Clinical trials: Intraocular Lenses
Cataract
Visual Outcome and Visual Quality After Bilateral Implantation of the AcrySof® IQ IOL Compared to MI60® and Tecnis® IOL
The objective of the study is to compare the visual outcomes of three aspheric monofocal intraocular lenses after cataract surgery - ACRYSOF® IQ, Tecnis® and Akreos® MI60.
- Trial name
- NCT00760058
- Testing
- AcrySof® IQ IOL, Tecnis® Aspheric intraocular lens, Akreos® MI60 intraocular lens
- Where
- United States
- Sponsor
- Alcon Research
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Cataracts
Clinical Investigation of Corneal Incision Size After Intraocular Lens (IOL) Implantation
The purpose of this study is to compare corneal incision size after IOL implantation with the use of one of four IOL delivery systems (three preloaded IOL delivery systems and one manually loaded IOL delivery system).
- Trial name
- NCT02826421
- Testing
- UltraSert Preloaded Delivery System, iTec Preloaded Delivery System, iSert Preloaded Delivery System
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Cataract, Glaucoma
Comparison of Phaco-Trabeculectomy and MSICS-Trab in Cataract and Glaucoma Patients
The goal of this interventional study is to compare the outcomes of two surgical techniques, Phaco-Trabeculectomy and Manual Small Incision Cataract Surgery (MSICS) with Trabeculectomy, in patients with coexisting cataract and…
- Trial name
- NCT06739343
- Testing
- PHACO-Trabeculectomy, MSICS-Trabeculectomy
- Where
- Nigeria
- Volunteers
- 122 people
- Sponsor
- Emeka John Dingwoke
Myopia
Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) Implantation
This study evaluates the safety and efficacy of a viscoelastic-free method for Implantable Collamer Lens(ICL) implantation to treat high myopia.
- Trial name
- NCT03059043
- Testing
- viscoelastic-free implantation system, standard viscoelastic-assisted Implantation system
- Where
- 5 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Cataract, Presbyopia
Objective and Subjective Outcomes of a Trifocal IOL in Eyes With Different AL
This prospective cohort study enrolled patients with implantation of a trifocal IOL. Only one eye of each patient was enrolled. Eyes were devided into three groups according the axial length (AL), including the short AL group…
- Conditions
- Cataract, Presbyopia, Lenses, Intraocular, Myopia
- Trial name
- NCT05431868
- Testing
- AT LISA tri 839MP (Carl Zeiss Meditec AG)
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Intraocular Lens Implantation
Clinical Validation Plan of Capsular Tension Ring
Through follow-up for 1 year or more, the safety and effectiveness of the Capsular Tension Ring produced by Eyebright Medical Technology (Beijing) Co., Ltd.
- Trial name
- CVPOCTR (NCT04880018)
- Testing
- Capsular Tension Ring
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eyebright Medical Technology (Beijing) Co., Ltd.
Cataract, Intraocular Pressure
Effect of Fixed Brinzolamide-brimonidine Combination on Intraocular Pressure After Phacoemulsification
This study aims to evaluate the effect of fixed brinzolamide-brimonidine combination on intaocular pressure after uncomplicated phacoemulsification surgery.
- Trial name
- NCT03494257
- Testing
- Brinzolamide-Brimonidine fixed combination
- Where
- Greece
- Volunteers
- 62 people
- Sponsor
- University Hospital of Patras
Age Related Cataracts
Evaluation of Physiological Responses at the Anterior Surface of Two (Hydrophobic Acrylic) Intraocular Lens Models
On the day of surgery, the the eye with astigmatism of at least 0.75dpt receives a Vivinex XY1A , HOYA Surgical Optics GmbH and the second eye to be operated receives an XY1, HOYA Surgical Optics GmbH.
- Trial name
- NCT04230629
- Testing
- Vivinex XY1, Vivinex XY1A
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cataracts
Acrysof Toric SN60T3corneal Astigmatism Between 0.75 and 1.00 D.
The purpose of this study is to evaluate the visual outcomes and patient satisfaction after implantation of a toric IOL in patients with predicted residual corneal astigmatism between 0.75 and 1.00 D.
- Trial name
- TORILIOL (NCT00542581)
- Testing
- The Acrysof toric SN60T3 IOL
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Medical University of South Carolina
Tilt and Decentration
Comparison of Methods for Assessing Intraocular Lens Position
Prospective, multi-center, non-interventional, open label, clinical study.
- Trial name
- NCT07218419
- Testing
- IOL Decentration Assessment
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract
Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)
The purpose of this study is to evaluate the safety and effectiveness of a new investigational modified light transmission monofocal intraocular lens compared to a conventional intraocular lens (IOL).
- Trial name
- NCT00747227
- Testing
- modified light transmission intraocular lens, monofocal acrylic intraocular lens
- Where
- 11 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract
Cataract Surgery With Intracameral Triamcinolone in Infants
The aim of the present study is to investigate the outcomes of congenital cataract surgery when injecting intraoperative intracameral triamcinolone versus the postoperative use of oral prednisolone.
- Trial name
- NCT01800708
- Testing
- Triamcinolone acetonide, Prednisolone syrup
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Fundação Altino Ventura
Fuch's Endothelial Dystrophy, Cataracts
Study of the Effect of Aspheric Lenses in Patients With Fuch's Dystrophy
The proposed study will recruit patients with mild to moderate Fuch's dystrophy who need cataract surgery alone. They will be randomly assigned to receive either spheric or aspheric lenses.
- Trial name
- NCT02109276
- Testing
- Spheric Sensar(R) 3-piece IOL, Aspheric Tecnis(R) 3-piece IOL
- Where
- Canada
- Sponsor
- Queen's University
Refractive Errors
Trifocal Diffractive Intraocular Lens After Cataract Extraction With Phacoemulsification
Multifocal IOLs that maintain distance focus and improve near vision have been developed to reduce spectacle dependence.Multifocal IOLs improve patient performance of near-vision tasks, such as reading crafts, hobbies, and social…
- Trial name
- NCT04465279
- Testing
- Trifocal diffractive intraocular lens
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Astigmatism
A Comparison of the Accuracy of Toric Intraocular Lens Formulas
To compare the accuracy of the Abulafia-Koch, the Barrett, the Barrett Post ,the EVO , the new Holladay with total surgical-induced astigmatism, the Kane and and the Næser-Savini toric intraocular lens (IOL) power formulas using…
- Trial name
- NCT04776603
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Wenzhou Medical University
Capsulorhexis
Evaluation of Centration of Intraocular Lens With Two Settings for Capsulorhexis With Femtosecond Laser
The study compares anatomic outcomes of Intra Ocular Lens(IOL) placement with two methods of centration of the capsulorhexis- scanned capsule centration and pupil centration.
- Trial name
- NCT02315456
- Testing
- capsulorhexis
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cataract
Predicting Lens Tilt Using Optical Coherence Tomography and Partial Least Squares Regression Modelling
Misalignment of IOLs can cause severe loss of visual quality. Different types of misalignment are known. Tilt is one type of misalignment that is thought to play a negative role for the optical performance in eyes with IOL…
- Trial name
- Tilt (NCT05915429)
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Glaucoma
High Frequency Deep Sclerotomy (HFDS) ab Interno a Combination Surgical Intervention Using Cataract Surgery to Lower IOP
Objective: To compare intraocular pressure lowering effect of combined sclerotomy ab interno with phacoemulsification and phacoemulsification alone, in primary or secondary open angle glaucoma patients.
- Conditions
- Cataract, Glaucoma, POAG
- Trial name
- HFDS_abinterno (NCT02312362)
- Testing
- Combined sclerotomy ab interno and phaco, Phacoemulsification with IOL implantation
- Where
- 5 sites in Egypt, Germany and 2 more
- Volunteers
- 108 people
- Sponsor
- Oertli Instrumente AG
Aniridia, Eye Abnormality
Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and Lens
This study will investigate congenital or developmental eye abnormalities that affect the iris, cornea and lens, and are usually accompanied by elevated pressure within the eye.
- Conditions
- Aniridia, Eye Abnormality, Ocular Hypertension, Open Angle Glaucoma
- Trial name
- NCT00001161
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Eye Institute (NEI)