Clinical trials: Intraocular Lenses
Age-Related Macular Degeneration, Lens, Intraocular
Implantation of SML in Patients With Dry Age-related Macular Degeneration and Myopic Maculopathy
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in developed countries among people over 50 years of age. Myopic maculopathy is also an important cause of irreversible vision loss.
- Conditions
- Age-Related Macular Degeneration, Lens, Intraocular, Myopic Maculopathy
- Trial name
- NCT03882606
- Testing
- Scharioth Macula Lens (SML, Medicontur)
- Where
- Spain
- Volunteers
- 3 people
- Sponsor
- Consorci Sanitari de Terrassa
Refractive Errors, Myopia
Correlation Between Preoperative Refraction and Anterior Segment Parameters With ICL Vault
This prospective non-comparative interventional study aims to analyse the pre-operative factors affecting the range of optimal ICL vaulting.
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism
- Trial name
- NCT05670626
- Testing
- Refractive Surgery
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Astigmatism, Far Sightedness
Clinical Results of a Monofocal Aspheric Bitoric Intraocular Lens With Plate Haptics in Hyperopic Eyes (HIPER-AT-TORBI)
Observational post-marketing study with prospective follow-up of CE marked medical devices aimed at the treatment of hyperopia and astigmatism in patients with cataract.
- Conditions
- Astigmatism, Far Sightedness, Cataracts
- Trial name
- HIPER-AT-TORBI (NCT05058274)
- Testing
- Implant of the AT-TORBI 709 lens
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- OFTALVIST (Oftalmología Vistahermosa S.L)
Cataract, Keratoconic Subjects
Visual Outcomes and Quality of Life After Vivity EDOF IOL Implantation in Early-Stage Keratoconus
The goal of this clinical trial is to learn if the Vivity Extended Depth of Focus intraocular lens works to improve vision in adults with cataracts and early-stage keratoconus.
- Trial name
- VIVITY-KCONUS (NCT07338708)
- Testing
- Extended Depth of Focus Intraocular Lens Implantation
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Capsule Opacification, Ocular Hypertension
Prophylactic Use of Timolol Maleate to Prevent Intraocular Pressure Elevation After Nd:YAG Laser Posterior Capsulotomy
This randomized controlled trial evaluated whether a single drop of 0.5% timolol maleate, administered before neodymium-doped yttrium aluminium garnet (Nd:YAG) laser posterior capsulotomy, reduced the rise in intraocular pressure…
- Trial name
- NCT07729189
- Testing
- Timolol Maleate, No intervention
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Age- Related Macular Degeneration, Diabetic Retinopathy
A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics Analysis
This project systematically investigates the role of the intraocular microbiome in various ocular diseases, including age-related macular degeneration, diabetic retinopathy, and cataracts.
- Conditions
- Age- Related Macular Degeneration, Diabetic Retinopathy, Retinal Vein Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT07897513
- Testing
- Not applicable- observational study
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Cataract
Prediction of Pseudophakodonesis of Intraocular Lenses
Compare visual acuity of patients after cataract surgery with implantation of an IOL clinical outcome measure in eyes with and without pseudoexfoliation syndrome or history of ocular trauma.
- Trial name
- NCT03751462
- Testing
- Purkinjemeter
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Congenital Cataract
Comparison of the Effect of Minimal Invasive Lens Surgery and Traditional Cataract Surgery
Previously, the investigators have developed a minimal invasive lens surgery in the purpose of reduce post-operative complications of congenital cataract.
- Trial name
- NCT03908359
- Testing
- traditional cataract surgery, minimal invasive lens surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Cataract
To Compare Early Rotation of Two Extended Depth of Focus Intraocular Lenses
To demonstrate that the Carl Zeiss Meditec (CZM) Extended depth of focus (EDOF) Intraocular lens (IOL) is superior to the competitor EDOF IOL with respect to Rotational Stability.
- Trial name
- VENUStoric (NCT03839420)
- Testing
- CZM IOL, Competitor IOL
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Neural Compensation, Visual Function and Visual Quality After Monofocal or Multifocal Intraocular Lens Implantation
Multifocal intraocular lenses (MIOLs) provide enhanced far and near visual acuity, but they can bring about halos and glare, which are caused by design deficiencies of the IOLs.
- Trial name
- NCT02644720
- Testing
- multifocal intraocular lens implantation, monofocal intraocular lens implantation, Dexamethasone
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Cataract
Trifocal Intraocular Lens (IOL) Aberrometry Outcomes
The goal of this study is to evaluate subject outcomes and spectacle independence with intraoperative aberrometry and trifocal IOL implantation.
- Trial name
- NCT04196569
- Testing
- Alcon Trifocal and Trifocal Toric Intraocular Lenses
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
Cataract and IOL Surgery, Keratoplasty
Postoperative Outcomes of a Toric AddOn Intraocular Lens After Keratoplasty and Cataract Surgery
The aim of this clinical study is to evaluate a toric add-on intraocular lens (IOL) for the correction of high astigmatism in patients who have undergone keratoplasty and cataract surgery.
- Conditions
- Cataract and IOL Surgery, Keratoplasty, Toric Intraocular Lens Stability
- Trial name
- AddOn (NCT07452042)
- Testing
- AddOn toric IOL implantation
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Cataract, Presbyopia
IOL Implantation After KAMRA Inlay Removal
A. The primary purpose of the study is to evaluate outcomes of aphakic eyes implanted with the IC-8 IOL following cataract removal in prior inlay patients after KAMRA inlay removal. B.
- Trial name
- NCT03320473
- Testing
- IC-8 IOL
- Where
- Philippines
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Cataract
Functional Vision With ACRYSOF® IQ IOLs Blue Light Filtration
The purpose of this study is to compare the reaction time (as measured by braking reaction time in seconds during simulated driving) under glare and no-glare conditions in subjects implanted with ACRYSOF® IQ intraocular lenses…
- Trial name
- NCT02219997
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses, ACRYSOF® IQ IOL
- Volunteers
- 90 people
- Sponsor
- Alcon Research
Dysphotopsia, Posterior Capsule Opacification
Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants
The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL)…
- Conditions
- Dysphotopsia, Posterior Capsule Opacification, Visual Acuity, Visual Function
- Trial name
- NCT07213167
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Daniel H. Chang, MD
Primary Open Angle Glaucoma
24h Continuous Intraocular Pressure (IOP) Monitoring vs Goldmann Applanation Tonometry
A study in which intraocular pressure (IOP) will be monitored over 24 hours using the SENSIMED Triggerfish® device and Goldmann applanation tonometry (GAT) in primary open angle glaucoma patients.
- Trial name
- NCT01217853
- Testing
- SENSIMED Triggerfish
- Where
- 2 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Sensimed AG
Cataract
Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).
Randomized contralateral clinical trial with single piece (Model SN60WF) vs. three piece (Model MA60AC) AcrySof Intraocular Lenses (IOLs) on development of Posterior Chamber Opacifiation (PCO).
- Trial name
- NCT00758745
- Testing
- Model SN60WF, Model MA60AC
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)
The purpose of this study was to evaluate and compare postoperative corneal aberrations and visual parameters in patients contralaterally implanted with an AcrySof IQ Toric intraocular lens (IOL) and AcrySof IQ Aspheric IOL with…
- Trial name
- NCT01045733
- Testing
- AcrySof IQ Toric IOL, AcrySof IQ Aspheric IOL, Limbal Relaxing Incision (LRI)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Pseudophakia
Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation
The purpose of this study is to compare the long-term visual acuity (VA) with an acrylic IOL to a silicone or polymethylmethacrylate (PMMA) IOL in cataract patients. This study will take place in Japan.
- Trial name
- NCT02450799
- Testing
- Acrylic IOL, Silicone IOL, PMMA IOL
- Volunteers
- 104 people
- Sponsor
- Alcon, a Novartis Company