Clinical trials: Intraoperative Injury
Hip Pain Chronic, Hip Impingement Syndrome
Tranexamic Acid (TXA) in Hip Arthroscopy
The primary goal of this study will be to determine if perioperative IV Tranexamic Acid (TXA) administration will reduce intra-operative bleeding and subsequently improve visual clarity during surgery and reduce operative…
- Conditions
- Hip Pain Chronic, Hip Impingement Syndrome, Hip Injuries, Blood Loss
- Trial name
- NCT05710146
- Testing
- Tranexamic acid
- Where
- United States
- Sponsor
- Northwestern University
Quadratus Lumborum Block, Surgical Wound Infiltration
Surgeon Infiltration QL Block Comparison
The purpose of this study is to learn if using a Quadratus Lumborum (QL) plane injection technique (also called a "nerve block") that numbs the nerves going to the abdominal area improve pain control after surgery compared to…
- Trial name
- NCT03496610
- Testing
- Liposomal Bupivicaine, QL Block
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
Surgical Injury
Surgical Planning With Patient-specific Pancreaticobiliary Disease With 3D Models
Background: Three-dimensional (3D) printing has been increasingly used in medical applications with the creation of accurate patient-specific 3D printed models in medical imaging data.
- Trial name
- NCT04410640
- Testing
- survey
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Ege University
Post-operative Cognitive Dysfunction
Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly
BACKGROUND: Post-operative cognitive dysfunction (POCD) is a potentially irreversible loss of brain functions observed in elderly patients after surgical operations under general anaesthesia.
- Trial name
- THE BRIDGE (NCT02428062)
- Testing
- Hemodynamic target, Phenylephrine, Intravenous fluids
- Where
- Italy
- Volunteers
- 1,812 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Chronic Subdural Hematomas
Middle Meningeal Artery Coagulation During Burr-Hole Drainage for Chronic Subdural Haematoma (BURR-MMA)
Chronic subdural haematoma (cSDH) is a common condition in older adults, usually treated by burr-hole surgery to drain the collection.
- Trial name
- BURR-MMA (NCT07549893)
- Testing
- CT-Guided Intra-Operative Middle Meningeal Artery Interruption
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
Hypotension, Postoperative Complications
Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery
Major adverse cardiovascular events (MACE) are a leading cause of serious complications and death following major noncardiac surgery.
- Conditions
- Hypotension, Postoperative Complications, Acute Coronary Syndrome, Heart Failure
- Trial name
- BBB (NCT02533128)
- Testing
- Liberal blood pressure management, Tight blood pressure management
- Where
- Switzerland
- Volunteers
- 458 people
- Sponsor
- Miodrag Filipovic, Prof. Dr. med.
Perforated Eardrum
Inhalational Anesthesia vs TIVA in Endoscopic Tympanoplasty
This study aims to prospectively compare surgical field quality and intraoperative blood loss between general inhalational anesthesia to total intravenous anesthesia (TIVA) alone in subjects undergoing endoscopic ear surgery.
- Trial name
- TIVA (NCT05993039)
- Testing
- Isoflurane Inhalant Product, Sevoflurane inhalant product, Propofol injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Our Lady of the Lake Hospital
Pelvic Fracture, Transfusion Reaction
Blood Transfusion Among Patients With Pelvic Fracture in China
According to the patient's blood management concept, this study intends to collect basic information, surgical data, blood transfusion related data and patient prognosis data of patients with pelvic fractures, and to construct a…
- Conditions
- Pelvic Fracture, Transfusion Reaction, Blood Transfusion Complication
- Trial name
- PBM (NCT03855644)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Hypothermia
Local CO2 Increases Core and Wound Temperature
Eighty adult patients undergoing open colon surgery will be randomized to either:standard warming measures or to additional insufflation of humidified carbon dioxide in the open wound cavity during major abdominal surgery.
- Trial name
- NCT01213628
- Testing
- humidified warmed CO2
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Perioperative Cardiavascular Complication, Peroperative Complication
Perioperative Management of Risk Factors in the Elderly Patients
In 2017, the number of operations on hospitalized patients in China was more than 57 million, of which more than 20 million were performed on elderly patients (≥65 years of age).
- Conditions
- Perioperative Cardiavascular Complication, Peroperative Complication, Perioperative Pulmonary Complication, Perioperative Neurological Complication
- Trial name
- NCT04967872
- Testing
- Implementing risk management and control plan for the elderly during perioperative period
- Where
- China
- Volunteers
- 4,782 people
- Sponsor
- Ailin Luo
Ureteral Injury
Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets
Recently, Indigo Carmine and Methylene Blue have been the standard agents to visualize ureteral jets during intraoperative cystoscopy.
- Trial name
- NCT03432572
- Testing
- Pyridium, Riboflavin, Thiamine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Pilonidal Disease
Intraoperative Wound Irrigation for Pilonidal Disease
The purpose of this study is to determine the best method for cleaning wounds during surgery for patients with Stage 3 pilonidal disease.
- Trial name
- NCT07417202
- Testing
- Hypochlorous Acid
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Stanford University
Acute Lung Injury
A Trial to Evaluate the Impact of Lung-protective Intervention in Patients Undergoing Esophageal Cancer Surgery
The purpose of this trial is to determine whether low tidal volume during intraoperative one-lung ventilation could decrease the incidence rate of postoperative acute lung injury compared to "normal" tidal volume.
- Trial name
- NCT01194895
- Testing
- protective ventilation, conventional ventilation
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Shanghai Zhongshan Hospital
Distal Radius Fractures, Poor Bone Quality
The Influence of Local Bone Status on Complications After Surgical Treatment of Distal Radius Fractures
The purpose of this study is to evaluate if poor bone quality increases the risk of specific types of treatment complications in patients with distal radius fractures treated with open reduction and Locking Compression…
- Conditions
- Distal Radius Fractures, Poor Bone Quality, Treatment Complications
- Trial name
- NCT01144208
- Where
- 11 sites in United States, Austria and 4 more
- Volunteers
- 244 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Hip Injuries and Disorders, Hip Arthrosis
Diagnostic Performance of 3T MRI T2 Mapping Technique in Chondro-labral Pathology of the Hip, Correlated With Intraoperative Arthroscopic Findings: Interventional Diagnostic Technique Validation Study (HPI MRI 3T)
The goal of this observational study is to evaluate the diagnostic performance of the T2 mapping technique of the following 4 MRI scans in detecting hip chondro-labral lesions in comparison with intraoperative arthroscopic…
- Trial name
- NCT06067243
- Testing
- T2 mapping 3T MRI + hip arthroscopy
- Where
- Italy
- Sponsor
- Istituto Ortopedico Rizzoli
Fracture Neck of Femur
Internal Fixation of Hip Fractures Using Intraoperative Simultaneous Two Axis View
Hip fractures are one of the most frequent operated fractures procedures in orthopedics, with a world wide annual incidence of approximately 1.7 million. These fractures are associated with substantial morbidity and mortality.
- Trial name
- NCT01524718
- Testing
- Imaging with two X-ray image intensifiers
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Burns
Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients
This study aim to determine whether a small-dose esketamine infusion can be used for pain control in severe burn patients, and thereby reduce the total intra-operative opioid requirement.
- Trial name
- NCT04682782
- Testing
- Esketamine, Saline
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burns, Hand Injuries
Range of Motion Following Intraoperative Coban Dressing Application in Hand Burns
Participants of this study will include burns requiring skin graft to hand(s). After informed consent, an occupational therapy evaluation will be performed.
- Trial name
- NCT01027520
- Testing
- application of coban dressing
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Rotator Cuff Tears
Prospective Analysis of Intraoperative AMNIOGEN® Injection in Patients With Rotator Cuff Tear
Purpose: The purpose of this article is to examine the clinical application of AMNIOGEN® in patients with rotator cuff tear. Methods: The study was conducted on 100 adult participants with age over affected by unilateral shoulder…
- Trial name
- NCT04599673
- Testing
- AMNIOGEN, normal saline
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Graft Failure
Intraoperative NIRS of Transplanted Kidney for Prediction of Acute and Sub-acute Injury
This is a prospective, observational cohort study, designed to explore the use of NIRS in kidney transplants. This study will investigate an association between measurements of intra- operative NIRS and post - operative graft…
- Trial name
- NCT04685174
- Testing
- Invos Model 5100C Cerebral/Somatic Oximeter
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center