Clinical trials: Intraocular Lens Replacement
Intraocular Lens Replacement, Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome Undergoing Intraocular Lens Replacement Surgery
The purpose of this study is to evaluate the effect of OMS302 on the signs of Intraoperative Floppy Iris Syndrome in patients at risk.
- Trial name
- NCT02093689
- Testing
- Part 1 OMS302, Part 2 OMS302
- Where
- 2 sites in Austria, Germany
- Volunteers
- 18 people
- Sponsor
- Omeros Corporation
Cataracts
Selection of Aspheric Diffractive Multifocal Intraocular Lens (IOLS) Based on Corneal Wavefront
Given the availability of aspheric diffractive IOLs with varying negative spherical aberration it may be feasible, by selecting the best fit IOL, to minimize aberrations and thereby maximize visual performance.
- Trial name
- NCT00999492
- Testing
- Tecnis® Multifocal (TMF)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mark Packer, MD, FACS
Cataract
A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
The goal of this clinical trial is to learn if MELT-300 works on procedural sedation in adult participants undergoing cataract extraction with lens replacement (CELR). It will also learn about the safety of MELT-300.
- Trial name
- NCT06383273
- Testing
- MELT-300 sublingual tablet, Midalozam sublingual tablet
- Where
- 12 sites in United States
- Volunteers
- 528 people
- Sponsor
- Melt Pharmaceuticals
Cataract Extraction
Exploratory Study of OMS302 Injection in Subjects Undergoing Unilateral Cataract Extraction by Phacoemulsification.
This is an exploratory study to determine the safety and clinical benefit of OMS302 Injection in subjects undergoing Cataract Extraction with Lens Replacement (CELR) using a coaxial phacoemulsification process.
- Trial name
- NCT00721695
- Testing
- OMS302, OMS302-PE, Vehicle
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Omeros Corporation
Cataract
Post-Implant Performance of the EC-3 IOL
The purpose of this study is to obtain data on the performance of the EC-3 lens at an interval of two years (and beyond) from subjects who were implanted.
- Trial name
- NCT01333345
- Where
- 3 sites in United States, France
- Volunteers
- 100 people
- Sponsor
- Aaren Scientific Inc.
Cataract
ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL)
Randomized, parallel group, subject masked, multi-center six (6) month follow-up study comparing ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power IOL Model SN6AD1 implanted in both eyes to ACRYSOF® ReSTOR® Aspheric +4.0 D Add Power IOL…
- Trial name
- NCT00684138
- Testing
- ACRYSOF® ReSTOR® Aspheric +4.0 D Add Power Intraocular Lens, ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Alcon Research
Intraocular Lens Replacement
Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
The purpose of this study is to determine the safety and efficacy of OMS302 (the study drug) for maintaining intraoperative mydriasis in individuals undergoing Intraocular Lens Replacement (ILR) surgery.
- Trial name
- OMS302-ILR-003 (NCT01454063)
- Testing
- OMS302
- Where
- 16 sites in United States
- Volunteers
- 405 people
- Sponsor
- Omeros Corporation
Intraocular Lens Replacement
Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
The purpose of this study is to determine the safety, efficacy and pharmacokinetics of OMS302 (the study drug) for maintaining intraoperative mydriasis and preventing post operative pain in individuals undergoing Intraocular Lens…
- Trial name
- OMS302-ILR-004 (NCT01579565)
- Testing
- OMS302
- Where
- 14 sites in United States, Netherlands
- Volunteers
- 416 people
- Sponsor
- Omeros Corporation
Cataract
A Study of MELT-300 (Midazolam and Ketamine Sublingual Tablets) for Sedation and Intraoperative Ocular Analgesia in Participants Undergoing Cataract Extraction With Lens Replacement (CELR)
The primary purpose of the study is to evaluate the efficacy and safety of MELT-300 (Midazolam and Ketamine Sublingual Tablets) and the contribution of midazolam and ketamine components to sedation and during the surgery or…
- Trial name
- NCT05133518
- Testing
- MELT-300, Midazolam alone, Ketamine alone
- Where
- 3 sites in United States
- Volunteers
- 338 people
- Sponsor
- Melt Pharmaceuticals