Clinical trials: Intravascular Ultrasound
Thoracic Aortic Aneurysm
Intravascular Ultrasound (IVUS) in Complex Aortic Endovascular Interventions
The study aims to investigate the applicability of intravascular ultrasound (IVUS) in the endovascular therapy of juxta-, supra- and thoracoabdominal aortic aneurysms.
- Trial name
- NCT04663074
- Testing
- IVUS control
- Where
- 6 sites in Denmark, Germany and 2 more
- Volunteers
- 80 people
- Sponsor
- University Hospital Muenster
Coronary Artery Disease, Coronary Stenosis
Multimodality Optical and Ultrasound Intravascular Imaging for Stent Optimization and Atheroma Assessment
This investigation is to see if the new Novasight Hybrid imaging catheter can safely and accurately provide two different types of images (IVUS and OCT) of the inside of heart vessels at the same time.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Plaque, Atherosclerotic
- Trial name
- MOUSA (NCT05753085)
- Testing
- Conavi Medical Novasight Hybrid System intervention
- Where
- United Kingdom
- Sponsor
- Barts & The London NHS Trust
Coronary Disease
VH-IVUS Plaque Composition Analysis By Fractional Flow Reserve
Recent clinical trials demonstrated that virtual histology-intravascular ultrasound (VH-IVUS) is a useful test predicting clinical outcomes of the coronary artery disease (CAD).
- Trial name
- NCT01444599
- Where
- 4 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Inje University
Left Main Coronary Artery Disease
Functional Diagnostic Accuracy of Ultrasonic Flow Ratio in Assessment of Left Main Coronary Artery Stenosis
This is a prospective, observational, single-center study. The main purpose of this study is to evaluate the diagnostic accuracy of offline computational ultrasonic flow ratio (UFR) in predicting functionally significant left…
- Trial name
- FUNCTION II (NCT06053944)
- Testing
- fractional flow reserve (FFR); ultrasonic flow ratio (UFR); intravascular ultrasound (IVUS)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
The Implementation of Intravascular Ultrasound and Fractional Flow Reserve in the Percutaneous Treatment of Very Long Coronary Artery Lesions
A single center, prospective, observational study to investigate the impact of intravascular ultrasound (IVUS) on the functional percutaneous coronary intervention (PCI) result (assessed with fractional flow reserve (FFR)) and…
- Trial name
- NCT05621421
- Testing
- FFR and IVUS guided PCI
- Where
- Lithuania
- Volunteers
- 80 people
- Sponsor
- Vilnius University Hospital Santaros Klinikos
Hepatocellular Carcinoma
Intravascular Ultrasound for Hepatocellular Carcinoma Staging
To diagnose hepatocellular carcinoma (HCC) and to determine the extent of the disease, a triphasic CT scan or a magnetic resonance imaging are required.
- Trial name
- NCT00474734
- Testing
- Intravascular ultrasound of the liver
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Heart Transplantation, Coronary Artery Disease
Comparison of CT Angiography With Conventional Angiography and Intravascular Ultrasound in Heart Transplant Patients
The overall goal of this study is to determine if non-invasive imaging with state of the art CT coronary angiography can be used to screen for transplant coronary artery disease in the setting of heart transplant.
- Trial name
- NCT00723281
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, San Francisco
Peripheral Artery Disease
Directional Versus Orbital Atherectomy Plaque Modification and Luminal Area Assessment of the Femoro-popliteal Artery Via Intravascular Ultrasound
This single center prospective, randomized study will be conducted to investigate plaque removal and luminal gain using CSI's DIAMONDBACK 360® Peripheral Orbital Atherectomy System (OAS) (St.Paul, MN) versus Medtronic's Hawkone…
- Trial name
- NCT03495453
- Testing
- Percutaneous Revascularization of the Femoropopliteal Arteries using a DAS, Percutaneous Revascularization of the Femoropopliteal Arteries using a OAS device
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- NYU Langone Health
Coronary Artery Disease (CAD)
Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging
Both intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are standardly used and have been extensively studied separately to guide percutaneous coronary intervention and improve long-term outcomes.
- Trial name
- NCT02984891
- Testing
- Optical Coherence Tomography (OCT), Intravascular Ultrasound (IVUS)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Columbia University
Coronary Occlusion
Comparative Study Between Intravascular Ultrasonography Guided and Angiography-guided Recanalization of Coronary Chronic Total Occlusions
Chronic total occlusion is defined as thrombolysis in myocardial infarction (TIMI) flow grade 0 with an estimated duration of at least 3 months.
- Trial name
- NCT03159650
- Testing
- intravascular ultrasonography
- Volunteers
- 80 people
- Sponsor
- Assiut University
Coronary Arteriosclerosis
A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)
The purpose of this study is to see if 40 mg of rosuvastatin taken daily will reduce the atherosclerosis (fatty deposits) in your arteries
- Trial name
- NCT00240318
- Testing
- Rosuvastatin calcium
- Where
- 61 sites in United States, Australia and 6 more
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Coronary Artery Disease
Intravascular Ultrasound Versus Angiography Guided Drug-coated Balloon
Drug-coated balloon (DCB) is an alternative choice for denovo lesions in coronary artery disease patients with high bleeding risk.
- Trial name
- ULTIMATE-III (NCT04255043)
- Testing
- IVUS guidance, Angiography guidance
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coronary Artery Disease
FFR Versus IVUS With Angiography-Derived FFR for Clinical Outcomes in Patients With Coronary Artery Disease
To compare the clinical outcomes of fractional flow reserve (FFR)-guided strategy versus intravascular ultrasound (IVUS)-guided stent implantation after angiography-derived FFR-based decision-making.
- Trial name
- FLAVOUR III (NCT06218485)
- Testing
- Intravascular ultrasound-guided stent implantation after angiography-derived FFR-based decision-making, Fractional flow reserve-guided PCI strategy
- Where
- 32 sites in China, South Korea
- Volunteers
- 1,942 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease
Clinical Impact of Intravascular Ultrasound-Based Artificial Intelligence Technologies (INNOVATE-PCI)
This study is a prospective, multicenter study in the real practice to validate the diagnostic performances and clinical impact of coronary angiography \& intravascular ultrasound (IVUS)-based models developed by machine learning…
- Trial name
- NCT05807841
- Testing
- percutaneous coronary intervention
- Where
- 16 sites in South Korea
- Volunteers
- 3,000 people
- Sponsor
- Asan Medical Center
Coronary Artery Stenosis
Functional Diagnostic Accuracy of Ultrasonic Flow Ratio in Assessment of Coronary Artery Lesions
This is a prospective, single-center study. The primary purpose of this study is to evaluate the sensitivity and specificity of offline computational ultrasonic flow ratio (UFR) with conventional pressure wire-based fractional…
- Trial name
- FUNCTION (NCT06052670)
- Testing
- fractional flow reserve (FFR); ultrasonic flow ratio (UFR); intravascular ultrasound (IVUS)
- Volunteers
- 408 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cardiac Arrest
Intravascular Clotting (POCUS) - Marker of the Timing and Severity of Cardiac Arrest; Indicator of Futile Resuscitation
The scientific goals of the project: 1. ultrasound assessment of the incidence of clotting in deep veins in patients after cardiac arrest during resuscitation and after the declaration of death; comparison to the incidence of…
- Trial name
- NCT06406920
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Peripheral Artery Disease, Critical Limb Ischemia
Complete Lesion Assessment With ffR and IVUS TechnologY
CLARITY I is a pilot study to identify the clinically appropriate endpoint(s) of a larger, statistically powered pivotal trial for treatment of patients with Critical Limb Ischemia (CLI).
- Trial name
- CLARITY I (NCT01941030)
- Testing
- Orbital Atherectomy System, Balloon Angioplasty
- Where
- 8 sites in United States
- Volunteers
- 51 people
- Sponsor
- Abbott Medical Devices
Coronary Disease
Optimal Physiologic Intravascular Ultrasound Imaging Criteria After Drug Eluting Stent Implantation
Invasive imaging criteria of the Coronary arteriography (CAG) and intravascular ultrasound imaging (IVUS), satisfying procedural optimization after drug eluting stent (DES) implantation, were used in < 10% DS by CAG and 5-5.5mm2…
- Trial name
- NCT01667757
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Inje University
Coronary Artery Occlusion
IVUS Analysis for Coronary Obstruction in TAVI
Observational, prospective, single-arm and multi-center study to assess the safety and feasibility of IVUS imaging in the setting of TAVI and to describe the angiographic and intravascular ultrasound features in patients with…
- Trial name
- ICARO (NCT05164796)
- Testing
- IVUS assessment of coronary ostia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Universita di Verona
Uncontrolled Essential Hypertension
Ultrasound Ablation for Essential Hypertension（FIM）
To evaluate the safety and feasibility of disposable intravascular ultrasound ablation catheter and ultrasound ablation instrument in the treatment of essential hypertension.
- Trial name
- NCT05795829
- Testing
- disposable intravascular ultrasound ablation catheter and ultrasound ablation instrument
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- Lepu Medical Technology (Beijing) Co., Ltd.