Clinical trials: Intrauterine Device (IUD)
Lidocaine Toxicity
Lidocaine Spray 10% Versus Oral Ibuprofen Tablets in Pain Control During Copper Intrauterine Device Insertion
The intrauterine contraceptive device (IUD) is the most commonly used form of reversible contraception worldwide; the predominant type of product, the copper IUD (a plastic T-shaped device with copper affixed to it) was developed…
- Trial name
- NCT05241496
- Testing
- The spray form may provide easy application and better patient acceptance than other forms of lidocaine administration
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Marina Ramsis Aziz Ghaly
Pelvic Pain, IUD
Multi-dose Ibuprofen Prophylaxis for IUD-insertion
This study compares the effectiveness of decreasing pain at time of and day after intrauterine device (IUD) insertion when patients take three doses of Ibuprofen versus three doses of placebo.
- Trial name
- MIPI (NCT03868137)
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Orlando VA Medical Center
Contraceptive Device; Intrauterine
Discontinuation Rate Among Copper IUD Users
The intrauterine device (IUD) is one of the most widely used reversible, long-term contraceptive methods in the world. But despite all its advantages; discontinuation rate of IUD ranged from 9.6% to 37.3 % (according to…
- Trial name
- NCT03404102
- Testing
- Cu-IUD
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- noha mohamed elzaydy
Menorrhagia
Treatment of Copper Intra Uterine Device Associated Heavy Menstrual Blood Loss
Intrauterine contraceptive device is the most commonly reversible method used among women of reproductive age worldwide. Almost one in five married contraceptive users is currently using Intrauterine contraceptive device.
- Trial name
- NCT03139422
- Testing
- Tranexamic Acid 500 MG, Calcium Dobesilate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University
Contraception, Pain
Efficacy of Intrauterine Lidocaine and Naproxen for Pain Control With Intrauterine Device Insertion
To compare the efficacy of intrauterine lidocaine and oral naproxen sodium on discomfort and pain of patients undergoing intrauterine device insertion.
- Trial name
- NCT02769247
- Testing
- Naproxen, Lidocaine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Intrauterine Contraceptive Device Complication
Uterine Artery Doppler and Menstrual Changes After Insertion Intrauterine Contraceptive Device
To evaluate the correlation between uterine artery Doppler indices and subsequent menstrual changes after 3 months of insertion of copper T-380 IUD and LNG-IUS
- Trial name
- NCT05986344
- Testing
- Copper intrauterine contraceptive device, LNG-IUS
- Where
- Egypt
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Pain Prior to IUD Insertion
Misoprostol Prior to Intrauterine Contraceptive Device Insertion
Intrauterine devices (IUDs) are widely used as reversible contraceptives. Both copper- and levonorgestrel (LNG)-releasing IUDs (LNG-IUDs) are safe,cost-effective in the long term and equally effective compared with tubal…
- Trial name
- NCT02412033
- Testing
- Misoprostol
- Volunteers
- 140 people
- Sponsor
- Assiut University
Contraception
RAPID EC - Rct Assessing Pregnancy With Intrauterine Devices for EC
This study is a randomized trial of two IUDs for emergency contraception: the copper IUD, the most effective method of emergency contraception vs.
- Trial name
- NCT02175030
- Testing
- Copper IUD, Levonorgestrel IUD
- Where
- 6 sites in United States
- Volunteers
- 711 people
- Sponsor
- University of Utah
Unplanned Pregnancy
A Pilot Study of Early Postpartum Intrauterine Contraception
This is a prospective clinical trial of ultrasound guided intrauterine contraception insertion 10 minutes - 48 hours after vaginal delivery of single infant.
- Trial name
- ImmPPIUD (NCT00997932)
- Testing
- Levonorgestrel-Releasing Intrauterine Contraceptive System (LNG-IUS), 52 Mg, 5 Year Duration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
IUD Insertion Complication
Different Analgesics Prior to Intrauterine Device (IUD) Insertion: Is There Any Evidence?
Different ways of reducing pain during IUD insertion have been explored. So a randomized study will be conducted to test their role
- Trial name
- NCT02522130
- Testing
- Lidocaine, oral misoprostol, naproxen
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al Hayat National Hospital
Contraception, Postpartum
Monitoring With Ultrasound Imaging of Intrauterine Device (IUD) Position Placed Immediately After Giving Birth
Intrauterine devices (IUDs) are one of the most effective reversible forms of contraception, and are a good option in the postpartum period for women to avoid a rapid repeat pregnancy.
- Trial name
- NCT02024672
- Testing
- Immediate postpartum placement of IUD
- Where
- 2 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Intrauterine Device
The Effect of Virtual Reality on Anxiety During Intrauterine Device Insertion
This study was planned to determine whether the use of virtual reality glasses during intrauterine device insertion has an effect on the anxiety level of women.
- Trial name
- NCT06179095
- Testing
- Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
IUD Insertion
Vaginal Dinoprostone Administration Prior to an Intrauterine Device Insertion in Multiparous Women.
To investigate whether vaginal dinoprostone administered before intrauterine device (IUD) insertion reduces failed insertions, insertion-related complications, and pain in multiparous women.
- Trial name
- NCT04046302
- Testing
- Dinoprostone
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Uterine Hemorrhage
Management of Initial Bleeding/Spotting Associated With the Levonorgestrel-releasing Intrauterine System (MIRENA)
The purpose of the study is to investigate if the study drugs (tranexamic acid or mefenamic acid) can control irregular bleeding during the first 3 months of using Mirena.
- Trial name
- NCT01295294
- Testing
- Tranexamic acid, Mefenamic acid, Mirena (Levonorgestrel IUS, BAY86-5028)
- Where
- 12 sites in Denmark, Ireland and 1 more
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Bayer
Idiopathic Menorrhagia
Mirena in Idiopathic Menorrhagia
This is an open-label, uncontrolled, multi-centre observational study that analyses a follow-up of 1600 women with dysfunctional uterine bleeding (idiopathic menorrhagia) over a period of one year.The patients evaluated at four…
- Trial name
- NCT00868153
- Testing
- Levonorgestrel IUS (Mirena , BAY86-5028)
- Where
- 13 sites in Bulgaria, Croatia and 11 more
- Volunteers
- 1,125 people
- Sponsor
- Bayer
Blood Coagulation Disorders
The Effect of a Levonorgestrel-releasing Intrauterine Device (IUD) Versus a Copper Containing IUD on Risk of Blood Clots
This is a randomized controlled trial to assess the effect of a levonorgesterel-releasing intrauterine device (LNG IUD, Mirena®) versus a copper IUD (Paraguard®) on coagulation parameters known to be associated with risk of…
- Trial name
- NCT00584610
- Testing
- Levonorgestrel-containing IUD (Mirena®), Copper-containing IUD (Paraguard®)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Contraception
Topical Lidocaine on the Cervix and Intra-Cervical Prior to Insertion of Intrauterine Devices
The hypothesis of this study is that topical cervical and intra-cervical lidocaine will decrease pain associated with the insertion of a Mirena® (levonorgestrel intrauterine device). 1.
- Trial name
- 10-053 (NCT01192490)
- Testing
- Lidocaine, Lubricant
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Contraception
Use of Misoprostol for Intrauterine Device (IUD) Insertion in Nulliparous Women
The purpose of this study is to evaluate if the use of misoprostol can make it easier for a provider, and less painful for a woman, to place an IUD if she has never had a child before.
- Trial name
- NCT01001897
- Testing
- Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Intrauterine Device (IUD), Abnormal Uterine Bleeding
Suction Cervical Stabilizer Compared to Standard Tenaculum for Intrauterine Procedures
To evaluate patient-reported pain, bleeding, and device efficiency along with provider satisfaction and ease of use between intrauterine procedures employing a suction cervical stabilizer (new device, FDA approved, atraumatic) or…
- Trial name
- NCT06193590
- Testing
- Carevix, Tenaculum
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Indiana University
IUD Insertion Complication, Acute Pain
LI4 Acupuncture for Analgesia in Intrauterine Device Insertion
Pain during IUD insertion is substantially psychologic in origin, responds extremely well to non-pharmacologic interventions. Considering the fact that acupuncture is a modality exerting both psychologic and physiologic effects…
- Trial name
- NCT04963582
- Testing
- Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University