Clinical trials: Intraocular Lens Opacification
Cataract Complicated, Cataract Complications Operations
Performance of Two Sclera Fixated Intraocular Lens Concepts
To evaluate and compare the post-operative outcome of two different sceral fixated IOL concepts, the Yamane method (ZA9003, J\&J, USA) and the Carlevale IOL (FIL-SSF, Soleko, Italy).
- Trial name
- Carlevale (NCT05779306)
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- Austria
- Volunteers
- 26 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Postoperative Complications
Validation of an Artificial Intelligence System for Postoperative Management of Cataract Patients
Cataract surgery is the current standard of management for cataract patients, which is typically succeeded by a postoperative follow-up schedule.
- Conditions
- Cataract, Postoperative Complications, Artificial Intelligence
- Trial name
- NCT04138771
- Testing
- An artificial intelligence system for postoperative management of cataract patients
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Cataract
Influence of Two Different Preloaded Intraocular Lens (IOLs) on Posterior Capsule Opacification
Studies showed that a sharp posterior optic edge of an intraocular lens (IOL) inhibits migration of lens epithelial cells in between posterior capsule and optic of the IOL and therefore reduces the rate of posterior capsule…
- Trial name
- NCT00673803
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Hospital Hietzing
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two IOLs: Hoya iMics Y-60H vs. Bausch&Lomb MI60 (MIMI)
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- NCT01786356
- Testing
- HOYA iMics Y-60H, B&L MI60
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Uveitis, Cataract
Outcome of Different IOLs in Patients With and Without Uveitis
Cataract, is a clouding of the lens in the eye gradually leading to reduction of the visual acuity. In most cases it can be managed with surgery, removing the own lens and replacing it with an artificial lens, intraocular lens…
- Conditions
- Uveitis, Cataract, Inflammation, Posterior Capsule Opacification
- Trial name
- NCT02975895
- Testing
- Hydrophobic IOL: Vivinex (HOYA), Hydrophilic IOL: INCISE (Bausch+Lomb)
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Vastra Gotaland Region
Posterior Capsule Opacification
Posterior Capsule Opacification and Optical Quality of Different Hydrophobic Acrylic Intraocular Lenses
The most frequent long-term complication of cataract surgery remains to be posterior capsule opacification (PCO). During the past decades many new intraocular lenses (IOL) with optimized lens material and design were introduced.
- Trial name
- NCT03831074
- Testing
- Implantation of an intraocular lenses: iMics 1 NY-60 & NY-60G
- Sponsor
- Medical University of Vienna
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification Development With Two Different Intraocular Lenses
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- MIPHY (NCT01734343)
- Testing
- HOYA iMics Y-60H, PhysIOL microAY
- Where
- Austria
- Volunteers
- 65 people
- Sponsor
- Medical University of Vienna
Posterior Capsule Opacification, Postoperative Complications
Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery
This prospective, randomized, clinical trial looks to compare children undergoing congenital cataract surgery with intraocular lens (IOL) implantation in terms of visual axis obscuration as well as postoperative complications…
- Trial name
- NCT02491918
- Testing
- cataract surgery, Intraocular lens implantation
- Volunteers
- 61 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Posterior Capsule Opacification, Pseudophakia
IOL Position and Refractive Change After Nd:YAG Laser Posterior Capsulotomy
After cataract surgery, the thin natural membrane that holds the artificial lens in place can slowly turn cloudy. This is called posterior capsule opacification. It makes vision blurry and can cause glare.
- Conditions
- Posterior Capsule Opacification, Pseudophakia, Refractive Errors
- Trial name
- YAG-IOL-POS (NCT07802145)
- Testing
- Nd:YAG laser posterior capsulotomy, Anterior segment swept-source OCT, Swept-source optical biometry
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Vienna Hospital Association
Posterior Capsule Opacification
Posterior Capsule Opacification (PCO) With Single Piece Hydrophobic Versus Hydrophillic Intraocular Lens (IOL)
The purpose of the study was to compare the postoperative PCO results of the single-piece hydrophobic Acrylic IOLs versus the newer generation single-piece hydrophilic Acrylic IOLs in patients undergoing bilateral cataract…
- Trial name
- NCT01125345
- Testing
- Phacoemulsification
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract After, Astigmatism
Influence of Residual Astigmatism on Visual Acuity in Patients Undergoing Cataract Surgery With Trifocal Intraocular Lens Implantation
MAIN OBJECTIVE: To assess the influence of residual astigmatism on visual acuity in the different lens foci in patients operated on for cataracts with a trifocal intraocular lens implant.
- Conditions
- Cataract After, Astigmatism, IOL, Visual Acuity
- Trial name
- NCT04387721
- Testing
- Kind of trifocal IOL
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Enrique Ordiñaga-Monreal, OD, MSc
Macular Holes, Intraocular Lens Opacification
Oral Sedation in Vitreoretinal Surgery
The purpose of this study is to compare the efficacy of oral sedation to intravenous sedation with anesthesiology support and monitoring.
- Conditions
- Macular Holes, Intraocular Lens Opacification, Vitrectomy, Vitreous Hemorrhage
- Trial name
- NCT04346095
- Testing
- Oral Sedatives with or Without Analgesia, Intravenous Sedatives with or Without Analgesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rocky Vista University, LLC
Cataract, Pseudophakia
Retrospective, Non-interventional, Comparative Clinical Investigation of the Safety and Performance of 690AD and 690ADY Monofocal Intraocular Lens Implantation With Extended Patient Enrolment
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOLs) are indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Conditions
- Cataract, Pseudophakia, Intraocular Lens Complication, Intraocular Lens Opacification
- Trial name
- NCT06578923
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- 2 sites in Hungary
- Volunteers
- 51 people
- Sponsor
- Medicontur Medical Engineering Ltd
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.
Assessing DEXTENZA efficacy when placed within the upper eyelid canaliculus as opposed to the lower eyelid canaliculus.
- Trial name
- NCT04592081
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kerry Assil, MD
Posterior Capsule Opacification
Quantification of Posterior Capsule Opacification in Pediatric Cataract
The purpose of this study is to quantify the opacity of posterior capsule in pediatric cataract comparing two intraocular lens materials.
- Trial name
- Cataract (NCT02968290)
- Testing
- Cataract Surgery, Alcon AcrySof SA60AT, Bausch Lomb AkreosA
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Intraocular Lens Complication
Capsular Tension Ring With Hydeophilic Intraocular Lesnes to Decrease Posterior Capsule Opacification Versus Hydrophobic Ones
evaluate the clinical outcomes of routine CTR insertion in conjunction with hydrophilic versus hydrophobic IOLs following phacoemulsification.
- Trial name
- NCT06974578
- Testing
- phacoemulsification, CTR, hydrophilic IOL
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Cataract, Intraocular Lens Opacification
Posterior Capsular Opacification and Glistenings in Hydrophobic and Hydrophilic Intraocular Lenses
A prospective randomized controlled clinical study to measure posterior capsular opacification, objective measurement of glistenings and intraocular lens tilt and decentration as well as visual outcomes following insertion of a…
- Trial name
- NCT04122664
- Testing
- RayOne® Hydrophobic lens 800C, RayOne® Hydrophilic lens 600C
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cataract, Pseudophakia
Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification
Purpose: To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Clariflex silicone intraocular lens (IOL) with that of the double-round edge design of the SI40…
- Trial name
- NCT00428363
- Testing
- Cataract surgery with implantation of an intraocular lens
- Where
- Austria
- Volunteers
- 52 people
- Sponsor
- Medical University of Vienna
Cataract, Pseudophakia
Clinical Investigation of the Safety and Performance of Model 690AD and Model 690ADY Monofocal Intraocular Lens Implantation
Medicontur hydrophilic posterior chamber monofocal intraocular lens (IOLs) are indicated to improve vision at far distance in adults with cataract and/or ametropia (hyperopia, myopia), secondarily to removal of the crystalline…
- Conditions
- Cataract, Pseudophakia, Intraocular Lens Complication, Intraocular Lens Opacification
- Trial name
- NCT05750225
- Testing
- Standard of care, Patient satisfaction questionnare
- Where
- 2 sites in Hungary
- Volunteers
- 52 people
- Sponsor
- Medicontur Medical Engineering Ltd
Capsule Opacification, Ocular Hypertension
Prophylactic Use of Timolol Maleate to Prevent Intraocular Pressure Elevation After Nd:YAG Laser Posterior Capsulotomy
This randomized controlled trial evaluated whether a single drop of 0.5% timolol maleate, administered before neodymium-doped yttrium aluminium garnet (Nd:YAG) laser posterior capsulotomy, reduced the rise in intraocular pressure…
- Trial name
- NCT07729189
- Testing
- Timolol Maleate, No intervention
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- CMH Multan Institute of Medical Sciences