Clinical trials: Intraoperative Hemodynamics
Intraoperative Hypotension
The Predict H Trial
The aim of the study is to determine whether a goal-directed algorithm based on the prevention of arterial hypotension using the Hypotension Prediction Index reduces the duration and severity of intraoperative hypotension when…
- Trial name
- NCT04301102
- Testing
- Hemosphere platform® together with the FloTrac Acumen IQ® sensor, Hemosphere platform® together with the FloTrac® sensor
- Where
- 5 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Juan Victor Lorente
Laparoscopic Renal Surgery, Laparoscopy
Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory Mechanics
The primary objective of the current study is to compare intraoperative respiratory mechanics in patients receiving laparoscopic renal surgery under deep neuromuscular blockade (dNMB) and under moderate neuromuscular blockade…
- Conditions
- Laparoscopic Renal Surgery, Laparoscopy, Muscle Relaxation
- Trial name
- NCT02185339
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Seoul St. Mary's Hospital
Sedoanalgesia
Effects of Preoperative Anxiety and Pain Sensitivity in Cases of Endoscopic Ultrasonography Received Sedoanalgesia
The objective of this study was to detect whether preoperative anxiety and pain sensitivity had effects on the consumption of anesthetics, time to achieve desired level of sedation, patient and endoscopist satisfaction, and…
- Trial name
- NCT03114735
- Volunteers
- 80 people
- Sponsor
- Istanbul Medeniyet University
Ultrasound, Machine Learning
Intelligent Classification of Intraoperative Hemodynamic Phenotypes Based on CADFlow Doppler Monitoring
The goal of this observational study is to learn about intraoperative hemodynamic phenotypes in adult patients undergoing elective surgery under general anesthesia, using a new wearable ultrasound patch (CADFlow) that…
- Conditions
- Ultrasound, Machine Learning, Intraoperative Hypotension, Hemodynamic Monitoring
- Trial name
- NCT06957587
- Where
- 2 sites in China
- Volunteers
- 440 people
- Sponsor
- Shanghai 6th People's Hospital
Intraoperative Hypotension
Effects of Sufentanil on the Intraoperative Hemodynamics
This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.
- Trial name
- NCT06091904
- Testing
- Sufentanil, Remifentanil
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Postoperative Troponin Elevation, Intraoperative Perfusion
Impact of Intraoperative Perfusion Variability on Postoperative Troponin Elevation in Geriatric Patients Undergoing Major Oncologic Surgery
This prospective observational study aims to evaluate the association between intraoperative perfusion variability and postoperative troponin elevation in geriatric patients undergoing major oncologic surgery.
- Trial name
- NCT07786753
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Fragility, Intraoperative Hypotension
The Effect of Frailty to Perioperative Complications in the Elderly
With the progression of population aging, the number of elderly patients undergoing surgery is increasing as well. However, as the condition of health differs greatly between individual elderly patients even of the same age, it…
- Conditions
- Fragility, Intraoperative Hypotension, Perioperative Complication
- Trial name
- NCT04120012
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Peking Union Medical College Hospital
Intraoperative Hemodynamics, Liposuction
Effect of Adrenaline Concentration on Intraoperative Hemodynamics of Liposuction Patients
Liposuction is a procedure that has emerged over the last 30 years as a method to remove subcutaneous fat for cosmetic purposes.
- Trial name
- NCT05822765
- Testing
- Epinephrine concentration of 1:1000000, Epinephrine concentration of 1:500000
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Surgery, Hemodynamic Instability
Cell Salvage and Retrograde Autologous Priming
In recent years Patient Blood Management (PBM) has developed into a multifactorial and interdisciplinary concept that focuses on individualized and optimized hemotherapy.
- Trial name
- NCT04792814
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Schleswig-Holstein
Major Abdominal Surgery, Duodenohemipancreatectomy
Intraoperative Haemodynamic Optimization Comparing Flow and Pressure Parameters
The purpose of the study is to confirm the hypothesis that flow treatment algorithm based on cardiac index trending by transesophageal Dopplerometry would result in reduced complications and reduced length of hospital stay in…
- Conditions
- Major Abdominal Surgery, Duodenohemipancreatectomy, Rectal Resection, Extensive Bowel Surgery
- Trial name
- Flow-press (NCT02104687)
- Testing
- Flow group, Press group
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- University Hospital Ostrava
Pheochromocytoma, Non-Secretory Adrenal Adenoma
Intraoperative Hemodynamic Instability During Unilateral Adrenalectomy for Pheochromocytoma
Pheochromocytomas are tumors of the adrenal gland that develop from cells producing adrenaline and noradrenaline. Consequently, intraoperative blood pressure variations (hypertensive and hypotensive episodes) are characteristic…
- Trial name
- HEMODADRE (NCT06062082)
- Testing
- adrenalectomy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Whipple Procedure, Intraoperative Hemodynamic Management
MAP- Versus Cardiac Index-Guided Hemodynamic Management in Whipple Surgery
This prospective randomized study aims to compare the effects of two intraoperative hemodynamic management strategies on early postoperative renal function in patients undergoing pancreaticoduodenectomy.
- Trial name
- NCT07603336
- Testing
- Mean Arterial Pressure-Guided Hemodynamic Management, Cardiac Index-Guided Hemodynamic Management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Anesthesia and Analgesia, Laparoscopic Surgical Procedure
Record and Analyze the Data of Patient Undergoing Anesthesia for Laparoscopic Cholecystectomy From Patient Monitoring Instruments
To record the digital data from monitoring instruments (standard patient monitor) containing cardiovascular system information, and from depth-of-anesthesia monitoring modules (Bispectral index, Entropy module, Surgical…
- Conditions
- Anesthesia and Analgesia, Laparoscopic Surgical Procedure, Monitoring, Physiologic, Hemodynamic Monitoring
- Trial name
- NCT03691103
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Intraoperative Hypotension
Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia
This study investigates if the Hypotension Prediction Index (HPI) combined with the Assisted Fluid Management (AFM) software can improve perioperative hemodynamic management in adult patients undergoing general anesthesia.
- Trial name
- NCT07301307
- Testing
- Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software, Conventional Intraoperative Hemodynamic management
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Intraoperative Hypotension, Hemodynamic Instability
Hypotension Prediction With HPI Algorithm During Major Gynecologic Oncologic Surgery
Intraoperative hypotension (IOH) is a rather common event during general surgery, with variable incidence that ranges between 5 and 99% based on the definition used.
- Conditions
- Intraoperative Hypotension, Hemodynamic Instability, Gynecologic Cancer
- Trial name
- HPI-GOS (NCT04547491)
- Testing
- HPI - hypotension prediction index, GDT
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pheochromocytoma, Paraganglioma
Correlation Between Preoperative Images of PPGL and Intraoperative Hemodynamics
This is a retrospective observational cohort study involving patients with suspected PPGLs who underwent 131I-MIBG scanning and surgical treatment between January 2020 and April 2023.
- Trial name
- NCT06669481
- Testing
- Semiquantitative 131I-MIBG Scintigraphy Assessment
- Where
- China
- Volunteers
- 159 people
- Sponsor
- Peking Union Medical College Hospital
Mechanical Ventilation
The Effect of Intraoperative Ventilation Mode on Hemodynamics and Lung Dynamics
In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery…
- Trial name
- NCT05776589
- Testing
- The mechanical ventilation mode
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Izmir Ataturk Training and Research Hospital
Hyperthermia, Colorectal Neoplasms
Impact of an Optimised Monitored Anesthesia on the Patients' Recovery After Cytoreduction Surgery Plus HIPEC
The objective of our PILOT study is to evaluate the impact of a controlled (monitored) randomized anesthesia during cytoreductive surgery with HIPEC to oxaliplatin in order to treat adenocarcinomas of colorectal origin.
- Conditions
- Hyperthermia, Colorectal Neoplasms, Oxaliplatin
- Trial name
- CHIPNOL (NCT04104334)
- Testing
- Remifentanil infusion, desflurane titration and fluid infusion will be guided by NOL index, BIS index and Flotrac EV1000 system respectively, Remifentanil infusion and desflurane titration will be guided by anesthesia usual practices
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Shoulder Arthropathy Associated With Other Conditions
Effect of Liberal Versus Restrictive Intraoperative Fluid Therapy on Postoperative Pulmonary Complications and Hemodynamics in Patients Undergoing Shoulder Arthroscopic Surgery.
The primary aim of our study is to leverage lung ultrasound to assess and identify postoperative pulmonary complications following shoulder arthroscopic surgery and the implications of the used irrigation fluid.the investigators…
- Trial name
- NCT06104020
- Testing
- Intraoperative fluid management stratigies.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hemodynamic (MAP) Stability
Unilateral Spinal vs General Anaesthesia in Low EF Patients: A Hemodynamic Comparison
A difference exists in intraoperative hemodynamic stability and vasopressor requirement between the two techniques
- Trial name
- NCT07752303
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Sargodha Medical College