Clinical trials: Intraoperative Ventilation
Smoking, Oxygen Deficiencies
The Effects of Secondary Smoking During One Lung Ventilation
Smoking and perhaps secondary smoking is associated with many perioperative and postoperative complications, especially respiratory events. Hypoxemia and airway damage can be associated with secondary smoking.
- Trial name
- NCT03006224
- Testing
- One Lung Ventilation
- Volunteers
- 60 people
- Sponsor
- Inonu University
Video Assisted Thoracic Surgery (VATS), Postoperative Complications
Clinical Effects of Intraoperative Heat and Moisture Exchange Systems During Thoracic Surgery: A Prospective Observational Cohort Study
General anesthesia with endotracheal intubation bypasses the physiological warming and humidification functions of the upper airway, allowing cold and dry gases to reach the lower respiratory tract.
- Conditions
- Video Assisted Thoracic Surgery (VATS), Postoperative Complications, Pulmonary Complications in Surgical Patients, Humidification
- Trial name
- NCT07729319
- Testing
- Active Heated Humidification, Heat and Moisture Exchanger
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
Lung Protective Ventilation, Intraoperative Ventilation
Cohort Study of Intraoperative Lung Protective Ventilation Trends in a Large Canadian Health Authority
The goal of this observational study is to ascertain the practice patterns and predictors in performing lung protective ventilation as per clinical guidelines for adult patients undergoing non-cardiac surgery in Fraser Health…
- Conditions
- Lung Protective Ventilation, Intraoperative Ventilation, COVID, COVID - 19
- Trial name
- NCT06821139
- Where
- Canada
- Volunteers
- 28,700 people
- Sponsor
- Perseus Missirlis
Ventilator-Induced Lung Injury, Ventilator Lung
How To Prevent Ventilator-Related Lung Damage in Intraoperative Mechanical Ventilation? Pcv or Vcv ?
Introduction: Intraoperative Mechanical Ventilation practices can lead to ventilator-associated lung injury (VILI) and postoperative pulmonary complications in healthy lungs.
- Conditions
- Ventilator-Induced Lung Injury, Ventilator Lung, Mechanical Ventilation Complication, Postoperative Complications
- Trial name
- NCT05814081
- Testing
- Position/Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Mechanical Ventilation Complication
Effect of Intraoperative PEEP Individualization According to Driving Pressure in Major Abdominal Surgery
In this prospective, randomized trial, including patients scheduled for a major open or laparoscopic abdominal surgery (duration >2 hours) under general anesthesia , the investigators will compare 2 strategies of protective…
- Trial name
- NCT05781373
- Testing
- Peep individualization
- Volunteers
- 100 people
- Sponsor
- Mongi Slim Hospital
Intraoperative Lung Protective Ventilation
Intraoperative Lung Protective Ventilation in Czech Republic
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic.
- Trial name
- IOLPVCZ (NCT07282899)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Blood Loss, Surgical
Effect of Equal Ratio Ventilation on Blood Loss During Posterior Lumbar Interbody Fusion Surgery
Ventilator mode change was associated with decrease in blood loss during posterior lumbar interbody fusion (PLIF) due to decrease in the peak inspiratory pressure (PIP).
- Trial name
- NCT03030963
- Testing
- Equal ratio ventilation(ERV), I:E Ratio "1:2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Major Abdominal Surgeries, Mechanical Ventilation
Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study
This study will include patients aged 50 and older scheduled for elective abdominal oncologic surgery, classified as ASA II and III due to increased anaesthetic and surgical risk. Gender will not be a stratification factor.
- Trial name
- IMMEDIUM (NCT07339449)
- Testing
- Multimodal monitoring
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Dubrava
Cough, Thoracic Surgery
Effects of Intraoperative Vagal Block on Reducing the Postoperative Cough After Thoracic Surgery
Randomized controlled study to investigate the role of intraoperative vagal nerve block for preventing the postoperative cough in patients who received the pulmonary resection for lung cancer
- Conditions
- Cough, Thoracic Surgery, Nerve Block
- Trial name
- NCT04672694
- Testing
- Vagus nerve block, No vagus nerve block
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Severance Hospital
Respiratory Failure, Acute Respiratory Failure Requiring Intubation
Intra-operative Inspiratory Oxygen Fraction and Postoperative Respiratory Complications
Respiratory complications represent the second most frequent type of postoperative complications with an incidence estimated to range from 2.0% to 7.9% It has been shown that intra-operative protective ventilation is associated…
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Intubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02399878
- Testing
- Inspiratory oxygen
- Volunteers
- 70,000 people
- Sponsor
- Massachusetts General Hospital
Deep Sedation, Non-invasive Ventilation Support
Comparison of Nasal Continuous Positive Airway Pressure (CPAP) Mask and Nasal Airway in Molar Tooth Extraction Under Deep Sedation
In patients with high levels of fear and anxiety, it is recommended to perform dental procedures under sedation or general anesthesia depending on the nature of the procedure.
- Conditions
- Deep Sedation, Non-invasive Ventilation Support, Nasal Airway, Nasal CPAP Mask
- Trial name
- NCT06436638
- Testing
- Non-invasive ventilation support equipment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gözde Nur Erkan
Ventilator-Induced Lung Injury
Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA
Lung protective ventilation (LPV) has been proposed to reduce the incidence of postoperative pulmonary complications (PPCs), and protect against ventilator induced lung injury (VILI).
- Trial name
- NCT03135691
- Where
- United States
- Sponsor
- Ohio State University
Intraoperative Hypotension
Hypotension Prediction Index (HPI) in Lung Resections
Perioperative hypotension is a risk factor for perioperative complications. Advances in machine learning and artificial intelligence have produced an algorithm that predicts the occurrence of hypotension episodes by analyzing an…
- Trial name
- NCT06202638
- Testing
- HemoSphere monitor with Acumen Hypotension Prediction Index Software
- Where
- 3 sites in Greece, Poland
- Volunteers
- 77 people
- Sponsor
- John Paul II Hospital, Krakow
Cough
Effect of Bronchial Artery Protection on Cough After Thoracoscopic Lobectomy
The postoperative complications of thoracoscopic radical surgery for lung cancer mainly include postoperative bleeding, pulmonary infection, chylothorax, nerve injury, pulmonary embolism, arrhythmia, postoperative cough…
- Trial name
- NCT04651686
- Testing
- Preoperative three-dimensional reconstruction and intraoperative protection of bronchial artery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Posterior Spinal Fusion
Changes in Cerebral Oxygenation Based on Intraoperative Ventilation Strategy
The proposed research aims to investigate how different ventilation strategies may affect cerebral tissue oxygenation in the pediatric population.
- Trial name
- NCT02651103
- Testing
- NIRS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joseph D. Tobias
Obesity, Surgery
Effect of Transpulmonary Pressure Guided Ventilation on Intraoperative Right Heart Function
The purpose of this clinical trial is to determine whether different types of ventilator settings during surgery change the relationship between the pressures in the lungs and the function of the heart.
- Conditions
- Obesity, Surgery, Anesthesia, Echocardiography, Transesophageal
- Trial name
- NCT05709041
- Testing
- Individualized lung-protective ventilation, Standard lung-protective ventilation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Vermont Medical Center
Obesity, Mechanical Ventilation Pressure High
Evaluation of Regional Lung Mechanics in Obese Patients Undergoing Laparoscopic Surgery
This study will evaluate what is the impact of laparoscopy and Trendelenburg position on lung regional ventilation distribution in obese patients, focusing on the differences between the different phases of surgery.
- Conditions
- Obesity, Mechanical Ventilation Pressure High, Intraoperative Respiratory Injury
- Trial name
- OBESE-EIT (NCT05554536)
- Testing
- PEEP titration trial
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Università degli Studi di Ferrara
Tonsillitis Chronic, Tonsillitis Recurrent
The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.
The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
- Conditions
- Tonsillitis Chronic, Tonsillitis Recurrent, OSA - Obstructive Sleep Apnea
- Trial name
- NSAIDs (NCT07035314)
- Testing
- Dexamethasone, NSAIDs, Control (Standard treatment)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Aspiration, Respiratory
Continuous Supraglottic pH Monitoring in Prolonged Intubated Intensive Care Patients and High Risk Aspiration Intraoperative Patients
This is a pilot prospective cohort study of the incidence of supraglottic pH readings.
- Trial name
- NCT02604043
- Testing
- pH monitoring, accelerometer monitoring
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University
Surgery, Mechanical Ventilation Pressure High
Accuracy of the Set Tidal Volume During Intraoperative Mechanical Ventilation
Prior to surgery the anesthesia team will be putting a breathing tube into the patient's windpipe and attaching it to a mechanical ventilator (breathing machine).
- Trial name
- NCT06232915
- Testing
- Mechanical ventilation
- Where
- United States
- Sponsor
- Joseph D. Tobias