Pseudophakia
Identification of Minimum Focal Points in Vision Curve Formation
The primary objective of this study is to identify how many focal points and at which distances are necessary for reliable visual curve formation and area of the curve (AoC) calculation using mathematical models and comparing the…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06260852
- Testing
- Diagnostic Test: Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace