Clinical trials: Intraoperative Injury
Thyroid Diseases, Surgical Injury
Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid Surgery
For successful intraoperative neuromonitoring (IONM), adequate reversal of neuromuscular blocking agent is a prerequisite in thyroid surgery with .
- Conditions
- Thyroid Diseases, Surgical Injury, Nerve Monitoring
- Trial name
- NCT04873531
- Testing
- Neostigmine, Normal saline
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
Penile Implant Intraoperative Measurements Planning Chart
This is a chart of penile size measurements where penile length and width are recorded intra-operatively prior to penile prosthesis implantation to guide the surgeon to the correct and adequate post-operative penile size
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction With Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease
- Trial name
- PIIMP (NCT05531877)
- Testing
- Penile Prosthesis Implantation
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Orbital Fractures
Orbital Fractures Measurement: Intraoperative Versus Computed Tomography (CT) Scan
Purpose to compare the orbital fracture size measured by orbital CT scan and compare it to the actual orbital fracture size intraoperatively in patients who needed surgical intervention to correct the fracture.
- Trial name
- NCT01464541
- Testing
- operative fracture size vs CT fracture size, orbital fracture intraoperative measurement
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Abdominal Hysterectomy for Benign Disease
Electrosurgical Bipolar Plasmakinetic Vessel Sealing During Abdominal Hysterectomy: A Randomized Controlled Trial
Objective: To compare the safety and efficacy of the use of bipolar plasmakinetic vessel sealing (Gyrus Pk) usage versus standard technique when performing total abdominal hysterectomy for benign disease.
- Trial name
- PKAHRCT (NCT00654849)
- Testing
- Plasmakinetic bipolar energy forceps, Abdominal Hysterectomy with traditional suture technique
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Hospital de Concentracion Norte de Petroleos
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Abdominal Injuries
Feasibility and Usability of Intraoperative Fluorescent Angiography With Indocyanine Green in Penetrating Abdominal Trauma
The surgical management of penetrating bowel and intestinal injuries, inflicted via a gunshot or knife stabbing, has long been a topic of debate [1-3].
- Trial name
- NCT04534816
- Testing
- Indocyanine Green
- Where
- South Africa
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Subdural Hematoma
Template-Guided Burr-Hole Drainage With Middle Meningeal Artery Coagulation for Chronic Subdural Hematoma
Chronic subdural hematoma is a collection of blood and fluid on the surface of the brain that is common in older adults. Burr-hole drainage is a standard surgical treatment, but the hematoma may come back in some patients and…
- Trial name
- 3D-MMA-cSDH Tr (NCT07720687)
- Testing
- Standard Burr-Hole Drainage Group, 3D-Printed Template-Guided Burr-Hole Drainage With Attempted MMA Coagulation Group
- Where
- China
- Volunteers
- 440 people
- Sponsor
- The Second Hospital of Anhui Medical University
Hypotension, Brain Injuries
Correlation Between Circulating Biomarkers of Organs Damage and Intraoperative Hypotension Management
Intraoperative hypotension (defined as mean arterial pressure below 65 mmHg) is associated with increased organs dysfunction and mortality.
- Conditions
- Hypotension, Brain Injuries, Renal Failure, Endothelial Dysfunction
- Trial name
- NCT03527758
- Testing
- Flo TracIQ with HPI software
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Catania
Benign Multinodular Goiter, Thyroidectomy
Intraoperative Methylene Blue Spray for the Identification and Preservation of Vital Structures in Thyroidectomy
This randomized controlled trial aims to evaluate the efficacy of intraoperative methylene blue (MB) spray in improving the identification and preservation of the recurrent laryngeal nerve (RLN) and parathyroid glands (PGs)…
- Conditions
- Benign Multinodular Goiter, Thyroidectomy, Recurrent Laryngeal Nerve Injury, Hypoparathyroidism
- Trial name
- NCT07395388
- Testing
- Intraoperative topical methylene blue spray, Conventional Dissection
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Services Hospital, Lahore
Surgical Injury
Prophylactic Effects of Esketamine in Surgical Patients
Evidences have showing that esketamine has anti-inflammatory and therapeutic effects on depression and cardiac surgery. The investigators' preliminary results suggest that combined prophylactic and therapeutic use of esketamine…
- Trial name
- NCT05180318
- Testing
- Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato], 0.9% saline
- Where
- China
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Intraoperative Arterial Hypotension
Association of Intraoperative Blood Pressure Excursions Below Cerebral Autoregulatory Boundaries With Organ Injury Following Major Noncardiac Surgery
The aim of study is to investigate the clinical relevance of blood pressure (BP) excursions below cerebral autoregulatory boundaries in major noncardiac surgery.
- Trial name
- AR-NONCARDIAC (NCT05336864)
- Testing
- Non-invasive cerebral oximetry monitoring, additional perioperative blood sampling, clinical & telephone assessments
- Where
- 3 sites in Switzerland
- Volunteers
- 650 people
- Sponsor
- University Hospital, Basel, Switzerland
Delayed Graft Function, Kidney Transplantation
The Impact of Intraoperative Diuretic Use on Delayed Graft Function Following Deceased Donor Renal Transplantation
Delayed graft function, defined as the need for dialysis within seven days of kidney transplantation, is a common complication affecting deceased-donor kidney transplant recipients.
- Trial name
- NCT07726134
- Testing
- Furosemide, Mannitol
- Where
- 2 sites in Canada
- Volunteers
- 160 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Spinal Deformity, Trauma
Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients
Surgical site infections (SSI) are not uncommon, especially in specific high-risk groups including spinal deformity and tumor (i.e. metastatic spine surgery) surgery.
- Conditions
- Spinal Deformity, Trauma, Spinal Tumor, Surgical Site Infection
- Trial name
- NCT03839914
- Testing
- Vancomycin powder
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Brain Damage, Postoperative
Evaluation of Neuronal Damage in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy With Biomarkers
Robotic assisted laparoscopic surgery has become an alternative to open or laparoscopic technique in various surgical fields. Robot assisted laparoscopic surgery is preferred by surgeons and patients due to easy accessibility…
- Conditions
- Brain Damage, Postoperative, Surgery-Complications
- Trial name
- NCT05692804
- Testing
- Mini Mental State Examination(MMSE),Montreal Cognitive Assessment ( MoCA),S100B ( protein S100 subunit beta) ,GFAP ( glial fibrillary acidic protein ),NSE ( neuron-specific enolase )
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Blood Product Transfusion for All Conditions, Trauma
French One Day Survey in 2011 - Knowing Our Population of Labile Blood Products Recipients
Describe the epidemiologic profile and clinical context of transfusion recipients in France. Describe the clinical context of transfusion.
- Conditions
- Blood Product Transfusion for All Conditions, Trauma, Surgical Blood Loss, Hematologic Diseases
- Trial name
- PopReceveur (NCT03313583)
- Testing
- Transfusion of blood products
- Volunteers
- 4,720 people
- Sponsor
- Etablissement Français du Sang
Hypotension, Acute Kidney Injury
A Clinical Decision Support Trial to Reduce Intraoperative Hypotension
The purpose of this study is to provide messages to providers if their patient is at high risk of developing intraoperative hypotension based on past medical history and co-morbidities preoperatively and minutes of hypotension…
- Trial name
- NCT04062994
- Testing
- Nudge to reduce intraoperative hypotension
- Where
- 4 sites in United States
- Volunteers
- 30,000 people
- Sponsor
- University of California, Los Angeles
Aortic Dissection
Effects of Intraoperative Hemoperfusion on Acute Kidney Injury After Aortic Dissection
Acute kidney injury (AKI) is a common and serious complication after aortic dissection (AD), and it is closely related to the inflammatory response associated with cardiopulmonary bypass.
- Trial name
- EIHPOAKIAD (NCT05331495)
- Testing
- Intraoperative Hemoperfusion
- Where
- China
- Volunteers
- 206 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Surgical Site Infections, Stress Hyperglycemia
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
This study is to determine if glucose monitoring and treatment in surgical procedures over 2 hours help to decrease the surgical site infection risk and reduce postoperative complications.
- Trial name
- POGM (NCT06765655)
- Testing
- Insulin Lispro Injection, glucose testing
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- St. Peter's Hospital, Albany, NY
Hip Fractures, Intraoperative Hypotension
Peri-operative Vasopressor Support in Patients Operated for an Acute Hip Fracture (AHF)
The incidence of hypotension perioperatively during operation of an acute hip fracture is unknown. As a surrogate factor the usage of vasopressor support is more adequate as the registration of vasopressor drugs are many times…
- Trial name
- NCT03497949
- Where
- Sweden
- Volunteers
- 997 people
- Sponsor
- Sahlgrenska University Hospital
Spine Fracture
Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery
Reduction of intra-operative blood loss
- Trial name
- NCT05294926
- Testing
- Rocuronium, nerve stimulator
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University