Clinical trials: Intraocular Pressure
Choroidal Neovascularization
Intraocular Pressure Immediately Following Intravitreous Injection of Ranibizumab
This study will quantify the intraocular pressure elevation in the immediate time period following intravitreous injection. With more widespread use of intravitreous injections in patients that may require several injections per…
- Trial name
- NCT00417703
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Healthy
Measurement of Pulse Wave Velocity
Optically-based data will be compared to tonometry to determine correlation of pulse wave velocity measurement.
- Trial name
- NCT02444650
- Testing
- Pulse wave velocity measurement Photoplethysmogram, tonometer
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nonin Medical, Inc
Glaucoma, Intraocular Pressure
Intraocular Pressure Fluctuation in Patients With Glaucoma and in Healthy Patients During Standard Yoga Positions
The purpose of the study is to investigate the IOP difference between normal and glaucomatous eyes using standard ophthalmic tonometry devices while subjects are performing different standard yoga asanas.
- Trial name
- NCT01915680
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Robert Ritch, MD, LLC.
Intraocular Pressure
Steep Trendelenburg Positioning on Intra-Ocular Pressure During Surgery for Endometrial Robotics Versus Laparotomy
The purpose of this study is to assess changes of intra-ocular pressure (IOP) and examine preoperative facts affecting IOP in endometrial cancer patients undergoing robotic hysterectomy compared to laparotomy.
- Trial name
- NCT00852774
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Glaucoma
Intraocular Pressure (IOP) Lowering Efficacy of Transdermal Brimonidine Therapy
The purpose of this study is to evaluate the safety and effectiveness in lowering intraocular pressure (IOP) utilizing an experimental lotion containing 0.1% Brimonidine that is applied to the outside of one eyelid.
- Trial name
- NCT01345448
- Testing
- Brimonidine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Nanduri, Padma, M.D., FACS
Nail Growth Cessation, Intraocular Pressure
Cutaneous Prostaglandin Application: Nail Growth, Nail Brittleness, and Eye Pressure
Topical prostaglandin agents are used to help reduce eye pressure in glaucoma patients. Bimatoprost (Lumigan 0.01%) is such an agent (Allergan, Inc.).
- Trial name
- NCT02448043
- Testing
- Bimatoprost 0.01%
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Normal Tension Glaucoma
IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic
The primary purpose of this study is to determine whether topical ophthalmic anesthetics lower the intraocular pressure in the eye.
- Trial name
- NCT01254149
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Normal-Tension Glaucoma
Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma
Purpose: To study the feasibility of a larger study by determining the tolerability of measuring blood pressure (BP) and intraocular pressure (IOP) over 24 hours in an ambulatory fashion with automatic devices.
- Trial name
- NCT01912599
- Testing
- Sensimed Triggerfish, Blood Pressure
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
Regulation of Optic Nerve Head Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Autoregulation is the ability of a vascular bed to maintain blood flow despite changes in perfusion pressure. The existence of an effective autoregulation in the optic nerve head (ONH) circulation has been shown in animals and…
- Trial name
- NCT00915226
- Testing
- Suction cup application, Squatting
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Intraocular Pressure
Comparative Study of the NIDEK TONOREF III and the Haag-Streit Goldmann Manual Tonometer and Comparison of Pachymetry Values for NIDEK TONOREF III With the NIDEK CEM-530
The primary objective of this clinical study is to prove that tonometry values for NIDEK TONOREF III are comparable to the predicate device and to prove that the pachymeter function of NIDEK TONOREF III is equivalent to the…
- Trial name
- NCT03441477
- Testing
- Nidek Tonoref III, Haag-Streit Goldmann Manual Tonometer, NIDEK CEM-530
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Intraocular Pressure
Effects of Intubation on Intra-ocular Pressure and Optic Nerve Sheath Diameter
Brief Summary: In this study, the investigators aimed to compare the effects of different types of endotracheal instruments (Machintosh laryngoscope, McGrath videoingoscope and C-Mac videoryngoscope) on intraocular pressure…
- Trial name
- [Intubation] (NCT05763056)
- Testing
- McGrath videolaryngoscopy, C-MAC videolaryngoscopy, Direct laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anesthesia
Clonidine Added Lidocaine in Intraocular Pressure and Hemodynamics Ocular in Sub-Tenon's and Peribulbar Anesthesia
Regional anesthesia in orbit can reduce ocular blood flow, increase in intraocular pressure (IOP) or the pharmacological action of local anesthetics.
- Trial name
- NCT02733757
- Testing
- Clonidine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Pain
Assessment of Comfort Level Following an Intravitreal Injection by 30 or 32 Gauge Needles
The purpose of this study is to determine if a smaller needle size reduces discomfort suffered by patients both during and following intravitreal injections.
- Trial name
- NCT02142114
- Testing
- Eye injection by 30 or 32 gauge needle
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Retina Health Center
Physiology
Effects of Intravenous Clonidine on Ocular Blood Flow and Intraocular Pressure
Background Clonidine, a derivate of Imidazol, is an antihypertensive drug. It acts by stimulating adrenergic receptors on nerves in the brain and Imidazol-receptors.
- Trial name
- NCT00279253
- Testing
- clonidine (drug) intravenously
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Glaucoma, Intraocular Pressure
Effect of Topical Dexmedetomidine on Intraocular Pressure
Evaluate the short-term safety and efficacy of dexmedetomidine (0.0055%) drops on intraocular pressure (IOP) in healthy eyes.
- Trial name
- NCT03690622
- Testing
- Dexmedetomidine, Balanced salt solution
- Where
- Lebanon
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Beirut Eye Specialist Hospital
Open Angle Glaucoma, Ocular Hypertension
Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure
The purpose of this study is to determine whether 24-hour fluctuation of intraocular pressure (IOP) is associated with central corneal thickness (CCT) in subjects with ocular hypertension or open angle glaucoma and in age-matched…
- Trial name
- CCT-IOP (NCT00941525)
- Testing
- Latanoprost
- Where
- Greece
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Cardiorespiratory Fitness, Eye Disorders
Ralation Between Cardiorespiratory Fitness and Mean Corrected Intraocular Pressure
Objective: To investigate the association between cardiorespiratory fitness and mean corrected intraocular pressure (IOP) in a normotensive health check-up population, and to evaluate potential differences across age and sex…
- Trial name
- NCT07676747
- Testing
- Mean corrected intraocular pressure (IOP) of both eyes
- Where
- China
- Volunteers
- 2,921 people, healthy volunteers welcome
- Sponsor
- Sichuan Academy of Medical Sciences
Intraocular Pressure
Icare Versus Haag-Streit Applanation Tonometer
The clinical performance of Icare ONE Tonometer TA02 was compared to a Goldmann type applanation tonometer (Haag-Streit). Data was collected according to ANSI Z80.10-2003 (ISO 8612.2) standard.
- Trial name
- NCT01159340
- Where
- Finland
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Intraocular Pressure, Glaucoma
Comparison of Intraocular Pressure Measurements Between Reichert Tono-Vera Tonometer and Goldmann Tonometry
Determine if the Tono-Vera Tonometer accurately measures intraocular pressure (IOP). The hypothesis of this test is to confirm the Tono-Vera Tonometer is equivalent to the Goldmann Applanation Tonometer (within +/- 5.0 mmHg).
- Trial name
- NCT04360369
- Testing
- IOP with Goldmann Applanation Tonometer, IOP with comparator ORA G3 and ic100 tonometers, IOP with Tono-Vera Tonometer
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Reichert, Inc.
Inflammation
Ocular Tolerance and Intraocular Pressure (IOP) Effects of Zylet Versus Tobradex
Phase IV, randomized, double-masked, parallel-group clinical trial comparing the ocular tolerability and steroid-induced intraocular pressure (IOP) effects of Zylet wth that of TobraDex in healthy volunteers, when either product…
- Trial name
- NCT00532961
- Testing
- Loteprednol etabonate 0.5% and tobramycin 0.3%, Dexamethasone 0.1% and tobramycin 0.3%
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated