Clinical trials: Intrathecal Dexmedetomidine
Intrathecal Dexmedetomidine
This Study Aims to Determine Whether Lower Doses (4 µg) of Intrathecal Dexmedetomidine Can Provide Comparable Analgesic Benefits While Minimizing Adverse Hemodynamic Effects in Patients Encountered in Our Setup( Shifa International Hospital Islamabad).
This study aims to determine whether lower doses (4 µg) of intrathecal dexmedetomidine can provide comparable analgesic benefits while minimizing adverse hemodynamic effects in patients encountered in our setup( Shifa…
- Trial name
- NCT07807020
- Testing
- Intrathecal Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Intrathecal Morphine, Intrathecal Dexmedetomidine
Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries
This study aims to compare the efficacy of intrathecal morphine and intrathecal dexmedetomidine in reducing pain following lumbar spine fixation surgeries.
- Conditions
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Placebo, Postoperative Pain
- Trial name
- NCT07777627
- Testing
- Intrathecal Morphine, Intrathecal Dexmedetomidine, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Intrathecal Dexmedetomidine, Bupivacaine
Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic Surgery
This study aims to compare the duration of analgesia (as the primary outcome) and adverse effects (as the secondary outcome) after intrathecal administration of dexmedetomidine with hyperbaric bupivacaine to patients undergoing…
- Conditions
- Intrathecal Dexmedetomidine, Bupivacaine, Knee Orthopedic Surgery
- Trial name
- NCT07522736
- Testing
- Dexmedetomidine 4 μg, Dexmedetomidine 8 μg, Dexmedetomidine 12 μg
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Intrathecal, Dexmedetomidine
Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity
The current work evaluated whether the combination of intrathecal dexmedetomidine and fentanyl provides superior postoperative analgesia to fentanyl alone when administered with hyperbaric bupivacaine.
- Conditions
- Intrathecal, Dexmedetomidine, Fentanyl, Bupivacaine
- Trial name
- NCT07276867
- Testing
- Fentanyl + Dexmedetomidine, Fentanyl
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- National Cancer Institute, Egypt
Transversalis Fascia Plane Block, Intrathecal Dexmedetomidine
Transversalis Fascia Plane Block Versus Intrathecal Dexmedetomidine in Patients Undergoing Cesarean Section
This study aims to compare the analgesic efficacy of the transversalis fascia plane (TFP) block and intrathecal dexmedetomidine in patients undergoing cesarean section (CS).
- Conditions
- Transversalis Fascia Plane Block, Intrathecal Dexmedetomidine, Cesarean Section
- Trial name
- NCT07170267
- Testing
- Transversalis fascia plane block, Intrathecal dexmedetomidine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Intrathecal Dexmedetomidine, Adductor Canal Block
Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty
The aim of this work is to evaluate the effect of combined intrathecal dexmedetomidine and adductor canal block for analgesia after total knee arthroplasty (TKA).
- Conditions
- Intrathecal Dexmedetomidine, Adductor Canal Block, Analgesia, Total Knee Arthroplasty
- Trial name
- NCT06837844
- Testing
- Intrathecal Dexmedetomidine, Adductor Canal Block, Intrathecal Dexmedetomidine + Adductor Canal Block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Kafrelsheikh University
Dexmedetomidine, Intrathecal
Dexmedetomidine as an Intrathecal Adjuvant to Hyperbaric Bupivacaine for Postoperative Analgesia in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction Surgeries
This study aimed to evaluate the effect of adding low doses of dexmedetomidine to hyperbaric bupivacaine during spinal anesthesia on post operative analgesia characteristics in Arthroscopic Anterior Cruciate Ligament…
- Conditions
- Dexmedetomidine, Intrathecal, Adjuvant, Hyperbaric Bupivacaine
- Trial name
- NCT06667024
- Testing
- Hyperbaric bupivacaine, Dexmedetomidine and Hyperbaric bupivacaine
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Tanta University
Intrathecal Morphine, Intrathecal Morphine-dexmedetomidine Combination
Intrathecal Morphine Versus Morphine-dexmedetomidine Combination for Postoperative Pain Control After Total Knee Replacement
Total knee replacement is one of the most painful orthopedic surgical procedures. Patients who undergo total knee replacement are usually older and have limited cardiac and pulmonary reserves.
- Conditions
- Intrathecal Morphine, Intrathecal Morphine-dexmedetomidine Combination, Postoperative Pain Control, Total Knee Replacement
- Trial name
- NCT05439564
- Testing
- Dexmedetomidine, Morphine
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tanta University
Intrathecal Dexmedetomidine
Intrathecal Dexmedetomidine to Decrease Postoperative Nausea and Vomiting and Shivering.
Background: Highly selective α-2 agonist dexmedetomidine in increasingly used as an intrathecal adjuvant for caesarean section performed under subarachnoid block.
- Trial name
- NCT05892705
- Testing
- Dexmedetomidine Injection [Precedex]
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dexmedetomidine, Transurethral Resection of Prostate
Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the Prostate
This study is to evaluate The analgesic effect of intrathecal versus intravenous dexmeditomedine in transurethral resection of the prostate
- Conditions
- Dexmedetomidine, Transurethral Resection of Prostate, Intravenous, Intrathecal
- Trial name
- NCT04618965
- Testing
- control group, Intrathecal dexmedetomidine, Intravenous dexmedetomidine
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Intrathecal Dexmedetomidine, Pediatric Cancer Surgery
Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine in Children Undergoing Major Abdominal Cancer Surgery
In this study the investigators aim to determine the analgesic effect and side effects of intrathecal fentanyl and dexmedetomidine as adjuvant to local anesthetics in pediatric patients undergoing major abdominal cancer surgeries.
- Trial name
- NCT02861716
- Testing
- Bupivacaine, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute