Clinical trials: Intrinsic Capacity
Frailty in Older Adults, Intrinsic Capacity
Optimizing INtrinsic Capacity for Functional INdependence and to Impede FrailTY in Older Adults: Adaptation of the WHO-ICOPE for Healthy Ageing in Singapore
The goal of this intervention study is to screen and identify frailty and decline in intrinsic capacity (physical and mental capacities) in community-dwelling older adults in Singapore, and to evaluate whether early…
- Conditions
- Frailty in Older Adults, Intrinsic Capacity, Age-related Functional Decline, Healthy Ageing
- Trial name
- INFINITY-ICOPE (NCT07477561)
- Testing
- INFINITY-ICOPE programme
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Healthy, Body Weight
The Effect of Body Composition on Respiratory Parameters, Functional Capacity and Sleep in Healthy Young Adults
Body composition has a significant effect on the respiratory system. Both respiratory prediction of function and a prognostic tool evaluated in the cardiopulmonary system factor.
- Trial name
- NCT06507969
- Testing
- The Effect of Body Composition on Respiratory Parameters, Functional Capacity and Sleep in Healthy Young Adults
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Physical Inactivity
Comparison of the Effects of Green Exercise Programs Including Resistance and Aerobic Exercises
It was aimed to evaluate the effects of aerobic exercise and resistance exercises performed together with aerobic exercise, applied in the concept of green exercise with a multidisciplinary team (specialist doctors…
- Trial name
- GREENCITY (NCT05958745)
- Testing
- Aerobic Exercise, Aerobic + resistance exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Frailty, Frailty Syndrome
Maintaining and imPrOving the intrinSIc capaciTy Involving Primary Care and caregiVErs
The POSITIVE platform offers the possibility of unsupervised monitoring of pre-frailty and frailty status in a community setting, to detect the onset of frailty and to assess its evolution.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- POSITIVE (NCT04592146)
- Testing
- Frailty multicomponent intervention supported by POSITIVE, Frailty multicomponent intervention
- Where
- 3 sites in Poland, Spain and 1 more
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario Getafe
Community-dwelling Elderly
Exploring the Relationship Between ICOPE Framework and Frailty Among Community-dwelling Elderly Individuals
This study aims to (1) compare the assessment outcome of the ICOPE-I and ICOPE-S, and (2) investigate the correlation between both versions of the ICOPE step 1 screening tools and frailty in Taiwan.
- Trial name
- NCT06140212
- Testing
- Montreal Cognitive Assessment (MoCA), Chinese ICOPE screening tool (self-administration and interview versions), Frailty status assessment (Edmonton frail scale and Frailty criteria by Dr. Fried)
- Where
- Taiwan
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy Ageing
Multicomponent Exercise Program on the Intrinsic Capacity (ICOPE) of Community-dwelling Older Adults in Primary Care
A three-branch multi-center randomized clinical trial to be conducted in 6 public Primary Care centers located in the city of Madrid (Spain).
- Trial name
- NCT05744492
- Testing
- Vivifrail multicomponent exercise program
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- European University Spain
Frailty Syndrome, COVID-19
Implementation of the Integrated Care of Older People App and ICOPE Monitor in Primary Care (ICOPE)
Introduction: The World Health Organization has launched the INSPIRE-ICOPE-CARE program towards healthy aging. It includes "intrinsic capacity", defined as "the composite of all the physical and mental capacities of an…
- Conditions
- Frailty Syndrome, COVID-19, Healthy Aging, Old Age; Debility
- Trial name
- ICOPE (NCT04413877)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Liege
Healthy, Healthy Adult
Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in healthy individuals, who live permanently >2600m.
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801950
- Testing
- Descent from 2850m to sea level and re-ascent back to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Frailty, Older Adults
+AGIL Barcelona: Integrated Care for Community-Dwelling Frail Older Adults
The goal of this clinical trial is to evaluate the effectiveness of the +AGIL Barcelona program in helping older adults improve their physical abilities and delay disability.
- Conditions
- Frailty, Older Adults, Healthy Aging
- Trial name
- +AGIL (NCT06836167)
- Testing
- exercise promotion, review medication, promoting healthy aging
- Where
- 3 sites in Spain
- Volunteers
- 396 people
- Sponsor
- Parc Sanitari Pere Virgili
Down Syndrome, Sleep Apnea, Obstructive
19/5000 (SYNAPSOT21) Predictive Factors of Sleep Apnea Syndrome in Down Syndrome
The obstructive sleep apnea syndrome (OSAS) is frequently reported in subjects with trisomy 21. The consequences of this syndrome are expressed in various disorders such as cognitive and cardiovascular alterations.
- Conditions
- Down Syndrome, Sleep Apnea, Obstructive, Polysomnography
- Trial name
- SYNAPSOT21 (NCT03445962)
- Testing
- Assessment of OSAS predictive factors
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Frailty, Sarcopenia
Resistance-Based Multicomponent Training Plus Nutrition Supplementation for Intrinsic Capacity and Disability Risk in Chinese Rural Older Adults
This study is a five-arm, parallel-group, assessor-blinded randomized controlled trial designed to evaluate the effects of resistance-dominant multicomponent training combined with nutritional supplementation on intrinsic…
- Conditions
- Frailty, Sarcopenia, Mobility Limitation, Nutritional Risk
- Trial name
- NCT07660653
- Testing
- Routine Health Education, Leucine-Enriched Whey Protein and Vitamin D Supplementation, Progressive Resistance Training
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Capital University of Physical Education and Sports, China
Multiple Sclerosis
Cognitive Functions in Patients With Multiple Sclerosis
Approximately 65% of multiple sclerosis (MS) patients appear to have problems in their cognitive function. Long-term memory is one of the most frequently affected functions in MS patients.
- Trial name
- NCT03594357
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Gazi University
Frailty
Intrinsic Capacity and Functional Ability Monitoring With an Integrated Data Eco-System for Healthy Ageing.
In this study, 120 older adults (aged 65 years or older) either patients undergoing rehabilitation or older nursing home residents will be provided with an Eforto® device and the eco-System for Healthy Ageing (ISHA) mobile…
- Trial name
- ISHA (NCT06270979)
- Testing
- ISHA
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Ivan Bautmans
Valve Heart Disease, Awakening Early
Prospective Evaluation of Volatile Sedation After Heart Valve Surgery
Cardiac surgery is a complex operative procedure with a substantial risk of postoperative complications, so that patients undergoing valve surgery are usually transferred to the intensive care unit postoperatively.
- Trial name
- NCT04958668
- Testing
- Post-operative intensive care using volatile sedation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Goethe University
Obstructive Sleep Apnea, Obesity
Exercise Capacity and Daily Physical Activity in Obese Subjects With Treated Obstructive Sleep Apnea
Obesity is very common worldwide and breathing problems at night (obstructive sleep apnea, OSA) are common in obesity. Despite the best treatment, obesity and OSA are linked to early death from heart problems.
- Trial name
- NCT01930513
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- West Park Healthcare Centre
Falls, Frailty
VIVI-OLIVE: Multicomponent Exercise and Extra Virgin Olive Oil in Older Adults at High Risk of Falls
VIVI-OLIVE is a multicenter randomized clinical trial evaluating whether a 24-month intervention combining an individualized multicomponent exercise program (VIVIFRAIL), Mediterranean diet counselling, and supplementation with 60…
- Trial name
- VIVI-OLIVE (NCT07829484)
- Testing
- VIVIFRAIL multicomponent exercise program, Mediterranean diet counselling, Extra virgin olive oil supplementation
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundacion Miguel Servet
Dementia
The Effects of an Empower_ICE-Fit Program in PLwD Living at Home
The purpose of this study is to see if the Empower-ICE_Fit program can help people with dementia live more safely, comfortably, and independently at home.
- Trial name
- NCT07889635
- Testing
- empowerment-based Intrinsic capacity-Environment Fit, Usual Care Group
- Where
- 2 sites in China
- Volunteers
- 304 people
- Sponsor
- The University of Hong Kong
Obesity Hypoventilation Syndrome (OHS), Hypoventilation
Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation Syndrome
Obesity Hypoventilation Syndrome is defined as a combination of obesity (BMI ≥ 30 kg/m2) and daytime hypercapnia in arterial blood gas analysis (PaCO2 > 45 mmHg) without other pathologies that cause hypoventilation.
- Conditions
- Obesity Hypoventilation Syndrome (OHS), Hypoventilation, Obesity, Respiration Disorders
- Trial name
- NCT05398068
- Testing
- Exercises and Diet, Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Frailty Syndrome, Sarcopenia
Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults
This multicenter randomized controlled trial aims to evaluate the effectiveness of a playful multicomponent exercise intervention (FEXO - Fun Exercise for Older Adults) on intrinsic capacity, frailty, and functional health in…
- Trial name
- FEXO-FRAIL (NCT07133581)
- Testing
- FEXO (Fun Exercise for Older Adults)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Fall Risk
A HAPA-based Multicomponent Fall Intervention on Older Adults With Declines in Intrinsic Capacity in Nursing Homes
Falls are a common geriatric syndrome that impedes healthy aging and are the primary cause of accidental death in older adults. Globally, more than 50% of older adults experience falls in nursing homes each year.
- Trial name
- HAPA (NCT05891782)
- Testing
- HAPA-based Multidomain Fall Risk Management, Regular health education lectures
- Where
- China
- Volunteers
- 100 people
- Sponsor
- ZHANG Qing-hua