Clinical trials: Intrusive Memories
Post-traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s)
Eye Movement Intervention With Different Memory Reactivation Procedures for Intrusive Traumatic Memories
Post-Traumatic Stress Disorder (PTSD) and trauma-related symptoms are often characterized by recurrent intrusive memories that cause distress and interfere with daily functioning.
- Trial name
- NCT07767396
- Testing
- Unconscious Trauma Reactivation plus Eye Movements, Active Trauma Memory Reactivation plus Eye Movements, Neutral Memory Reactivation plus Eye Movements
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Shaanxi Normal University
Working Memory, Consolidation/Recconsolidation Memory
Theories of Working Memory and Consolidation/RECOnsolidation in the Process of Resorption of Post-traumatic Symptoms.
EMDR is a psychotherapeutic approach recommended by the World Health Organization (WHO) for the treatment of disorders such as post-traumatic stress disorder, anxiety, depression and, more generally, psychological distress.
- Conditions
- Working Memory, Consolidation/Recconsolidation Memory, Eye Movement Desensitization and Reprocessing, Alterning Bilateral Stimulation
- Trial name
- NCT06469333
- Testing
- Eye movements (EM), Auditory stimulations, Tactile stimulations
- Where
- France
- Volunteers
- 154 people
- Sponsor
- University of Lorraine
Post-traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s)
Tetris Intervention Following Subliminal Reactivation for Intrusive Memories
Intrusive memories of traumatic events are a core feature of Post-Traumatic Stress Disorder (PTSD) and can cause substantial distress and functional impairment.
- Trial name
- NCT07495917
- Testing
- Subliminal Reactivation Followed by Visuospatial Interference, Computer-based Visuospatial Task (Tetris)
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Shaanxi Normal University
Post-Traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s)
A Digital Cognitive Intervention for Intrusive Memories After Trauma
Intrusive traumatic memories frequently trigger severe distress and psychological disorders such as post-traumatic stress disorder (PTSD).
- Trial name
- NCT07523360
- Testing
- Pre-selected Trauma-related Cue Images with Eye Movement, Patient-provided Trauma-related Cue Images with Eye Movement, Neutral Images with Eye Movement
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Zhu Zijian
Intrusive Memories of Traumatic Event(s)
A Brief Cognitive Task Intervention for NHS Staff Affected by COVID-19 Trauma (GAINS-2 Study)
Frontline healthcare staff are frequently exposed to traumatic events at work (e.g., witnessing patients die), amplified by the COVID-19 pandemic.
- Trial name
- GAINS-2 (NCT05616676)
- Testing
- Brief digital imagery-competing task, Brief digital music-listening task, Treatment As Usual
- Where
- United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- P1vital Products Limited
Intrusive Memories of Traumatic Event(s)
The Lóa Study: A Brief Digital Intervention for Women With Intrusive Memories in the SAGA Cohort
Intrusive memories are sensory memories of a traumatic event(s) that spring to mind involuntarily, and can evoke strong emotions and disrupt functioning in daily life.
- Trial name
- NCT05849337
- Testing
- Brief imagery-competing task, Brief psychoeducation and signposting task, Treatment as usual (TAU)
- Where
- Iceland
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Iceland
PTSD, Intrusive Memories
Estradiol and Intrusive Memories
The aim of the current project is to investigate the impact of 3mg of oral estradiol valerate on the formation of intrusive memories after analog trauma.
- Conditions
- PTSD, Intrusive Memories, Intrusion Symptom, Trauma
- Trial name
- EstraMemo (NCT07419594)
- Testing
- Estradiol Valerate
- Where
- Germany
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Posttraumatic Stress Disorder, Intrusive Traumatic Memories
Tackling Intrusive Traumatic Memories After Childbirth
This single-blind waitlist randomized controlled trial aims to investigate the efficacy of a single-session behavioral intervention composed of a brief evocation of the childbirth memory followed by a visuospatial task (the…
- Trial name
- ASTRAL (NCT05381155)
- Testing
- A single-session behavioral intervention composed of a brief evocation of the childbirth memory followed by a Tetris gameplay
- Where
- 2 sites in Switzerland
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Intrusive Memories of Traumatic Event(s)
A Brief GAmeplay Intervention for NHS ICU Staff Affected by COVID-19 Trauma (GAINS Study)
Intensive care unit (ICU) staff are frequently exposed to traumatic events at work (e.g., witnessing patients die), amplified by the COVID-19 pandemic.
- Trial name
- GAINS (NCT04992390)
- Testing
- Brief digital imagery-competing task intervention
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- P1vital Products Limited
Intrusive Memories
The Effect of Dronabinol on the Acquisition and Consolidation of Trauma-Associated Memories
The aim of the current project is to investigate the impact of an activation of the cannabinoid system with an exogenous cannabinoid dronabinol (delta-9-tetrahydrocannabinol) on the formation of intrusive memories after analog…
- Trial name
- NCT04871269
- Testing
- Dronabinol
- Where
- Germany
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Sleep, Intrusive Memories
Sleep and Wellbeing Study
Most people will experience a psychologically traumatic event, such as a life-threatening accident, at some point in their life.
- Conditions
- Sleep, Intrusive Memories, Posttraumatic Stress Disorder
- Trial name
- NCT03012685
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Oxford
PTSD - Post Traumatic Stress Disorder, Intrusive Memories of Traumatic Event(s)
Neuromodulation of the Hippocampus to Reduce Intrusive Re-Experiencing in PTSD: A Randomized Controlled Trial
The goal of this clinical trial is to learn if non-invasive neurostimulation of memory-related brain areas works to treat intrusive memory symptoms in adults patients with posttraumatic stress disorder (PTSD).
- Trial name
- NCT06639061
- Testing
- Hippocampal stimulation using repetitive transcranial magnetic stimulation (rTMS)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Intrusive Memories, PTSD
The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories
The purpose of the study is to examine whether oxytocin and certain polygenic risk scores affect the development of intrusive memories, a cardinal symptom of PTSD.
- Trial name
- NCT03875391
- Testing
- Oxytocin
- Where
- Germany
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Intrusive Memories, PTSD
Sleep's Influence on the Treatment of Intrusive Emotional
Intrusive memories represent a debilitating core feature of PTSD, one of the most prevalent psychiatric disorders following trauma.
- Trial name
- SLEPT (NCT05678361)
- Testing
- Sleep/Nap
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University of Zurich
Intrusive Memories of Traumatic Event(s)
Lóa Project: An Exploratory Pilot Randomised Controlled Trial of a Remotely-delivered Brief Cognitive Intervention to Reduce Intrusive Memories of Trauma for Women in Iceland
Intrusive memories are sensory memories of a traumatic event(s) that spring to mind involuntarily, evoke strong emotions, and disrupt functioning in daily life.
- Trial name
- NCT05089058
- Testing
- Brief, digitally delivered imagery-competing task intervention package, comprised of:, Brief, digitally delivered relaxation task intervention, comprised of:
- Where
- Iceland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Intrusive Memories of Traumatic Event(s), Post Traumatic Stress Disorder
Simple Cognitive Task Intervention After Trauma During COVID-19 In Hospital Staff EKUT-P RCT
This research study is designed to investigate the effects of a remotely delivered simple cognitive task (a memory cue followed by playing the computer game "Tetris" with mental rotation instructions) on intrusive memories…
- Trial name
- NCT04460014
- Testing
- Simple cognitive task intervention
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Karolinska Institutet
Intrusive Memories of Trauma, Symptom of Post Traumatic Stress Disorder (Criterion B1)
A Brief Cognitive Intervention After Intrusive Memories of Trauma With Young Refugees: An Extension
This research study is designed to investigate the use of a simple cognitive task (a memory cue and 10 minute time gap, followed by playing the computer game "Tetris") for decreasing the number of intrusive memories of trauma…
- Trial name
- NCT03760601
- Testing
- Brief cognitive intervention
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Karolinska Institutet
Intrusive Memories
Behavioral Modulation of Intrusive Memories
The purpose of the study is to examine whether sleep affects the development of intrusive memories.
- Trial name
- NCT03227081
- Testing
- Sleep Deprivation
- Where
- Germany
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Non-clinical Participants, Intrusive Memories
Understanding Reactions to Emotional Material in the Media During COVID-19 - Study 2
This second feasibility study aims to adapt a protocol usually run in the laboratory in the Psychology Department for healthy participants (including the trauma film paradigm (James et al., 2016) and a simple cognitive task…
- Trial name
- NCT05063825
- Testing
- Simple cognitive task intervention
- Where
- Sweden
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Posttraumatic Stress Disorder, Intrusive Traumatic Memories
Tackling Intrusive Traumatic Memories After a Difficult Birth
This proof-of-principle study aims to investigate the effects of a brief behavioural procedure including a computerized visuospatial task (the computer game "Tetris") preceded by a reactivation of the traumatic memory of…
- Trial name
- NCT04286724
- Testing
- Brief behavioural procedure including a computerized visuospatial task (computer game "Tetris")
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Antje Horsch