Clinical trials: Intrauterine Device
Contraceptive Usage, Bleeding Due to Intrauterine Contraceptive Device
Acceptability and Continuation Rate of Implanon in a Brazilian Public Sector
The main side-effect of Implanon is the changes induces in bleeding patterns including amenorrhea, infrequent to irregular bleeding and frequent and prolonged bleeding; without any previous symptom and it was characterized as…
- Trial name
- NCT01392157
- Testing
- copper-releasing intrauterine device, ENG-releasing implant, LNG-releasing intrauterine system
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
IUD Insertion
Vaginal Vs Subling Misoprost Before Iud Insertion in Women With Previous CS
Insertion failures of intrauterine devices and cervical problems seem to occur more often among women who have never delivered vaginally.
- Trial name
- NCT05204979
- Testing
- Vaginal Versus Sublingual misoprostol
- Where
- Egypt
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
A Trial of 2% Lidocaine Gel for Intrauterine Device (IUD) Insertion
The intrauterine device (IUD) is a long-acting, highly effective, reversible contraceptive that may be underutilized due to fear of pain during insertion.
- Trial name
- NCT01292447
- Testing
- 2% lidocaine gel
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Contraception
A Novel IUD Insertion Technique
A previous trial performed by our research team, in order to reduce the pain associated with intrauterine device insertion, compared the novel technique of IUD insertion under the guidance of the trans-abdominal sonography to the…
- Trial name
- NCT02582268
- Testing
- intrauterine device TCu 380A, Trans-abdominal sonography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Contraception
Patient-Applied Pretreatment Analgesia for Intrauterine Device Placement
The goal of this clinical trial is to perform a pilot study looking at the benefit of topical anesthetic application to the cervix by tampon prior to intra-uterine device insertion.
- Trial name
- PAP-AID (NCT05890495)
- Testing
- Lidocaine topical, Tampon
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
IUD Insertion Complication, Acute Pain
LI4 Acupuncture for Analgesia in Intrauterine Device Insertion
Pain during IUD insertion is substantially psychologic in origin, responds extremely well to non-pharmacologic interventions. Considering the fact that acupuncture is a modality exerting both psychologic and physiologic effects…
- Trial name
- NCT04963582
- Testing
- Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Pain
Cervical Lidocaine for Intrauterine Device Insertion Pain
The aim of this study is to evaluate intracervical lidocaine gel as a means to decrease pain associated with intrauterine device (IUD) insertion.
- Trial name
- CLIIP (NCT01411995)
- Testing
- 2% lidocaine gel, Water based lubricant
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Intrauterine Contraceptive Device Complication
Uterine Artery Doppler and Menstrual Changes After Insertion Intrauterine Contraceptive Device
To evaluate the correlation between uterine artery Doppler indices and subsequent menstrual changes after 3 months of insertion of copper T-380 IUD and LNG-IUS
- Trial name
- NCT05986344
- Testing
- Copper intrauterine contraceptive device, LNG-IUS
- Where
- Egypt
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Contraception
Immediate Post-placental Insertion of the Copper T 380A After Cesarean Delivery Versus 6 Week Post-cesarean Insertion
The purpose of this study is to determine, in a pilot setting, if this study is feasible in terms of recruitment, willingness to be randomized, provision of contraceptive methods, and follow-up.
- Trial name
- NCT01293760
- Testing
- Immediate insertion, 6 weeks interval insertion
- Where
- Uganda
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
IUD, Endometrial Biopsy
2.5% Lidocaine/2.5% Prilocaine Cream for IUD Insertion and Endometrial Biopsy
The aim of this study is to determine if 5g of self-administered topical 2.5% lidocaine/2.5% prilocaine cream, reduces pain during IUD insertion and/or endometrial biopsy.
- Trial name
- NCT07768059
- Testing
- 2.5% lidocaine/2.5% prilocaine topical cream, VersaPro Cream Base for Compounding
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Lidocaine Toxicity
Lidocaine Spray 10% Versus Oral Ibuprofen Tablets in Pain Control During Copper Intrauterine Device Insertion
The intrauterine contraceptive device (IUD) is the most commonly used form of reversible contraception worldwide; the predominant type of product, the copper IUD (a plastic T-shaped device with copper affixed to it) was developed…
- Trial name
- NCT05241496
- Testing
- The spray form may provide easy application and better patient acceptance than other forms of lidocaine administration
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Marina Ramsis Aziz Ghaly
Contraception
A Study to Compare 3 Doses of a Hormonal Intra-uterine Device Containing Levonorgestrel and Indomethacin With a Hormonal Intra-uterine Device Containing Only Levonorgestrel to Assess the Effect and Safety of the Combined Components
This study is the first study investigating the combined intrauterine administration of LNG (levonorgestrel) and IND (indomethacin). It is a combined proof-of-concept (PoC) and dose finding (DF) study in pre-menopausal women.
- Trial name
- INDessa (NCT03562624)
- Testing
- BAY98-7443, Levonogestrel (Skyla, BAY86-5028)
- Where
- 7 sites in Germany, United Kingdom
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Bayer
Bleeding, Cramping
Quick Start Insertion of Mirena and ParaGard
Intrauterine devices (IUDs) are an effective form of contraception, but only about 3.4% of women in the US report using them. Women must often wait for their menses to start, or for results of screening for sexually transmitted…
- Conditions
- Bleeding, Cramping, Pregnancy With IUD in Place, IUD Expulsion
- Trial name
- NCT01730911
- Testing
- Text message
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Columbia University
Intrauterine Systems, Postpartum Immediate Contraception
Postpartum Immediate Contraception in Cesarean Deliveries-Comparison of Two Intrauterine Systems
To compare two intrauterine systems in order to avoid complications originating from short pregnancy interval and undesired pregnancies in the early postpartum period.
- Trial name
- NCT02941198
- Testing
- GyneFix, Cu T380 A
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
IUD Insertion Complication
Pain Relief During IUD Insertion in Women Delivered Only by Elective Cesarean Section
The aim of the work is to assess the effect of combined misoprostol 200 mcg and isosorbide mononitrate 40 mg versus misoprostol 200 mcg and placebo as local vaginal tablet on the successful IUD insertion.
- Trial name
- NCT03587077
- Testing
- Misoprostol, isosorbide mononitrate
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Assiut University
Genital Tract Mucosal Immunity, Genital Tract Microflora
Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception
This pilot study is being performed to investigate the influence that starting contraception with an IUD has on the local immune cell populations and features, with a particular focus on the cells and cell-surface features that…
- Trial name
- CHIC (NCT01240811)
- Testing
- IUD placement, Levonorgestrel IUD, Copper T380A IUD
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sharon Achilles
Contraception
Impact and Performance of Institutionalizing Immediate Post-partum IUD Services
Studying the impact and performance of institutionalizing immediate post-partum IUD services as a routine part of antenatal counselling and delivery room services in Sri Lanka, Tanzania, and Nepal.
- Trial name
- NCT02718222
- Testing
- Post-partum IUD
- Where
- 3 sites in Nepal, Sri Lanka and 1 more
- Volunteers
- 140,258 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Pain, Anxiety
Effect of Virtual Reality Glasses on Pain and Anxiety During Intrauterine Device Insertion in Women
This study aims to evaluate the effect of virtual reality glasses on pain perception and anxiety levels during intrauterine device insertion in women.
- Trial name
- NCT07325695
- Testing
- Virtual Reality Headset
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Serap Ozturk Altinayak
Endometriosis, Pelvic Pain
The Effectiveness of Lng IUD for Treatment of the Patient Undergone Conservative Surgery for Pelvic Endometriosis
this study is to determine whether the frequency and severity of pelvic pain or dysmenorrhea are reduced in women with symptomatic endometriosis in whom a Lng IUD is inserted after operative laparoscopy compare with those treated…
- Conditions
- Endometriosis, Pelvic Pain, Dysmenorrhea
- Trial name
- NCT00455845
- Testing
- Levonorgestrel IUD
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pain Due to Intrauterine Contraceptive Device
Pain Control for Intrauterine Device Placement Using Paracervical Block
Intrauterine device (IUD) placement can be painful for patients during and after the procedure. Fear of pain from IUD insertion can be a barrier to obtaining this highly effective long acting reversible contraception.
- Trial name
- NCT02219308
- Testing
- Paracervical Block (PCB)
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego