Clinical trials: Intraoperative Analgesia
Osteoarthritis
The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty
The purpose of this study is to use a new combination of anesthesia techniques in an attempt to minimize early pain after surgery and improve the patient's ability to participate more fully with physical therapy.
- Trial name
- NCT00620828
- Testing
- Ropivicaine 0.5%
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
Post-operative Pain
Intraoperative TAP Block After Repeat Cesarean
The aim of this study is to perform a randomized trial to investigate if intraoperative surgeon administered TAP block reduces pain and use of oral and parenteral pain medications after repeat cesarean delivery.
- Trial name
- NCT05393908
- Testing
- TAP Block Group
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Post Operative Analgesia, Non-inferiority Trial
Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: Surgeon vs Anesthesia - Ultrasound Guidance
The transversus abdominis plane (TAP) block is a regional anesthesia technique where local anesthetic is injected into the neurovascular plane between the transversus abdominis and internal oblique muscles.
- Trial name
- NCT03577912
- Testing
- TAP block administered by Surgery, TAP block administered by Anesthesia
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Perioperative Pain Management
The Efficacy of Music on Perioperative Pain Management
The goal of this clinical trial is to learn if intraoperative music stimulation works to alleviate perioperative pain in surgical patients undergoing general anesthesia.
- Trial name
- NCT06467747
- Testing
- Music, Mute
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taichung Tzu Chi Hospital
Operative Incision
Effect of Intraoperative Ankle Nerve Blocks on Postoperative Discharge in Patients Undergoing Orthopaedic Foot Surgery
Postoperative pain is an important clinical issue which negatively affects patient's satisfaction, delays discharge and repeated admission after discharge in orthopedic surgery.
- Trial name
- NCT03550677
- Testing
- general anesthesia, ankle block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
No Disease or Condition is Being Studied
ANI-Guided Fentanyl Infusion During Living Donor Liver Resections
Thу goal of this study was to learn whether intraoperative analgesia nociception monitoring (ANI) could be beneficial during intraoperative monitoring for patients undergoing living donor liver resections.
- Trial name
- NCT06619977
- Testing
- Analgesia nociception monitoring (ANI)
- Where
- Ukraine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bogomolets National Medical University
Analgesia, Nociceptive Pain
Effect of ANI on Intraoperative Opioid Consumption
The aim of the study is to compare the analgesic nociception index (ANI), which is used to determine the dose of analgesic agent needed in the intraoperative period, with the conventional method in patients with erector spinae…
- Conditions
- Analgesia, Nociceptive Pain, Nerve Block, Pain
- Trial name
- NCT05106452
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Erector Spinae Plane Block
Effectiveness of Bilateral Ultrasound-Guided Erector Spinae Plane Block
The proposed mechanism of action of the ESPB is via blockade of the dorsal and ventral rami of the spinal nerves and sympathetic nerve fibers.
- Trial name
- NCT04110210
- Testing
- Bilateral Ultrasound-Guided Erector Spinae Plane Block, Morphine Consumption
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Comparison of Intraoperative Intravenous Lidocaine Infusion and Transversus Abdominis Plane (TAP) Block for Post-operative Analgesia Following Laproscopic Cholecystectomy
This study is aimed to determine the post operative pain after laparoscopic cholecystectomy by dividing patients into three different group.
- Trial name
- NCT05231941
- Testing
- Lidocaine IV, Ropivacaine
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Osteoarthritis, Degenerative Joint Disease
Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement
The purpose of this study is to clarify the efficacy of a multidrug versus single drug periarticular injection when only standard operative and postoperative pain management protocols used and the control group is exposed to what…
- Trial name
- NCT03119038
- Testing
- Bupivicaine + epinephrine, Bupivacaine, Ropivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Postoperative Pain Control, Breast Reduction
Surgeon-Guided Serratus Block in Breast Reduction Surgery
Surgeon guided serratus block, which can be performed by the surgeon in participants undergoing breast reduction surgery, may reduce the sensation of pain from the surgical field in the postoperative period.
- Trial name
- NCT06905574
- Testing
- surgeon guided serratus block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- alperen can kokten
Post Operative Pain, Acute
Effect of Preoperative Oral Pregabalin Versus Intraoperative Fentanyl on Postoperative Analgesia
Pregabalin is a structural analogue of gamma amino butyric acid (GABA). It binds to presynaptic alpha-2-delta subunit of voltage gated calcium channels in the brain and the spinal cord.
- Trial name
- NCT05150795
- Testing
- Pregabalin 150mg, Fentanyl 100 micrograms ampoule
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia
Magnesium for Shivering in Epidural Lidocaine Deliveries
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia…
- Trial name
- Mag-SHIELD (NCT03439358)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Liver Failure, Liver Transplant; Complications
Intravenous Ketamine Infusion on Postoperative Analgesia of Living Liver Donors
Because of the insufficiency of cadaveric organs and increasing need for organs, the interest in living donor liver transplantation have been greatly increased.
- Conditions
- Liver Failure, Liver Transplant; Complications, Post Operative Pain
- Trial name
- NCT05441150
- Testing
- Low dose ketamine infusion, 0.9% NaCl infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pain
Pupillometry - Future of Objective Pain Reaction Measurement While Unconscious
This study aims to assess the usefulness of pupillometry as a nociceptive indicator during elective orotracheal intubation in patients given intravenous lignocaine pre-intubation as compared to a placebo pre-intubation.
- Trial name
- NCT04000126
- Testing
- Pupil reflex dilation measurement (PRD), PPI (Pupillary Pain Index), lidocaine
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury
Postoperative Pain
Intraoperative Methadone for Postoperative Pain Control After Thoracic Surgery
Pain following surgery continues to be an important adverse outcome that may impact postoperative recovery. Opioids like fentanyl and hydromorphone are the primary medications used to provide analgesia, but paradoxically, may…
- Trial name
- NCT04525898
- Testing
- Methadone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Analgesia, Analgesia, Epidural
Postoperative Analgesia in Major Gynecological Cancer Surgeries
The aim of this study is to compare the effectiveness of epidural block or erector spinae plane block applied for postoperative analgesia in gynecological cancer surgeries.
- Conditions
- Analgesia, Analgesia, Epidural, ERAS
- Trial name
- NCT06424938
- Testing
- Patients who underwent epidural block, Patients who underwent erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Pain Monitoring, Pain Assessment
Intraoperative Analgesia Based on ANI
Osteoarthritis of the knee joint is common and total knee arthroplasty (TKA) is performed in patients with advanced joint degeneration, no response to conservative treatments, severe pain and joint instability.
- Conditions
- Pain Monitoring, Pain Assessment, Opioid Consumption
- Trial name
- NCT06236035
- Testing
- Analgesia nociception index
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University