Clinical trials: Intraoperative Injury
Head and Neck Surgery, Maxillofacial Surgery
Impact of Nociception Level (NOL)-Guided Remifentanil Infusion on Intraoperative Arterial Pressure and Vasopressor Necessity
The aim of this study is to determine if Nociception Level (NOL)-guided Remifentanil analgesia, combined with Entropy-guided Propofol anesthesia, has a significant beneficial effect on the incidence of intraoperative hypotension…
- Trial name
- NCT04963036
- Testing
- Entropy and NOL-Guided Goal Directed Anesthesia, Standard of Care Group (Entropy and blinded NOL)
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Postoperative Acute Kidney Injury
Intraoperative Renal Desaturation and Postoperative Acute Kidney Injury
The aim of this study is to investigate the changes in renal regional oxygen saturation (rSO2) monitored by near-infrared spectroscopy (NIRS) and its relationship with the occurrence of postoperative AKI.
- Trial name
- NCT04967105
- Testing
- Near-infrared spectroscopy
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Chinese PLA General Hospital
Peritonitis
Lavage With Super-Oxidized Solution for Secondary Peritonitis
Secondary peritonitis is a frequent abdominal emergency that is still associated with a high morbidity and mortality rate due to surgical site infections (SSI) and sepsis.
- Trial name
- SOSPeritonitis (NCT05050253)
- Testing
- Super-oxidized solution (SOS), Ringer's solution
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Wound Complications
Effect of Intra-operative Glove-changing During Cesarean Section on Post-op Complications: A Randomized Controlled Trial
A randomized controlled trial to determine whether changing of gloves by the surgical team during cesarean section may decrease post-operative infectious morbidity and wound complications
- Trial name
- NCT02907892
- Testing
- Glove change
- Where
- United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Red Blood Cells Transfusion
The Effect of Red Blood Cells Storage Duration on Biochemical Changes in Pediatric Patients
The aim of the study is to detect if the storage duration of red blood cells has impact on some biochemical parameters after intra operative transfusion in pediatric trauma patient
- Trial name
- NCT02724605
- Testing
- Red blood cells unit age 14 days or less, Red blood cells unit age more than 14 days
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Abdelrady S Ibrahim, MD
Spine Disease, Neurological Disorder
EMG and SSEP Device (EPAD® 2.0) for Intraoperative Monitoring of Patient Undergoing Spinal Nerve Spine Surgery
In patients undergoing spine surgery, spinal nerve roots and spinal cord are vulnerable to surgical insults especially for instrumentation and may lead to long term sequelae.
- Trial name
- NCT03848377
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Scars
The Effects of Fractional Carbon Dioxide (CO2) Laser Treatment Prior to Wound Closure
The purpose of this study is to determine if fractional carbon dioxide laser treatment of a fresh wound at the time of surgery, decreases scar formation. Scar revision is commonly done at 6-10 weeks following surgery.
- Trial name
- NCT00969475
- Testing
- Lumenis fractional carbon dioxide laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Moy-Fincher Medical Group
Rotator Cuff Injuries, Anesthesia, General
Comparison of Two General Anesthesia Maintenance Strategies on Intraoperative Visibility During Arthroscopic Rotator Cuff Surgery: A Randomized Trial
Shoulder arthroscopy is one of the most common orthopedic procedures, and the quality of the surgeon's view inside the joint is critical to its safety and success.
- Conditions
- Rotator Cuff Injuries, Anesthesia, General, Arthroscopy
- Trial name
- CLEAR-SHOULDER (NCT07628244)
- Testing
- Inhalation anesthesia, Continuous intravenous anesthesia
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Tonsil; Injury, Surgical Blood Loss
Hemostasis Using Surgicel in Pediatric Tonsillectomy
Tonsillectomy is one of the commonest procedures performed in otolaryngology and one of its major complications is post-tonsillectomy bleeding.
- Trial name
- NCT03984851
- Volunteers
- 203 people
- Sponsor
- Dr. Abdul Mohsen Ibrahim Al-Turki Clinic
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Gallstone, Gallstone; Cholecystitis, Acute
Indocyanine Green Fluorescence During Fundus First Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the routine method for managing gallstone disease. This is considered a safe procedure with low risk of severe complications.
- Trial name
- INFUNDUS (NCT06918210)
- Testing
- Indocyanine Green, Cholangiography
- Volunteers
- 294 people
- Sponsor
- Karolinska Institutet
Spine Fusion, Spine Injury
Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate the Feasibility of Developing a Markerless Tracking System for Spine Surgery.
The primary study objective is to build a video dataset, consisting of both colour and depth information, of spine surgery that includes both 'open' and 'minimally invasive' (MIS) surgeries.
- Conditions
- Spine Fusion, Spine Injury, Spine Degeneration, Navigation, Spatial
- Trial name
- SPIVOS (NCT06580379)
- Testing
- Spine surgery
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Postoperative Acute Kidney Injury, Intraoperative Hypotension
Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis
Postoperative acute kidney injury (AKI) is a serious complication often linked to low blood pressure during surgery. This study aims to better protect patients' kidneys by personalizing how blood pressure is managed during an…
- Trial name
- NCT07156474
- Where
- China
- Volunteers
- 44,504 people
- Sponsor
- Lanyue Zhu
Liver Transplantation, Surgical Site Infection
Surgical Site Infections After Liver Transplantation Based on Perioperative Antibiotics
This study will be to prospectively determine differences in Surgical Site Infection (SSI) if a prolonged course of post-operative antibiotics are used following liver transplantation.
- Trial name
- NCT02717273
- Testing
- standard, extended, liver transplant
- Volunteers
- 102 people
- Sponsor
- University of Virginia
Acute Cervical Spinal Cord Injury
Safety and Efficacy of Cethrin® in Adult Subjects With Acute Cervical Spinal Cord Injury
This is a multicenter, randomized, double-blind, placebo-controlled, Phase IIb study to be conducted in North America and Europe and will include male and female subjects with acute cervical SCI, 18 to 62 years of age, who…
- Trial name
- NCT00610337
- Testing
- Cethrin® (BA-210)
- Sponsor
- BioAxone BioSciences, Inc.
Ventilator-induced Lung Injury
Intraoperative Lung-Protective Ventilation in Neurosurgery
The purpose of this study is to explore the effectiveness of lung-protective ventilation during general anesthesia for neurosurgical procedures on postoperative pulmonary outcome, compared with traditional ventilation.
- Trial name
- NCT02386683
- Testing
- lung-protective ventilation
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Capital Medical University
Myocardial Infarction Postoperative, Myocardial Injury
Intraoperative Hypotension and Perioperative Myocardial Injury
Acute myocardial infarction (MI) is a significant complication following non-cardiac surgery. We sought to evaluate incidence of perioperative MI, its preoperative - and intraoperative - risk factors and outcomes after this…
- Conditions
- Myocardial Infarction Postoperative, Myocardial Injury, Intraoperative Complications, Intraoperative Hypotension
- Trial name
- NCT03974321
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Postoperative Pain
Intraoperative Local Anaesthetic and Postoperative Pain
Background: Intraoperative wound infiltration with local anaesthetic is commonly used. Apart from the obvious immediate action it has been supported that a possible down regulation of pain receptors may lead to longer effects.
- Trial name
- Pain-1 (NCT02171299)
- Testing
- Wound infiltration with local anaesthetic, Ropivacaine
- Where
- Greece
- Volunteers
- 400 people
- Sponsor
- Hellenic Red Cross Hospital
Femoral Neck Fractures, Hemiarthroplasty
Efficacy of Intraoperative Periarticular Injections in Hip Fracture Hemiarthroplasty
The objective of this study was to assess the effectiveness of the intraoperative periarticular solution in reducing blood loss and minimizing transfusion requirements in patients with femoral neck fractures who underwent…
- Conditions
- Femoral Neck Fractures, Hemiarthroplasty, Blood Loss Requiring Transfusion
- Trial name
- NCT06701695
- Testing
- Periarticular Injection (PAI), Control (Standard treatment)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Hypotension, ENT Disease
Influence of the "Hypotension Probability Index" on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery
The aim of the project is to investigate whether the use of the HPI can reduce the number and duration of intra- and postoperative hypotension in ventilated patients during and two hours after extensive surgery in the head and…
- Conditions
- Hypotension, ENT Disease, Acute Kidney Injury, Anesthesia
- Trial name
- NCT04151264
- Testing
- Hypotension probability index (HPI)
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- University of Giessen