Clinical trials: Intravenous Fluid Therapy
Dehydration
IV NaCl (Sodium Chloride) 0.9% Vs (Versus) IV NaCl 0.9% + 5% Dextrose in Pediatric ER for Dehydration
Dehydration and refusal to eat and drink are common complaints in the Pediatric ED (Emergency Department). Most of these children have had an unsuccessful trial of oral rehydration in their community service, therefore are…
- Trial name
- NCT02054585
- Testing
- NaCl 0.9%, NaCl 0.9 +5% dextrose
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Hypokalemia, Hyponatremia
Intravenous Fluids in Hospitalised Children
The main objective of the trial is to evaluate the risk of hypokalemia following administration of a isotonic solution compared to a hypotonic solution in acutely ill hospitalised children, who need intravenous fluid therapy.
- Conditions
- Hypokalemia, Hyponatremia, Hypernatremia, Dehydration
- Trial name
- NCT02926989
- Testing
- Plasmalyte Glucos 50 mg/mL, 0.45% saline in 5% dextrose
- Where
- Finland
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Dehydration in Children, Fluid Therapy
Boluses of Ringer's in Surgical Kids (BRiSK Study)
Traditional protocols for intravenous fluid administration in children who have undergone a major abdominal or thoracic operation are based on a landmark paper published in 1957 by Holliday and Segar.
- Trial name
- BRiSK (NCT05285371)
- Testing
- Urinalysis (UA), Complete Metabolic Panel (CMP), Glucose Stick Test (d-Stick)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Migraine, Migraine in Children
Intravenous Fluids in Pediatric Migraine
The goal of this clinical trial is to compare intravenous (IV) fluids in pediatric patients with migraine. The main questions it aims to answer are: Does a large amount of fluids (bolus) improve pain Does a large amount of fluids…
- Trial name
- NCT06182098
- Testing
- 1/2 maintenance fluids, Ketorolac, Diphenhydramine
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Dayton Children's Hospital
Intravenous Fluids, Pharmacodynamics
Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers
Human digestive system physiologically ensures the absorption of oral water and hydration of the human body. Water is quickly absorbed by the digestive tract with a peak between 15 and 20 minutes.
- Conditions
- Intravenous Fluids, Pharmacodynamics, Fluid Therapy, Fluid Responsiveness
- Trial name
- WATERNAL (NCT05153837)
- Testing
- saline intravenous administration, oral water
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Gamification
Educational Escape Room Game and Nursing Students
This study will be conducted to determine the effect of educational escape room teaching on nursing students' skills in calculating intravenous drug dosage and applying fluid therapy.
- Trial name
- NCT06451926
- Testing
- Escape room game
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Şırnak Üniversitesi
Sepsis, Fluid Overload
Investigation of Novel and Established Therapies in a Human Intravenous Lipopolysaccharide Model of Sepsis
Sepsis is a common and life-threatening condition caused by a dysregulated host immune response to infection. Given the prominent role of endothelial breakdown and dysfunction in sepsis, therefore, there is an urgent need to…
- Conditions
- Sepsis, Fluid Overload, Endothelial Dysfunction, Microcirculation
- Trial name
- INITIALISE (NCT06626984)
- Testing
- Imatinib, Compound sodium lactate solution
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Fluid Shifts, Body Fluid Compartments
Body Composition Monitoring for Determination of the Fluid Status in Volunteers Undergoing Intravenous Fluid Therapy
This volunteer study tests a recently developed whole-body bioimpedance spectroscopy device called Body Composition Monitor (BCM) which measures the body composition (i.e. the water content of the body).
- Trial name
- BCM_Volunteer (NCT02296294)
- Testing
- Elo-mel® (Fresenius Kabi Austria), Body Composition Monitoring
- Where
- Austria
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna