Clinical trials: Intraocular Pressure
Primary Open Angle Glaucoma (POAG)
One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
The purpose of this study is to evaluate the safety and efficacy of the intraocular pressure (IOP) lowering effect of one, two, or three iStent devices in eyes of subjects previously on two anti-glaucoma medications.
- Trial name
- NCT01517477
- Testing
- iStent
- Where
- Armenia
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Glaukos Corporation
Glaucoma
Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and Corvis ST Tonometer
The study is investigating Intra ocular pressure (IOP) by Goldmann Applanation Tonometry, Dynamic Contour Tonometry, and the Corvis ST tonometer.
- Trial name
- NCT02624427
- Testing
- Measurement of intraocular pressure (IOP)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Intraocular Pressure and PROSE Lens
Tonometry Precision and Accuracy During PROSE Scleral Lens Wear: A Pilot Study
The goal of this research is to determine the reproducibility of measurements of intraocular pressure (IOP) when a scleral lens is on the eye.
- Trial name
- NCT04308941
- Testing
- Intraocular pressure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Sight
Intra Ocular Hypertension
The Effect of Two Different Artificial Respiration Methods on the Intraocular Pressure During Surgery Under General Anesthesia
The purpose of this study is to examine whether the intraocular pressure of operated people under general anesthesia is affected by the artificial respiration method.
- Trial name
- NCT01567761
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Intraocular Pressure
The Response of Intraocular Pressure to Systemic Hypercapnia and Hyperoxia
The purpose of this study is to determine how intraocular pressure responds to changes in the levels of carbon dioxide or oxygen that a healthy individual inspires.
- Trial name
- NCT01325285
- Testing
- RespirAct
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Volunteers
SENSIMED Triggerfish Sensor Sizes
This is a study investigating the effect of various SENSIMED Triggerfish sensor lens sizes on the recorded IOP related patterns in 10 healthy volunteers.
- Trial name
- NCT01972997
- Testing
- SENSIMED Triggerfish
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Primary Open Angle Glaucoma, Ocular Hypertension
Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Tensor Imaging
Glaucoma is among the leading causes for blindness in the western world. Elevated intraocular pressure (IOP) has been identified as the most important risk factor.
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension, Normal Tension Glaucoma
- Trial name
- NCT01864317
- Testing
- 7-Tesla MRI, Optical Coherence Tomography, Heidelberg Retina Tomography
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Primary Open Angle Glaucoma (POAG)
Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects
The purpose of this study is to evaluate the safety and efficacy of the iStent medical device that is implanted into the eye and designed to reduce eye pressure in patients with your condition.
- Trial name
- NCT01252849
- Testing
- iStent
- Where
- Armenia
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Glaukos Corporation
Intraocular Pressure
External Influences Upon Ocular Homeostasis
Our experiments are designed to test the overall hypothesis that position-dependent or water-dependent intra-ocular pressure (IOP) spikes occur in humans, and that these challenge ocular homeostasis.
- Trial name
- NCT00338065
- Testing
- Postural change, Water drinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Intraocular Pressure
Set up for in-Vivo Measurement of Dynamic Intraocular Pressure (IOP)
In this modern era, surgeons prefer to perform emulsification through small micro incisions. To accomplish this safely, surgeons raise irrigation bottle heights or use forced infusion systems.We believe that this sustained rise…
- Trial name
- NCT00856141
- Testing
- phacoemulsifcation
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Robot-Assisted Laparoscopic Radical Prostatectomy
The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Intraocular pressure is significantly increase during robot-assisted laparoscopic radical prostatectomy which is performed in a steep trendelenburg position at prolonged times of pneumoperitoneum.
- Trial name
- NCT02109133
- Testing
- deep neuromuscular blockade, moderate neuromuscular blockade, Rocuronium
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Glaucoma
Non-Contact Air Tonometry (Topcon CT-1®) Versus Goldmann
In this prospective device comparison study with 58 healthy eyes, the Topcon CT-1® showed statistically significant elevated intraocular pressure measurements compared to the gold standard Goldmann application tonometry.
- Trial name
- NCT03684174
- Testing
- Intraocular pressure measurement
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Zurich
POAG, Primary Open Angle Glaucoma
A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of Glaucoma
The purpose of the study is to provide evidence that the efficacy of Xalatan will be superior to Apo-latanoprost and Co-latanoprost in the reduction of intraocular pressure in patients with primary open angle glaucoma.
- Conditions
- POAG, Primary Open Angle Glaucoma, Ocular Hypertension
- Trial name
- NCT02792803
- Testing
- Xalatan, Apo-Latanoprost, Co-Latanoprost
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. David Yan
Open Angle Glaucoma
Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle Glaucoma
The purpose of this study is to evaluate the effectiveness of a new laser (called Micropulse Laser Trabeculoplasty or MLT) in the treatment of glaucoma compared to the conventional laser presently used which is called selective…
- Trial name
- NCT01956942
- Testing
- Micropulse Laser Trabeculoplasty, Selective Laser Trabeculoplasty
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- David Belyea
Intraocular Pressure
Effect of Raised End-Tidal pCo2 on Choroidal Volume
This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.
- Trial name
- NCT06275308
- Testing
- Ventilation manipulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Ocular Hypertension, Glaucoma
Foot Reflexology in Ocular Hypertensive and Glaucoma Patients
To determine the effect of foot reflexology in primary open angle glaucoma (POAG) patients and the effect of a shoe insert to perform continuous foot reflexology in ocular hypertensive (OHTN) patients.
- Trial name
- NCT04695314
- Testing
- Massage, Experimental insert
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Temple University
Intraocular Pressure
Eyenovia MiDD Usability Study
This study is to evaluate the usability and patient tolerability for microtherapeutic dosing of commercially available ocular medication via the Eyenovia microdose delivery system (MiDD)
- Trial name
- NCT03480906
- Testing
- Latanoprost
- Where
- Panama
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Intraocular Pressure
Acute Effects of HIIT and SSMIT on Intraocular Pressure Among Sedentary Individuals
Purpose to study the acute effects of both forms of aerobic exercise (HIIT and SSMIT) on intraocular pressure among healthy sedentary individuals
- Trial name
- NCT04133857
- Testing
- aerobic exercise
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Glaucoma, Open-Angle, Healthy
Sensing Contact Lens-based Device for 24-hour Monitoring of Intraocular Pressure
Glaucoma is characterized by irreversible vision loss through the progressive death of optic nerve fibers unless timely diagnosis and adequate treatment are provided.
- Trial name
- NCT03689088
- Testing
- Goldfish, Tonometry
- Where
- Poland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Healthy Subjects
Water Drinking Test During Intraocular Pressure Fluctuation (IOP) Monitoring
The purpose of this study is to investigate the investigational device capacity to detect an intraocular pressure increase (IOP)induced by water intake.
- Trial name
- NCT01362868
- Testing
- SENSIMED Triggerfish®
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sensimed AG