Clinical trials: Intravenous Injections
ASA 1-2 Requiring Intravenous Cannulation for General Anaesthesia
Pain of Injection of Lipuro Propofol in Children Aged 1-7 Years
Randomised controlled trial of pain of injection of lipuro in children age 1-7 versus the pain of injection of the standard formulation
- Trial name
- NCT00232895
- Testing
- lipuro propofol, standard formulation propofol
- Where
- United Kingdom
- Sponsor
- Institute of Child Health
Pain, Fear
Distraction Using VR for Children During IV in an Emergency Department
Exploring the use of virtual reality as a distracting intervention strategy for school-age children to receive intravenous placement in emergency department, and further understand the effectiveness of reducing pain and fear…
- Trial name
- NCT04081935
- Testing
- Virtual Reality
- Where
- Taiwan
- Volunteers
- 136 people
- Sponsor
- National Yang Ming Chiao Tung University
Nausea With Vomiting Chemotherapy-Induced
Buccal Film Versus IV Injection Palonosetron for Moderately Emetogenic Chemotherapy Induced Nausea and Vomiting
Phase 2 study to compare efficacy, safety and PK of palonosetron, a long acting 5-HT3 receptor antagonist, by buccal film delivery compared to iv injection for chemotherapy induced nausea or vomiting (CINV).
- Trial name
- NCT04592198
- Testing
- Palonosetron Hydrochloride Buccal Film 0.25 Mg, Palonosetron Hydrochloride Buccal Film 0.5 Mg, Palonosetron Hydrochloride, 0.25 Mg/5 mL Intravenous Solution
- Where
- 7 sites in United States
- Volunteers
- 22 people
- Sponsor
- Xiamen LP Pharmaceutical Co., Ltd
Alzheimer's Disease
SLS-005 (Trehalose Injection) in the Treatment of Alzheimer's Disease
An open-label, proof-of-concept study to evaluate the safety and treatment effects of SLS-005 in Participants with Alzheimer's Disease (AD) treated once or twice weekly for 52 weeks.
- Trial name
- [STRIVE-AD] (NCT05332678)
- Testing
- SLS-005 - Once Weekly, SLS-005 - Twice Weekly
- Where
- 3 sites in Australia
- Sponsor
- Seelos Therapeutics, Inc.
Injections, Intravenous, Administration, Intravenous
A Trial to Demonstrate the Safety and Efficacy of the OptiVein IV Catheter In a Pediatric Population
A prospective, single-center, open-label, randomized controlled trial to demonstrate the safety and efficacy of the OptiVein IV Catheter in the pediatric population.
- Trial name
- NCT03145519
- Testing
- Vasofix Certo Catheter, OptiVein Catheter
- Where
- Estonia
- Volunteers
- 188 people
- Sponsor
- Optomeditech Oy
Trigeminal Neuralgia, Facial Pain
Incidence of Intravascular (IV) Injection During Trigeminal Nerve Blocks
The purpose of this study is to investigate the incidence of intravascular injection during trigeminal nerve blocks.
- Conditions
- Trigeminal Neuralgia, Facial Pain, Postherpetic Neuralgia, Cluster Headache
- Trial name
- NCT04467398
- Testing
- trigeminal nerve block
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University
Healthy
A Study to Compare the Bioavailability and Pharmacokinetics of Cyclosporine After Intravenous Administration of NEUROSTAT®, a CREMOPHOR® EL-free Lipid Emulsion, and SANDIMMUNE® Injection (a Suspension of Cyclosporine in CREMOPHOR® EL) in Healthy Volunteers
To compare the bioavailability, pharmacokinetic profiles and the tolerability of two formulations of intravenous cyclosporine in healthy volunteers.
- Trial name
- NCT01692834
- Testing
- Sandimmune® Injection, NeuroSTAT®
- Where
- South Africa
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- NeuroVive Pharmaceutical AB
Prostate Cancer
Comparing PET-CT Using C-11 Choline and 18F-Fluoromethylcholine in Patients With Metastatic Prostate Cancer
RATIONALE: Diagnostic procedures, such as positron emission tomography (PET) and computed tomography (CT) imaging, may help find and diagnose metastatic prostate cancer.
- Trial name
- NCT01132599
- Testing
- C-11 choline, 18F-fluoromethylcholine
- Where
- United Kingdom
- Sponsor
- Cancer Research UK
Multiple Sclerosis
Evaluation of Autologous Mesenchymal Stem Cell Transplantation (Effects and Side Effects) in Multiple Sclerosis
Multiple sclerosis is a multifocal inflammatory disease of the central nervous system which affects young individuals and causes paralysis of the limbs, sensation, visual and sphincter problems.
- Trial name
- NCT01377870
- Testing
- intravenous injection of mesenchymal stem cells, injection of cell free media
- Where
- Iran
- Volunteers
- 22 people
- Sponsor
- Royan Institute
First in Man Study to Evaluate Initial Safety
Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease
The purpose of this first-in-human (FIH) study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of GL-0719 following single intravenous (IV) and subcutaneous injection (SC) doses in…
- Trial name
- NCT05318534
- Testing
- GL-0719
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gliknik Inc.
Acute Urticaria
Pilot Phase III Clinical Trial of JDP-205 IV Injection for Treatment of Acute Urticaria
This is a multicenter, parallel group, randomized, double-blind pilot Phase III clinical study of JDP-205 (cetirizine) injection, versus diphenhydramine injection, 50 mg/mL (Benadryl or generic equivalent), in approximately 36…
- Trial name
- NCT02023164
- Testing
- JDP-205 Injection, Diphenhydramine
- Where
- 6 sites in United States, Canada
- Volunteers
- 36 people
- Sponsor
- JDP Therapeutics, Inc.
HIV Infections, Substance Use Disorders
Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation
The goal of this clinical trial is to evaluate the effectiveness of a social network intervention to recruit people who inject drugs and their networks for HIV testing and linkage to HIV prevention and treatment services in…
- Conditions
- HIV Infections, Substance Use Disorders, Addiction, Opioid Use
- Trial name
- NCT06103370
- Testing
- Peer-educator-based network
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Peripheral Intravenous Phlebitis, Injection Site Pain
Ice Application for Oxacillin-Related Phlebitis and Pain
This randomized controlled trial evaluated whether ice application could reduce pain and peripheral intravenous phlebitis associated with oxacillin administration.
- Conditions
- Peripheral Intravenous Phlebitis, Injection Site Pain, Pain
- Trial name
- NCT07820956
- Testing
- Ice Application, Room-Temperature Water-Bag Application
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Central Taiwan University of Science and Technology
Nicotine Dependence, Drug Abuse
Effects of Nicotine on Brain Activity as Measured by fMRI
Background: Nicotine addiction is common among people who smoke tobacco, and the addictive properties of nicotine make smoking cessation difficult even for people who want to quit.
- Trial name
- NCT01037153
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Severe Hemophilia A
Study of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Subjects With Severe Hemophilia A
The study is to investigate the safety, tolerability, and pharmacokinetics (the determination of the concentration of the administered drug in blood over time) of recombinant Factor VIII Fc fusion protein (rFVIIIFc) in…
- Trial name
- NCT01027377
- Testing
- rFVIIIFc
- Where
- 7 sites in United States, Hong Kong and 1 more
- Volunteers
- 16 people
- Sponsor
- Bioverativ Therapeutics Inc.
Advanced Malignant Solid Tumor
A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of VG2025 Intravenous Injection in Subjects With Advanced Solid Tumors
VG2025 is a Recombinant Human IL12/15 Dual-Regulated Oncolytic HSV-1 Injection. This Phase I study will be conducted in herpes simplex virus (HSV) -seropositive subjects with advanced malignant solid tumors that are refractory to…
- Trial name
- NCT07682870
- Testing
- Recombinant Human IL12/15 Dual-Regulated Oncolytic HSV-1 Injection
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Virogin Biotech Ltd.
Obstetrical Hemorrhage
Can we Use Intravenous Injection of Tranexamic Acid in Routine Practice With Active Management of the Third Stage of Labor?
Obstetrical hemorrhage accounts for nearly one quarter of all maternal deaths worldwide and was the most common cause of maternal death in the Turkey [1,2].
- Trial name
- NCT01338454
- Testing
- transamin
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Duchenne Muscular Dystrophy (DMD)
Evaluation of the Safety, Tolerability, and Efficacy of LE051 in Patients With Duchenne Muscular Dystrophy
The purpose of this study is to evaluate the safety, tolerability, and efficacy of LE051 intravenous therapy in DMD patients treated with exon 51 skipping therapy.
- Trial name
- NCT06900049
- Testing
- LE051
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Migraine Disorders, Headache
The Effect of Intravenous Fluid Therapy in Acute Migraine Attacks
The study is a single-center, double-blind, randomized protocol comparison. The study will be conducted in Marmara University School of Medicine Pendik Training and Research Hospital, Department of Emergency Medicine between…
- Conditions
- Migraine Disorders, Headache, Acute Pain
- Trial name
- NCT04287140
- Testing
- Bolus fluid administration
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Vestibular Schwannoma, Neurofibromatosis Type 2
Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
1)Preliminarily evaluate the treatment effect of continuous vein injection of recombinant human endostatin on NF2; 2)Preliminarily evaluate the safety and the patient's tolerance of the treatment of endostatin; 3)Provide an…
- Trial name
- Endostatin (NCT02104323)
- Testing
- Endostatin
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Tiantan Hospital