Clinical trials: Intravenous
Postoperative Nausea and Vomiting
Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic.
- Trial name
- NCT01734161
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
General Anesthesia, Intravenous Anesthesia
Combination of Magnesium and Lidocaine for the Pretreatment of Pain That is Caused by the Injection of Propofol
Since the introduction of propofol into routine anesthesia practice, the phenomena of pain on injection has plagued anesthesia providers. Propofol, an unstable phenol, triggers the release of bradykinin on injection.
- Trial name
- NCT01342510
- Testing
- Magnesium Sulfate, Lidocaine, Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Colonoscopy, Bowel Preparation
Acid-base Balance in Patients Undergoing Colonoscopy
The purpose of this study is to determine whether fluid administration in patients undergoing colonoscopy should affect acid-base disorder in term of the strong ion differences.
- Trial name
- NCT01250886
- Testing
- Lactated Ringer's solution, Normal saline solution, Acetate Ringer's solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy Volunteers
Study to Evaluate the Safety/Tolerability, PK and PD After Intravenous DWJ1521 Administration in Healthy Volunteers
A randomized, double-blind, placebo-controlled, multiple-dose clinical trial to evaluate the safety/tolerability and pharmacokinetics, and pharmacodynamics after intravenous DWP14012 injection in healthy volunteers
- Trial name
- NCT06508645
- Testing
- DWP14012 injection
- Where
- South Korea
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy Volunteers
A Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of E2025 in Healthy Participants
The primary purpose of the study is to evaluate the safety and tolerability of single intravenous (IV) infusions of E2025 in healthy adult participants.
- Trial name
- NCT05726851
- Testing
- E2025
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Iron Deficiency Anemia of Pregnancy
Chelated Oral Iron Versus Intravenous Iron Sucrose for Treatment of Iron Deficiency Anemia Late in Pregnancy
compare the efficacy and safety of intravenous iron sucrose versus chelated oral iron in the treatment of iron deficiency anemia late in pregnancy.
- Trial name
- NCT05151679
- Testing
- Chelated Iron, Iron sucrose
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assiut University
Sedation
Intravenous Infusion of Lidocaine in Gastroscopy
Intravenous infusion of lidocaine significantly reduces incidence of bucking when perfomed gastroscopy.
- Trial name
- NCT04439773
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shandong University
Arthritis, Rheumatoid, Inflammation
A Study To Look At The Safety Of SB-681323 In Healthy Adult Subjects After Intravenous Administration Of A Single Dose
SB-681323 inhibits the action of an enzyme which is known to contribute to the inflammation seen in such conditions as Chronic Obstructive Pulmonary Disease and Rheumatoid Arthritis.
- Trial name
- NCT00439881
- Testing
- SB-681323
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV/AIDS
Study to Evaluate Pharmacokinetic and Safety of Albuvirtide Between Intravenous Drip and Intravenous Injection
This is a single-center,randomized,open, single-dose, parallel-design study, which will be only enrolled Chinese healthy volunteers.
- Trial name
- NCT05206019
- Testing
- Albuvirtide
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
Prevention
Intravenous Versus Intraperitoneal Instillation of Ondansetron for Decreasing Incidence of Nausea and Vomiting After Laparoscopic Gynecological Surgeries.
Study the effect of intraperitoneal instillation vs intravenous ondansetron on PONV added to intraperitoneal bupivacaine for enhanced recovery and to decrease incidence of PONV after laparoscopic surgeries.
- Trial name
- NCT05317611
- Testing
- Intraperitoneal instillation of ondansetron and bupivacaine, Intravenous ondansetron and intraperitoneal instillation of bupivacaine, Intraperitoneal instillation of bupivacaine
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pain, Renal Colic
Comparison of IV 10, 20, and 30mg for Renal Colic Pain in the ED
Hypothesis: Intravenous administration of Ketorolac 10 mg and 20 mg is as effective as 30 mg in treating renal colic pain in patients presenting to the emergency department
- Trial name
- NCT03665753
- Testing
- Ketorolac
- Where
- Iran
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Alzheimer's Disease, Healthy Participants
A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration
The purpose of this study is to evaluate the drug levels, absolute bioavailability, safety, tolerability, and immunogenicity of single-Dose of BMS-986446 in healthy adults after single-dose administration, and participants with…
- Trial name
- NCT07780383
- Testing
- BMS-986446
- Where
- 6 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy Participants, Primary Sjögren's Syndrome
BMS-986325 in Healthy Participants and Participants With Primary Sjögren's Syndrome
The purpose of this study is to evaluate the safety, tolerability, drug levels, and drug effects of BMS-986325 in healthy participants and participants with primary Sjögren's syndrome.
- Trial name
- NCT04684654
- Testing
- BMS-986325
- Where
- 2 sites in United States, Germany
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Alzheimer's Disease
Absolute Bioavailability of a Single, Fixed Subcutaneous Dose of Aducanumab in Healthy Participants
The primary objectives of this study are to evaluate the absolute bioavailability of a single, fixed sub-cutaneous (SC) dose of aducanumab compared with a single, weight-based intra-venous (IV) dose in healthy participants and to…
- Trial name
- NCT02782975
- Testing
- aducanumab
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biogen
Healthy
Safety, Tolerability and Pharmacokinetics of Single Rising Intravenous Doses of BI 44370 BS Solution in Healthy Male Volunteers
Study to investigate safety, tolerability, and pharmacokinetics of BI 44370 BS solution for intravenous (i.v.) infusion
- Trial name
- NCT02215031
- Testing
- BI 44370
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Haemophilia A
A Study Looking at How Different Doses of Study Medicine (Inno8) Works in the Body of Healthy Men
This study will test how different doses of study medicine (Inno8) work in the healthy men. The purpose of this study is to prove safety of Inno8 in healthy men, which will support further development of Inno8 in people with…
- Trial name
- VOYAGER1 (NCT06649630)
- Testing
- NNC0442-0344 A
- Where
- 2 sites in Germany
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
In the United States, the majority of first-trimester surgical abortions are performed in outpatient clinics that utilize a wide variety of oral and intravenous regimens for pain control.
- Trial name
- NCT01011634
- Testing
- Intravenous moderate sedation versus oral medication
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Postoperative Pain Management After Total Hip Arthroplasty
Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion
This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center \& East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to…
- Trial name
- NCT01108562
- Testing
- Lidocaine, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Prostate Cancer
A Comparison of Totally Intravenous and Inhalation Anesthesia for Intraocular Pressure During Robot-Assisted Laparoscopic Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy (RALRP) has gained popularity during the past decade and has widely replaced conventional open prostatectomy in many institutions due to reduced blood loss, nerve sparing, less…
- Trial name
- NCT01744262
- Testing
- Total intravenous anesthesia, Inhalation Anesthesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yonsei University
TMJ Disc Disorder, Treatment
Evaluation of the Effectiveness of Arthrocentesis Using Catheter in the Treatment of Temporamandibular Joint Disorders
The study focused on arthrocentesis performed using a catheter, aiming to assess its effects on pain perception and mouth opening in patients with TMJ disorders.
- Conditions
- TMJ Disc Disorder, Treatment, Arthrocentesis
- Trial name
- NCT06766851
- Testing
- Procedure: TMJ Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
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