Clinical trials: Intrapartum Fever
Pregnancy
Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?
Epidural techniques offer the advantage of being able to titrate the level, density, and duration of the blockade through the use of a catheter and are associated with relative maternal hemodynamic stability.
- Trial name
- matvent (NCT02339389)
- Testing
- Labor analgesia
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Brigham and Women's Hospital
Epidural Related Maternal Fever, Analgesia, Epidural
The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever
This study investigates how the temperature of local anesthetics affects maternal fever related to epidural analgesia during childbirth.
- Conditions
- Epidural Related Maternal Fever, Analgesia, Epidural, Fever, Intrapartum Fever
- Trial name
- NCT06682416
- Testing
- In the context of epidural analgesia, the temperature of the local anesthetic solution is elevated to 37°C utilizing a blood transfusion and infusion warmer.
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Intrapartum Fever
Machine Learning to Predict Fever After Labor Analgesia
Post-labor analgesia intrapartum fever (PAIF) is a serious complication that increases the risk of cesarean delivery, postpartum bleeding, and health problems for newborns.
- Trial name
- NCT07880665
- Testing
- Labor analgesia
- Volunteers
- 6,144 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Pyrexia, Abdominal Delivery
Combined Anesthesia for Labor and Maternal Temperature
Maternal intra-partum fever commonly complicates the process of labour. Its occurrence is often regarded as being synonymous with the presence of chorioamnionitis.
- Trial name
- feveranalg (NCT01078519)
- Testing
- Combined epidural and spinal anesthesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Fever
Evaluation of Fever Occurring in Labor in Patients Receiving Epidural Anesthesia
Briefly, the investigators propose to evaluate nulliparous (first time mothers) patients beyond 36 0/7 weeks' gestation in active labor who already have received epidural anesthesia and have an intrauterine pressure catheter…
- Trial name
- NCT00326521
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Intrapartum Fever, Chorioamnionitis
Antipyretic Treatment for Intrapartum Fever: Dipyrone vs Acetaminophen (RCT)
Chorioamnionitis, or intraamniotic infection, is a common condition affecting 2-5% of all term births. This condition poses well-recognized maternal and neonatal risks, and entails a series of clinical management decisions…
- Trial name
- PARADIP (NCT06950840)
- Testing
- Acetaminophen, dipyrone
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- Wolfson Medical Center
Obstetric Labor Complications, Fever
Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia
This study aims to explore the effect of intravenous vitamin C infusion on intrapartum fever after epidural labor analgesia, to reduce the impact of intrapartum fever on maternal and infant, improve maternal and infant outcomes…
- Trial name
- EIVCIMFAELA (NCT06354582)
- Testing
- Vitamin C Injection, Normal saline
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kunyue Li
Intrapartum Fever
Intranasal Dexmedetomidine for Prevention of Intrapartum Fever
Brief Title: Intranasal Dexmedetomidine for Prevention of Intrapartum Fever This study aims to evaluate the effect of intranasal dexmedetomidine (Dex) administered before neuraxial labor analgesia on the incidence of intrapartum…
- Trial name
- NCT07501221
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 446 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Fever, Oxidative Stress
Reduction of Intrapartum Fever With Intravenous Acetaminophen
The investigators plan to administer acetaminophen (Tylenol) for the treatment of fever in laboring patients by either an oral or intravenous (IV) route.
- Trial name
- RIFIVA (NCT02625454)
- Testing
- Intravenous Acetaminophen, Oral Acetaminophen
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Richmond University Medical Center
Pregnancy Related, Fever
Assessment of Labour Progress by Intrapartum Ultrasound
Assessment of labor progress via digital exams is considered the standard of care in most delivery rooms. However, this method can be stressful, painful and imprecise and multiple exams increase the risk for chorioamnionitis.
- Conditions
- Pregnancy Related, Fever, Chorioamnionitis, Labor Complication
- Trial name
- NCT04651309
- Testing
- Transperineal Ultrasound
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Epidural Analgesia, Analgesic Effect
Epidural Analgesia and Maternal Fever During Labor
Women who receive epidural analgesia during labor are more likely to develop fever than those who do not. Maternal fever during labor can produce various harmful effects on both mothers and infants.
- Conditions
- Epidural Analgesia, Analgesic Effect, Fever
- Trial name
- NCT04940091
- Testing
- Epidural analgesia
- Where
- 8 sites in China
- Volunteers
- 1,051 people
- Sponsor
- Peking University First Hospital
Chorioamnionitis, Intrapartum Fever
Intrapartum Fever: Antibiotics Versus no Treatment
The purpose of this study is to determine whether antibiotics can be safely avoided in women who develop a fever during labor. Because investigators have no accurate tests to determine whether women who develop fever during labor…
- Conditions
- Chorioamnionitis, Intrapartum Fever, Intra-amniotic Infection
- Trial name
- NCT03168178
- Testing
- Standard Antibiotic Treatment, No Antibiotic Treatment
- Where
- United States
- Sponsor
- University of Utah
Histological Placental Inflamation With or Without Fever
Intrapartum Fever and Histopathological Placental Findings
Intrapartum fever associated with epidural anesthesia is caused by non infectious causes therefore without histological findings
- Trial name
- NCT01175187
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Vaginal Delivery
The Effects of Combined Spinal Epidurals on Fever During Labor of First-Time Mothers
The purpose of this study is to determine if the epidural of local anesthetics has an effect on fever that may occur in first time mothers during labor.
- Trial name
- CSE (NCT00802646)
- Testing
- saline, fentanyl/bupivacaine/epinephrine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled
Maternal Glucose, Cortisol, and Neonatal Outcomes With and Without GDM
This study will compare maternal blood glucose and cortisol responses and neonatal outcomes between women with gestational diabetes mellitus and women without gestational diabetes mellitus who receive epidural analgesia during…
- Trial name
- NCT07870629
- Where
- 3 sites in Vietnam
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Intrapartum Maternal Fever, Clinical Chorioamnionitis
Association Between Neuraxial Labor Analgesia and Maternal and Neonatal Infectious Outcomes
The goal of this retrospective observational cohort study is to explore the associations between neuraxial labor analgesia and maternal-neonatal infectious outcomes among women attempting vaginal delivery, and to distinguish…
- Conditions
- Intrapartum Maternal Fever, Clinical Chorioamnionitis, Neonatal Infection
- Trial name
- NCT07751666
- Testing
- neuraxial labor analgesia
- Volunteers
- 49,000 people
- Sponsor
- Peking University First Hospital