Clinical trials: Intravenous Infusions
Healthy Volunteers, Heart Failure
A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants
This study is being done to understand how much of the medicine (CDR132L) enters the bloodstream after injection under the skin compared to injection into a vein in healthy people.
- Trial name
- NCT07656454
- Testing
- CDR132L (i.v.), CDR132L (s.c.)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Drug Overdose
Bioavailability of Nasal Naloxone and Injected Naloxone Compared
Opioid overdoses have in the last decade counted for about 230 untimely deaths annually in Norway. The government is currently implementing a strategy for combating this epidemic.
- Trial name
- OPI-15-002 (NCT02598856)
- Testing
- Intranasal (IN) naloxone 1x, Intranasal (IN) naloxone 2, Intravenous (IV) naloxone
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Ophthalmic, Surgery
Comparison of Desflurane Anesthesia Versus TIVA-TCI in Patients Undergoing Ophthalmic Ambulatory Surgery
This is a single-center, randomized, prospective research which aims to investigate the advantages and disadvantages between desflurane balanced anesthesia and TIVA-TCI with propofol in ophthalmic ambulatory surgery, so that to…
- Conditions
- Ophthalmic, Surgery, Anesthesia
- Trial name
- NCT02922660
- Testing
- desflurane, total intravenous anesthesia, inhalation anesthesia
- Where
- China
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Xiaoliang Gan
Pain
Pharmacokinetic Study of Single and Multiple Intravenous Administration of Nalbuphine Hydrochloride Injection in Healthy Chinese Volunteers
Objective：To evaluate the pharmacokinetic characteristics and safety of single and multiple intravenous injections of nalbuphine hydrochloride injection in healthy subjects.
- Trial name
- NCT06902103
- Testing
- Nabufine Hydrochloride Injection
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd
Thrombosis
Safety, Pharmacokinetics, and Pharmacodynamics of ARC1779 in Healthy Volunteers
The purpose of this study is to establish the overall safety and tolerability of ARC1779 in healthy volunteers, and to characterize its pharmacokinetic and pharmacodynamic profile with respect to parameters of platelet function…
- Trial name
- NCT00432770
- Testing
- ARC1779
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Archemix Corp.
Anemia, Pregnancy Complications
Intravenous Versus Oral Iron in Late Pregnancy: Results of Treatment
The purpose of this study is to compare the efficacy of body iron storage replenishment between low dose intravenous iron and oral iron in late pregnancy.
- Trial name
- EIVF (NCT00746551)
- Testing
- Ferli-6® (Continental Pharm co., ltd.), Venofer® (Vifor AG, St. Gallen, Switzerland)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hypothermia
Amino Acid Infusion in Mothers Before and During Cesarean Delivery
Introduction: Intravenous infusion of amino acids during cesarean delivery in mothers and neonates improves neonatal growth. Amino acid before and during anesthesia also prevents hypothermia and associated untoward effects.
- Trial name
- NCT02575170
- Testing
- Amino acid solution, Ringer's lactate solution
- Where
- Nepal
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Myocardial Infarction
Intravenous MSC Therapy on Ischemia-Reperfusion Injury in Patients With Myocardial Infarction
The investigators scheduled to assess the value of intravenous injection of WJ-MSC in patients with ST-segment elevation myocardial infarction (STEMI).
- Trial name
- NCT03533153
- Testing
- WJ-MSC cells implantation, CTSTMD PBS without WJ-MSC, Conventional drug therapy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
THCCOOH, Pharmacokinetics
Pharmacokinetics of THCCOOH and Its Acyl-glucuronide After Intravenous Administration of THCCOOH
A study on the fate and elimination of 11-Nor-Delta9-carboxy-9-tetrahydrocannabinol was up to now not conducted, except of one single experiment in which (lacking) psychopharmacological activity was tested after intravenous…
- Conditions
- THCCOOH, Pharmacokinetics, Metabolism, Cannabis
- Trial name
- NCT00176085
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Multiple Sclerosis (MS)
A Study to Evaluate the Safety, Tolerability, Kinetics, Biodistribution and Repeatability of 11C-BMS-986196 After Intravenous (IV) Administration in Healthy Participants and After Repeat IV Administration in Participants With Multiple Sclerosis
The purpose of this study is to evaluate the safety, tolerability, kinetics, biodistribution and central nervous system signal of 11C-BMS-986196 after intravenous (IV) administration in healthy participants and after repeat IV…
- Trial name
- NCT05064436
- Testing
- 11C-BMS-986196
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy Participants
A Multiple Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SRK-001 in Healthy Participants
The purpose of the study is to evaluate safety, tolerability, and pharmacokinetics (PK) of SRK-001 in Healthy Participants.
- Trial name
- NCT05156034
- Testing
- SRK-001
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sarkana Pharma Inc
Cirrhosis
Sensitivity of Alternative NRL972 Detection Methods in Healthy Subjects
The disposition of NRL972 after a 15-second intravenous injection of 2 mg NRL972 is distinctly slower in patients with hepatic cirrhosis and acute hepatitis than in healthy control subjects.
- Trial name
- NCT01164332
- Testing
- NRL972
- Where
- Hungary
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Norgine
Healthy
To Study the Absorption, Distribution, Metabolism and Excretion of AZD1305
The purpose of this study is to learn more about how AZD1305 is handled by the body, i.e the absorption, distribution, metabolism and excretion of AZD1305.
- Trial name
- NCT00689247
- Testing
- AZD1305
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Ischemia-reperfusion Injury
A Study to Evaluate the Safety and Pharmacokinetics of BX-001N in Healthy Participants
This is a randomized, double-blind, placebo-controlled, single and multiple ascending dose, Phase 1 study to evaluate the safety, tolerability, and pharmacokinetics of BX-001N after intravenous administration in approximately 64…
- Trial name
- NCT06097702
- Testing
- BX-001N Part 1, BX-001N Part 2
- Where
- Australia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Bilix Co.,Ltd.
Healthy
Safety, Tolerability and Pharmacokinetics Study of BI 1744 CL in Healthy Male Subjects
To investigate safety, tolerability, and pharmacokinetics (PK) of single i.v. doses of BI 1744 CL
- Trial name
- NCT02172131
- Testing
- BI 1744 CL
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hepatic Insufficiency
Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride
A Phase I clinical study to compare the pharmacokinetics, pharmacokinetics, and safety of intravenous administration of methoxyetomidate hydrochloride for injection in subjects with mild hepatic insufficiency (Child-pugh A)…
- Trial name
- NCT06176716
- Testing
- ET-26
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Obstetric Labour, Premature, Premature Labor
Absorption, Distribution, Metabolism And Excretion Study For GSK221149A
This is a phase one study investigating the absorption, distribution, metabolism and excretion of GSK221149A in six healthy women of non-child bearing potential.
- Trial name
- NCT00457925
- Testing
- GSK221149A
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Participants
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics Following Intravenous Administration of IRX-010 in Healthy Participants
The purpose of the study is to evaluate the safety, tolerability and pharmacokinetics with intravenous(IV) administration of IRX-010 in Healthy Participants.
- Trial name
- NCT06356259
- Testing
- IRX-010
- Where
- Netherlands
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- ImmunoRx Pharma Inc.
Postpartum Hemorrhage, Vaginal Lacerations
Tranexamic Acid for Postpartum Vaginal Laceration Hemorrhage
The necessary information was provided to the patients included in the study and their written consent was obtained.
- Trial name
- NCT07094399
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Harran University
Ebola Virus Infection
Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study of Intravenous (IV) TKM-100201 Infusion
This is a phase 1, single-center, placebo-controlled, single-blind, first-in-human, single-ascending dose study with additional multiple-ascending dose cohorts in healthy male and female volunteers.
- Trial name
- NCT01518881
- Testing
- TKM-100201
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Arbutus Biopharma Corporation