Clinical trials: Intrauterine Fetal Growth Restriction
Intrauterine Growth Restriction, Small-for-gestational Age
Ultrasound Evaluation of Fetal Hemodynamics and Perinatal Complications
In case of fetal weight below the 10th centile for gestational age, it is important to distinguish SGA and IUGR. SGA is defined as a fetal weight below the 10th centile.
- Trial name
- PTI'DOP (NCT03865628)
- Volunteers
- 1,200 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Intrauterine Growth Restriction
Evaluation of Infants With Intrauterine Growth Restriction
Purpose: Clinical assessment (anthropometric) and paraclinical (biochemical and immunological by dosing serum insuline growth factors IGF1 and IGF2 and their receptors) of neonates with intrauterine growth restriction (IUGR) and…
- Trial name
- ModeInfIUGR (NCT02515292)
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Intrauterine Growth Restriction
The Effect of Antenatal Corticosteroid on Umbilical Artery Doppler Velocimetry in IUGR
The purpose of this study is to evaluate the effect of antenatal corticosteroid administration on umbilical artery Doppler velocimetry measurements in pregnancies complicated by IUGR.
- Trial name
- NCT05588986
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people
- Sponsor
- Merve Demir
Intrauterine Growth Restriction
Intraumbilical Amino Acids and Glucose Supplementation Via Port by Severe IUGR in Human Fetuses
Placental insufficiency is responsible for fetal loss in about 40% of all stillbirths and long term neurological deficits. The mean interval from diagnosis of brain sparing of severe IUGR fetuses to delivery has been recently…
- Trial name
- port-IUGR (NCT02596594)
- Testing
- fetal nutrition port system
- Volunteers
- 14 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Fetal Growth Restriction, Placenta
Placental Progesterone Membrane Receptors in Fetal Growth Restriction
This prospective observational case-control study aims to compare placental expression levels of progesterone membrane receptors, including PGRMC1, PGRMC2, and PAQR family receptors, among pregnancies affected by impaired fetal…
- Conditions
- Fetal Growth Restriction, Placenta, Progesterone Membrane Receptor, PGRMC1
- Trial name
- NCT07701837
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Samsun University
Growth Hormone Deficiency, Small-for-gestational Age
Growth and Asymmetric diMethylArginine
Principal objective : Validation of a handy biochemical parameter, plasma concentration of Asymmetric DimethylArginine (ADMA), based on a recognize biochemical parameter, the dilation of the brachial artery, at ultrasound…
- Trial name
- GAMMA (NCT03422081)
- Testing
- arterial doppler ultrasound
- Where
- 2 sites in France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Lille
Fetal Conditions
The Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamic and Neonatal Outcome
This study will be conducted to show the effect of different degrees of maternal iron deficiency anemia on fetal hemodynamics and neonatal outcome and to evaluate the effect of treatment.
- Trial name
- NCT04016922
- Testing
- Oral ferrous fumerate for Group A, Parenteral iron sucrose for Group B, Compatible blood transfusion for Group C
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Growth Disorders, Intrauterine Growth Retardation
Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation
To evaluate the effect of continuous and intermittent administration of Genotonorm on stature in short prepubertal children with intra-uterine growth retardation
- Trial name
- NCT01073605
- Testing
- Genotonorm
- Where
- 31 sites in France
- Volunteers
- 208 people
- Sponsor
- Pfizer
Pregnancy, Primiparity
MorbiMortality Amelioration in Preeclamptic Primiparas Study. MoMA Pre Prim Study
The purpose of this study is to determine whether close monitoring of patients with a high sFlt1 plasma level between 25 and 28 weeks of gestation (i.e.
- Conditions
- Pregnancy, Primiparity, Hypertension, Preeclampsia
- Trial name
- MOMA (NCT00763672)
- Testing
- Transmission of sFlt-1 results to the investigator, No transmission of the sFlt-1 results to the investigator
- Where
- France
- Volunteers
- 1,040 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intrauterine Growth Restriction
Prediction of Low Birth Weight Infants Using Ultrasound Measurement of Placental Diameter and Thickness
Prediction of Low Birth Weight Infants using Ultrasound Measurement of Placental Diameter and Thickness
- Trial name
- NCT01501851
- Where
- Egypt
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Intrauterine Growth Restriction, Premature - Weight 1000g-2499g or Gestation of 28-37weeks
Influence of Intrauterine Growth Restriction on Amplitude-integrated EEG in Preterm Infants
Objective: The impact of intrauterine growth restriction (IUGR) on perinatal morbidity and long-term neurodevelopmental outcome has been published in numerous studies.
- Conditions
- Intrauterine Growth Restriction, Premature - Weight 1000g-2499g or Gestation of 28-37weeks, Neurodevelopmental Disorder, EEG; Spikes, Centrotemporal, Epilepsy of Childhood
- Trial name
- NCT01942525
- Testing
- aEEG
- Where
- Austria
- Volunteers
- 156 people
- Sponsor
- Medical University of Vienna
Foetal Growth Problem, Small for Gestational Age
Long Term Effect of Somatropin in Subjects With Intrauterine Growth Retardation
This trial is conducted in Europe. The aim of this trial is to assess the safety of long-term growth hormone treatment in growth-retarded children with intrauterine growth retardation (IUGR) enrolled in trial GHRETARD/F/1/F.
- Trial name
- NCT01734447
- Testing
- somatropin
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Novo Nordisk A/S
Fetal Growth Retardation
Melatonin to Prevent Brain Injury in Unborn Growth Restricted Babies
Intrauterine growth restriction is the term used to describe a condition where an unborn baby does not reach its optimum size. In the short and long term, intrauterine growth restricted babies have a higher risk of serious…
- Trial name
- NCT01695070
- Testing
- Melatonin
- Where
- Australia
- Volunteers
- 16 people
- Sponsor
- Monash University
Fetal Growth Restriction
COmputerized CTG Self-MOnitoring Versus Standard Doppler Assessment in Late-onset FGR: COSMOS Study
Fetal growth restriction is one of the major causes of perinatal morbidity, mortality and adverse neurological outcome. Growth restricted fetuses do not reach their potential due to multiple factors.
- Trial name
- COSMOS (NCT05034861)
- Testing
- cCTG, Doppler
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Institute of Mother and Child, Warsaw, Poland
Chronic Histiocytic Intervillositis, Intrauterine Growth Retardation
Exploration of Allograft Humoral Rejection in Chronic Histiocytic Intervillositis
Chronic histiocytic intervillositis (CHI) is a rare condition with an incidence of 5 in 10,000 pregnancies. This rare condition is associated with placental inflammatory lesions leading to severe and recurrent obstetrical…
- Conditions
- Chronic Histiocytic Intervillositis, Intrauterine Growth Retardation, Fetal Death in Utero, Miscarriage
- Trial name
- RH-PL (NCT05936333)
- Testing
- Biological collection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intrauterine Growth Retardation, Feeding Patterns
The Effect of Neonatal Feeding Modalities on Splanchnic Oxygenation
OBJECTIVES: The main purpose of this study was to evaluate the impact of drip versus intermittent feeding on splanchnic oxygenation in preterm infants with intrauterine growth restriction (IUGR).
- Conditions
- Intrauterine Growth Retardation, Feeding Patterns, Splanchnic Hypoperfusion
- Trial name
- NCT05513495
- Testing
- The effect of drip versus intermittent feeding on splanchnic oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ozge Surmeli Onay
Stillbirth, Fetal Death
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
Fetal growth restriction during pregnancy represents one of the biggest risk factors for stillbirth (Gardosi et al, 2013), with 'about one in three term, normally formed antepartum stillbirths are related to abnormalities of…
- Conditions
- Stillbirth, Fetal Death, Fetal Growth Retardation, Small for Gestational Age
- Trial name
- OxGRIP (NCT03662178)
- Where
- United Kingdom
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Pre-Eclampsia
First Trimester Screening for Preeclampsia and Intrauterine Growth RestrIction Using Three Dimensional Doppler Angiography
Introduction: Preeclampsia (PE) and intrauterine growth restriction (IUGR) are two major pregnancy complications, related to a chronic utero-placental hypoperfusion.
- Trial name
- SPIRIT (NCT03342014)
- Testing
- Ultrasound, Blood sample collection
- Where
- France
- Volunteers
- 2,159 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Intrauterine Growth Restriction, Fetal Growth Retardation
Improving Mothers for a Better PrenAtal Care Trial Barcelona
High risk women for growth restricted fetuses will randomized in the second trimester into different strategies applied to the mothers: a stress reduction program based on mindfulness techniques or a nutrition interventional…
- Trial name
- IMPACTBCN (NCT03166332)
- Testing
- Mediterranean diet, Mindfulness
- Where
- 2 sites in Spain
- Volunteers
- 1,221 people
- Sponsor
- Hospital Clinic of Barcelona
Healthy Volunteers
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors…
- Trial name
- NCT04286464
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern