Clinical trials: Intravitreal Injections
Pain, Intravitreal Injection
Pain Reduction With Topical Bromfenac Versus Artificial Tear After Intravitreal Injection.
The purpose of this prospective interventional study is to compare post-intravitreal injection pain between eyes receiving topical bromfenac versus artificial tears as an analgesic after intravitreal injection.
- Conditions
- Pain, Intravitreal Injection, Pain, Acute
- Trial name
- NCT06130384
- Testing
- Use of bromfenac 0.09% to reduce intravitreal injection pain, Use of artificial tears to reduce intravitreal injection pain
- Where
- 5 sites in United States, Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Intravitreal Injection, Ocular Rinse
The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections
This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.
- Conditions
- Intravitreal Injection, Ocular Rinse, Age-Related Macular Degeneration, Diabetic Macular Edema
- Trial name
- NCT05615805
- Testing
- OSDI questionnaire, SPEEDII questionnaire
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Intravitreal Injection, Pain
Comfort Comparison of Intravitreal Injection Eyelid Retraction Techniques
This study evaluated the discomfort associated with eyelid retraction during intravitreal injections. Participants had eyelid retraction with one of three methods: eyelid speculum, unimanual eyelid retraction method or with a…
- Trial name
- Eyelid RETRACT (NCT04144985)
- Testing
- Visual analog scale (VAS) of pain to evaluate the discomfort participants experience.
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Pain Control During Intravitreal Injections
Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections
Intravitreal injections are an efficient method of delivering therapeutic levels of medications to the posterior segment of the eye. Prior to receiving an injection, there are various methods to provide ocular anesthesia.
- Trial name
- Eyebrator (NCT03079713)
- Testing
- Handheld vibrator triggered during intravitreal injection for wet ARMD, Normal eye esthesiometry with and without vibration, Handheld vibrator not triggered during intravitreal injection for wet ARMD
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Intraocular Pressure Change in Intravitreal Injection
Effect of Antiglaucoma Agents on Short Term Intraocular Pressure Fluctuations After Intravitreal Bevacizumab Injection
To assess the effect of prophylactic antiglaucoma agents in prevention of acute intraocular pressure rise after intravitreal injection.
- Trial name
- NCT02140450
- Testing
- Timolol, Brimonidine, Acetazolamide
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences