Clinical trials: Inulin
Kidney Disease
Designing a Bayesian Model of the Plasma Clearance of Calcium Edetate de Sodium for the Calculation of GFR and Validity Compared to the Renal Clearance of Inulin
Diagnosis of patients with renal insufficiency and recommendations for medical treatment of patients who suffer from chronic renal failure are based on the different stages of Glomerular Filtration Rate (GFR).
- Trial name
- DFGBay (NCT02300376)
- Testing
- Dosage of Calcium edetate de sodium
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Irritable Bowel
Effect of Rate Of Delivery on Colonic Fermentation of inuliN (EON)
To test whether slowing the rate of delivery of inulin with either psyllium or divided dosing of inulin, will reduce colonic gas production as compared to inulin combined with placebo.
- Trial name
- EON (NCT05619341)
- Testing
- psyllium, inulin
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome
Fibre and Gas in Irritable Bowel Syndrome
The aim of the study is to investigate how dietary fibre combinations affects gut physiology, particularly colonic gas production.
- Trial name
- EFIGI (NCT03265002)
- Testing
- Inulin, Psyllium, Inulin and psyllium
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Nottingham
Digestive Health, Gastrointestinal Health
The Effects of Oral Fructanase Administration on Gastrointestinal Symptoms After Inulin Challenge in Healthy Adults
The carbohydrate inulin (from chicory root) is a healthy prebiotic ingredient found in dietary supplements and fortified foods (Nagy et al).
- Conditions
- Digestive Health, Gastrointestinal Health, FODMAP Intolerance, Food Sensitivity
- Trial name
- NCT06628869
- Testing
- Fructanase
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BIO-CAT, Inc.
Metabolic Syndrome
Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome
Type 2 diabetes mellitus, insulin resistance, visceral obesity and disorders of lipid metabolism, especially triglyceride and hypertension are metabolic disorders that play a central role in pathophysiology of metabolic syndrome…
- Trial name
- NCT02778776
- Testing
- Metformin, Agave inulin
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Obesity (Disorder)
Lactobacillus Acidophilus and Inulin for Cognitive Impairment in Obesity
This randomized crossover clinical trial aims to evaluate the effect of a synbiotic containing Lactobacillus acidophilus and inulin on cognitive function in adults with obesity and mild cognitive impairment.
- Trial name
- NCT07810517
- Testing
- Synbiotic (Lactobacillus acidophilus LA-5 and Agave Inulin)
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Anahuac University
Head and Neck Squamous Cell Carcinoma
The Effect of Prebiotic Inulin on Patients Affected by R/M HNSCC Treated With Immune Checkpoint Inhibitors
The PRINCESS study is a hypothesis-generating, interventional, open-label, non pharmacological trial designed to characterize the translational and clinical implications of the regular assumptions of inulin on Gut Microbiota…
- Trial name
- PRINCESS (NCT05821751)
- Testing
- inulin, Pembrolizumab, Nivolumab
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Constipation - Functional
Evaluation of the Effect of Chicory Inulin-type Fructans in Constipated Adults
Constipation is common in the general population, especially in women and in the elderly, which can significantly affect quality of life of the individual.
- Trial name
- NCT05447481
- Testing
- chicory inulin-type fructan
- Volunteers
- 40 people
- Sponsor
- Sensus
Iron Absorption, Gut Bacteria
Effect of Inulin on Iron Absorption in Humans
Prebiotics are non-digestible food ingredients that beneficially affect the host by selectively stimulating the growth or activity of species in the colon that can improve host health.
- Trial name
- NCT01483092
- Testing
- inulin, maltodextrin
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Psoriasis
INulin-type Fructans-induced Gut Microbiota Modulation Impact on GUT-SKIN Axis Parameters in Psoriasis
There is increasing evidence of a strong, bidirectional correlation between the gut and the skin, that associates gastrointestinal health with skin homeostasis and allostasis.
- Trial name
- INGUTSKIN (NCT05971992)
- Testing
- Chicory-derived inulin-type β-fructans, Maltodextrin
- Where
- 2 sites in Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Polish Academy of Sciences
Insomnia Disorder, Sleep Initiation and Maintenance Disorders
Inulin-Spirulina Co-intervention for Insomnia Disorder
The goal of this clinical trial is to learn if inulin and spirulina, used alone or in combination, can improve insomnia disorder in adults aged 18 to 60 years with chronic insomnia disorder.
- Trial name
- NCT07537192
- Testing
- Inulin, Spirulina, Maltodextrin
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Diet, Healthy, Systemic Inflammatory Response
Effect of Pectin and Inulin Fibre Supplementation on Glucose and ANS Modulation
The study involves intake of dietary supplements, which are commonly found in the UK diet (not pharmacological agents) to test their effects on inflammation in the body and gut microbiome composition.
- Trial name
- NCT06480799
- Testing
- Fibre intervention
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elizabeth Simpson
Liver Disease Chronic, HEPATITIS C VIRUS CHRONIC INFECTION
Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study).
The purpose of this clinical trial is to evaluate whether a nutritional supplement containing resveratrol, quercetin, taurine, inulin, and whey protein improves biochemical and molecular markers, as well as clinical outcomes, in…
- Trial name
- RESQUETI (NCT07487623)
- Testing
- resveratrol, quercetin, taurine, whey protein, and inulin, whey protein
- Where
- 2 sites in Mexico
- Volunteers
- 26 people
- Sponsor
- University of Guadalajara
Inulin, IBS (Irritable Bowel Syndrome)
The Effect of Inulin Supplementation in Individuals With IBS-C
Background: This study aimed to evaluate the effects of inulin supplementation on nutritional intake, anthropometric parameters, and bowel symptoms in individuals diagnosed with IBS-C.
- Conditions
- Inulin, IBS (Irritable Bowel Syndrome), Nutritional Status, Anthropometric Measurement
- Trial name
- NCT06945302
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Obesity in Childhood
Non-Pharmacologic Alternatives for Childhood Obesity
Childhood obesity is a global health issue. Mexico has been considered as the country with the higher number of children with obesity. There are not approved drugs to support diet and exercise as the first step to lose weight.
- Trial name
- NCT03670875
- Testing
- Agave inulin, Curcumin, O3FA
- Where
- Mexico
- Volunteers
- 300 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Type 1 Diabetes Mellitus
The Effect of Uric Acid Lowering in Type 1 Diabetes
Patients with type 1 diabetes mellitus (T1DM) are at high risk of developing kidney complications potentially leading to end stage renal disease.
- Trial name
- NCT02344602
- Testing
- Febuxostat
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Acne Vulgaris
"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."
The study aims to conduct a comparative clinical evaluation of the effectiveness of a fixed topical combination of adapalene with benzoyl peroxide in the form of a gel, a fixed combination of Lactobacillus rhamnosus…
- Trial name
- NCT05855629
- Testing
- Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, Topical Adapalene, Benzoyl Peroxide Gel
- Where
- Ukraine
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Treatment and Diagnostic Center of Private Enterprise "Asklepiy"
Type 1 Diabetes Mellitus
Effect of Dietary Carbohydrate Content and Inulin-Fructooligosaccharide Supplementation on Glycemic Control in Individuals With Type 1 Diabetes Mellitus
Diabetes is a chronic metabolic disease in which nutrients such as carbohydrates, fats and proteins cannot be utilized sufficiently due to the inability to produce insulin or defects in the effect of the produced insulin.
- Trial name
- NCT07673523
- Testing
- fructooligosaccharide and inulin, Dietary carbohydrate 30%, Dietary carbohydrate 50-55%
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Healthy
Influence of Food Matrix on Prebiotic Efficacy in Inulin Type Fructans
The aim of the study is to investigate whether the food matrix has an influence on the prebiotic efficacy (bifidobacteria growth) of chicory-derived Orafti® inulin in healthy adult volunteers.
- Trial name
- NCT05581615
- Testing
- Inulin
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Evidence of Adaptation to Dietary Exposure to Fructans
Pilot Study of the Effect of Fructans on Fermentation in the Colon & Transit
Some carbohydrates (complex sugars) which are found in grains, fruit and vegetables, cannot be digested by humans. When eaten they pass through the small bowel to the large bowel, or colon.
- Trial name
- PERFECT (NCT01963364)
- Testing
- Inulin challenge, oligofructose supplement
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Nottingham