Clinical trials: Intravascular Volume
Hyponatremia, Hyponatremia With Extracellular Fluid Depletion
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status
Hyponatremia is the most frequent electrolyte disorder encountered in clinical practice. The patient approach, however, is still problematic, above all because hyponatremia is a manifestation correlated to various pathological…
- Conditions
- Hyponatremia, Hyponatremia With Extracellular Fluid Depletion, Hyponatremia With Normal Extracellular Fluid Volume, Hyponatremia With Excess Extracellular Fluid Volume
- Trial name
- NCT04402190
- Where
- Italy
- Volunteers
- 123 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Diuresis, Bladder Retention Volume
Effect of Preload on Bladder Retention Volume During Spinal Anesthesia
The purpose of this study is to assess the influence of different fluid infusions on the quantity of bladder retention after spinal anesthesia.
- Conditions
- Diuresis, Bladder Retention Volume, Hypotension
- Trial name
- NCT00550186
- Testing
- Ringers Lactate, HaemoHES 6%
- Where
- Netherlands
- Volunteers
- 144 people
- Sponsor
- Rijnstate Hospital
Hemorrhage
Comparison of Compensatory Reserve Index to Intravascular Volume Change and Stroke Volume
This study is designed to validate implementation of the CRI algorithm in the CypherOx CRI system. Healthy human subjects will undergo progressive reduction in central blood volume to the point of hemodynamic instability (defined…
- Trial name
- NCT01935427
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Chronic Kidney Failure
Intravascular Volume Assessment Using Ultrasonography in Pediatrics Renal Transplant: A Prospective Cohort Study
This study is designed for volume assessment in pediatrics during major surgery using non-invasive tools as ultrasonography without the need of invasive techniques avoiding its complications and as a guide for fluid therapy…
- Trial name
- NCT04008953
- Testing
- ultrasonography
- Volunteers
- 16 people
- Sponsor
- Fatma Alzahraa Mohamed Ibrahim Hassan Haggag
Intravascular Volume, Respiratory Changes
Fluid Management Study to Evaluate Changes in Intravascular Volume After Applying Various Pressure Levels on the Caval Vein
Fluid therapy optimization in the perioperative period has been considered as major contributor to improve oxygen delivery. A recent, noninvasive approach to estimate fluid requirements in the anesthetized patient with arterial…
- Trial name
- NCT01388998
- Testing
- Changes of difference in pulse pressure and plethysmography after applying various pressure levels on the caval vein
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Johannes Gutenberg University Mainz
Hypovolemia, Craniosynostoses
Bedside Resources to Gauge Intravascular Volume Status
The goal if this study is to employ the CardioQ-Esophageal Aortic Doppler probe to define fluid responders from non-responders among infants undergoing cranial vault reconstruction for craniosynostosis.
- Trial name
- NCT03915587
- Testing
- CardioQ-EDM and CipherOx-CRI
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Fasting Period, Intravascular Volume
The Impact of Preoperative Fasting Period on Cardiac Index Variability After Anesthesia Induction in Pediatric Patients
The minimum period of fasting recommended by the 'American Society of Anesthesiologists' for the preoperative period is 6 hours for solid foods and 2 hours for clear liquids.
- Trial name
- NCT03406481
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Marmara University
Coronary Disease, Ultrasonography, Interventional
Virtual Histology Findings and Effects of Varying Doses of Atorvastatin Treatment
While statin treatment may induce plaque regression, the effect of statin on plaque composition with varying doses is unknown. This study assessed such effects by volumetric virtual histology intravascular ultrasound (VH-IVUS).
- Conditions
- Coronary Disease, Ultrasonography, Interventional, Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Trial name
- VENUS (NCT01200056)
- Testing
- Atorvastatin 10mg versus 40mg.
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Prof. Stephen Lee
Brain Swelling, Brain Edema
Furosemide vs Placebo for Brain Relaxation
Increased brain bulk may be problematic during brain surgery for tumors because it may limit surgical exposure and access to the surgical site.
- Conditions
- Brain Swelling, Brain Edema, Dehydration
- Trial name
- NCT01054404
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Northwestern University
Spinal Induced Hypotension, Geriatric Population
Spinal-Induced Hypotension in Geriatric Patients
The study will be conducted to asses preoperative condition of venous system by VExUS score and it's relation with the incidence of spinal induced hypotension in geriatric patients undergoing surgery with spinal anaesthesia.
- Conditions
- Spinal Induced Hypotension, Geriatric Population, Intravascular Volume
- Trial name
- NCT05862298
- Testing
- venous excess ultrasound score
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Hemorrhage
Comparison of Physiological Variables During Blood Donation
The investigators have developed a system based on a pulse oximeter, a tablet, and an algorithm running on the tablet that analyzes the pulse oximeter waveform.
- Trial name
- NCT02029807
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Type2 Diabetes Mellitus, Cardiovascular Diseases
Effects of Canagliflozin on Intravascular Volume and Hemodynamics
RESEARCH HYPOTHESIS In subjects with T2DM and HF, effect of canagliflozin will be superior to placebo for the change from baseline in PCWP after a single dose (6 hours post-dose) and after 4 weeks.
- Trial name
- NCT03190798
- Testing
- Canagliflozin 300mg
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Unintubated Patients in ICU and Resuscitation Room
Measurement of Intravascular Volume Using USG of IVC Diameter Compared to VPW Chest X-ray
This study aimed to know the consistency of intravascular volume measurement using USG of IVC compared to VPW chest x-ray
- Trial name
- NCT03535038
- Testing
- Inferior vena cava (IVC) diameter using USG, Vascular pedicle width (VPW)
- Where
- Indonesia
- Volunteers
- 35 people
- Sponsor
- Universitas Indonesia
Comparison Between Perfusion Index and Pulse Pressure Variability for Prediction of Intravascular Volume During Major Abdominal Surgeries
Comparison Between Perfusion Index and Pulse Pressure Variability for Prediction of Intravascular Volume During Major Abdominal Surgeries
Each year, at least 310 million patients undergo major surgery worldwide, procedures that involve the administration of intravenous fluids Intraoperative hemodynamic management is challenging because precise assessment of the…
- Trial name
- NCT07024108
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Hypoxia, Confinement
Intravascular Volumes in Hypoxia During Antarctic Confinement
This study evaluates the effect of hypoxia on blood volumes during Antarctic winter-over confinement. Half of the participants will be evaluated during sea-level winter-over confinement, while the other half will be examined…
- Trial name
- ANTARCV (NCT04106401)
- Testing
- carbon-monoxide rebreathing, venous blood sampling, physical activity monitoring
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ecole Nationale des Sports de Montagne
Liver Cirrhosis
EJV Occlusion Pressure Measurement to Assess Intravascular Volume in Cirrhotic Patients During IV Albumin Substitution
Cirrhotic patients with an indication for intravenous albumin will undergo a venous compression technique of the external jugular vein plus an ultrasound examination before/after passive leg raise as well as before/after…
- Trial name
- CPMX2 (NCT06544161)
- Testing
- CPMX2
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sepsis
A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status
Patients may have actual or relative intravascular volume depletion in a number of different disease states, particularly with sepsis syndrome.
- Trial name
- NCT00599794
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy Volunteers
Dynamics of Stroke Volume and Cardiac Output During Parabolic Flight, and Its Relationship to Intravascular Volume
To understand the cardiovascular reactions of the human body to changing conditions of gravity is an important aim of space science. In this context, cardiac output (CO) is a key value to estimate the human cardiovascular system.
- Trial name
- DYMCO (NCT02518880)
- Testing
- Parabolic flight, plasma volume measurements
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Cardiovascular Surgical Procedures, Albumin
Albumin Utilization in Adult Cardiac Surgical Patients: Retrospective
All heart surgery patients universally require hydration, which is given through a vein in the arm, but practices for treating patients are not universal.
- Trial name
- AlbACS-1R (NCT06322537)
- Where
- 10 sites in Canada
- Volunteers
- 505 people
- Sponsor
- University Health Network, Toronto
Assessment of Intravascular Volume Status in Mechanically Ventilated Critically Ill Patients
Evaluation of Jugular Venous Distensibility Index in Intravascular Fluid Management and Comparison of the Effectiveness of Noninvasive and Minimally Invasive Methods
Assessment of intravascular volume status is an important component of hemodynamic management in critically ill patients. Several noninvasive and minimally invasive parameters, including the pleth variability index (PVI), pulse…
- Trial name
- NCT07807709
- Testing
- Pleth variability index, Pulse pressure variation, Stroke volume variation
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital