Clinical trials: Intraocular Lenses
Inflammation, Cataract
A Real-world Study of DEXYCU in the Treatment of Inflammation After Cataract Surgery
This is a prospective, real-world study aimed to evaluate the efficacy and safety of Dexycu in treating postoperative inflammation of cataracts.
- Trial name
- NCT06497699
- Testing
- Dexycu
- Where
- 2 sites in China
- Volunteers
- 263 people
- Sponsor
- Ocumension Therapeutics (Shanghai) Co., Ltd
Cataract
A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.
This is a prospective, multi-center, masked, three-arm, randomized clinical study of the TECNIS Eyhance Toric II IOL (test #1) and TECNIS Synergy Toric II (test #2) compared to the TECNIS Toric 1-Piece IOL (control).
- Trial name
- NCT05396599
- Testing
- Model DIU, Model DFW, Model ZCT
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataracts
A Real-World Study for the TECNIS Synergy™ Intraocular Lens
This is a prospective and retrospective, single-center, single-arm, open-label clinical study of the TECNIS Synergy™ IOL. The study will enroll up to 100 subjects from a single site in China.
- Trial name
- NCT05090826
- Testing
- Model ZFR00V
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Vision Performance Evaluation of TECNIS EYHANCE™ With TECNIS SIMPLICITY™ Compared to TECNIS® 1-piece Intraocular Lenses
This study is a 6-month, prospective, multicenter, bilateral, randomized subject- and evaluator-masked, clinical investigation of the TECNIS Eyhance IOL versus the TECNIS 1-piece IOL.
- Trial name
- NCT05025345
- Testing
- Tecnis Eyhance, Tecnis 1 piece IOL
- Where
- 15 sites in United States
- Volunteers
- 228 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Clinical Investigation of a New Intraocular Lens
The purpose of this clinical trial is to evaluate the safety and effectiveness of the TECNIS Symfony Extended Range of Vision IOL.
- Trial name
- NCT02203721
- Testing
- TECNIS Symfony Extended Range of Vision IOL, Model ZXR00, TECNIS Monofocal IOL, Model ZCB00
- Where
- 15 sites in United States
- Volunteers
- 324 people
- Sponsor
- Abbott Medical Optics
Cataract
Clinical Investigation of the Next-Generation Intraocular Lenses
This study is a 6-month, prospective, multicenter, subject/evaluator-masked, bilateral, randomized clinical investigation of the TECNIS Next-Generation Model ZFR00 and Model ZYR00 IOLs versus the TECNIS Multifocal Model ZLB00…
- Trial name
- NCT03372434
- Testing
- Investigational Intraocular Lens Device #1: Model ZFR00, Investigational Intraocular Lens Device #1: Model ZYR00, TECNIS Multifocal Intraocular Lens: Model ZLB00
- Where
- 12 sites in United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Lens Opacities
Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort
The planned clinical investigation will be conducted to acquire raw data for the development of the algorithm. The data acquisition is intended to obtain first impressions of the potential performance of the changed hardware and…
- Conditions
- Cataract, Lens Opacities, Artificial Lens Implant, Corneal Astigmatism
- Trial name
- BioBase (NCT05458661)
- Testing
- Clinical Prototype BioBase (SN 07 and SN 08)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Aphakia, Cataract
Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT03895034
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- RxSight, Inc.
Cataract
Comparison of Gemini III Rev 2 Implanted in Conjunction With an Approved IOL vs Eyes Implanted With an Approved IOL
This study is a prospective, observational, randomized, controlled, paired eye, subject-masked design.
- Trial name
- NCT04059796
- Testing
- Omega Gemini III Rev 2 Device, Control Eye
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Cataract, Lens Opacities
Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Prospective, randomised, controlled, single-surgeon, single-center post-market clinical follow up study to compare the clinical outcomes of two trifocal IOLs with different material
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1702 (NCT03347981)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
Comparison of ISOPURE and EYHANCE (Switzerland)
This is a prospective randomised open-label study with the aim to compare the visual performance of the premium monofocal Isopure IOL versus the extended depth of focus Eyhance® IOL after phaco-emulsification cataract surgery.
- Trial name
- PHY2301 (NCT05875922)
- Testing
- IOL implantation experimental (ISOPURE 1.2.3.), IOL implantation active comparator (TECNIS Eyhance)
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract Senile
Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)
Extended depth of focus (EDF) intraocular lens (IOL) versus Monofocal intraocular lens (IOL)
- Trial name
- NCT07092020
- Testing
- EDF, Monofocal IOL
- Where
- 14 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 220 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Glaucoma
Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution
This trial is a randomized study to evaluate and compare two doses of the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- Tigris (NCT06120842)
- Testing
- Bimatoprost Implant System (High Dose), Bimatoprost Implant System (Low Dose), Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataract, Lens Opacities
Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL
Prospective, controlled, single-surgeon, single-center post-market clinical follow up study to investigate the clinical outcomes of a hydrophobic trifocal IOL (PhysIOL POD F GF)
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1703 (NCT03306342)
- Testing
- IOL implantation experimental
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Astigmatism, Far Sightedness
Clinical Results of a Monofocal Aspheric Bitoric Intraocular Lens With Plate Haptics in Hyperopic Eyes (HIPER-AT-TORBI)
Observational post-marketing study with prospective follow-up of CE marked medical devices aimed at the treatment of hyperopia and astigmatism in patients with cataract.
- Conditions
- Astigmatism, Far Sightedness, Cataracts
- Trial name
- HIPER-AT-TORBI (NCT05058274)
- Testing
- Implant of the AT-TORBI 709 lens
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- OFTALVIST (Oftalmología Vistahermosa S.L)
Cataract
To Compare Early Rotation of Two Extended Depth of Focus Intraocular Lenses
To demonstrate that the Carl Zeiss Meditec (CZM) Extended depth of focus (EDOF) Intraocular lens (IOL) is superior to the competitor EDOF IOL with respect to Rotational Stability.
- Trial name
- VENUStoric (NCT03839420)
- Testing
- CZM IOL, Competitor IOL
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Presbyopia
IOL Implantation After KAMRA Inlay Removal
A. The primary purpose of the study is to evaluate outcomes of aphakic eyes implanted with the IC-8 IOL following cataract removal in prior inlay patients after KAMRA inlay removal. B.
- Trial name
- NCT03320473
- Testing
- IC-8 IOL
- Where
- Philippines
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Cataract
Functional Vision With ACRYSOF® IQ IOLs Blue Light Filtration
The purpose of this study is to compare the reaction time (as measured by braking reaction time in seconds during simulated driving) under glare and no-glare conditions in subjects implanted with ACRYSOF® IQ intraocular lenses…
- Trial name
- NCT02219997
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses, ACRYSOF® IQ IOL
- Volunteers
- 90 people
- Sponsor
- Alcon Research
Primary Open Angle Glaucoma
24h Continuous Intraocular Pressure (IOP) Monitoring vs Goldmann Applanation Tonometry
A study in which intraocular pressure (IOP) will be monitored over 24 hours using the SENSIMED Triggerfish® device and Goldmann applanation tonometry (GAT) in primary open angle glaucoma patients.
- Trial name
- NCT01217853
- Testing
- SENSIMED Triggerfish
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Sensimed AG
Cataract
Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).
Randomized contralateral clinical trial with single piece (Model SN60WF) vs. three piece (Model MA60AC) AcrySof Intraocular Lenses (IOLs) on development of Posterior Chamber Opacifiation (PCO).
- Trial name
- NCT00758745
- Testing
- Model SN60WF, Model MA60AC
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Alcon Research