Clinical trials: Invasive Cervical Cancer
Surgical Procedures, Minimally Invasive
Comparison of Ivor Lewis and Tri-incision Approaches for Patients With Esophageal Cancer
Esophagectomy for esophageal cancer is a technically complex procedure which is associated with high perioperative mortality, even in high volume centers[1].
- Conditions
- Surgical Procedures, Minimally Invasive, Operative, Esophageal Neoplasms
- Trial name
- NCT02017002
- Testing
- Ivor Lewis, Tri-incision
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Esophageal Cancer
Esophageal Squamous Cell Cancer Surveillance With Cytosponge
Surveillance and early detection of esophageal squamous cell carcinoma with minimally-invasive Cytosponge™ cell collection device coupled with molecular biomarkers.
- Trial name
- NCT04192695
- Testing
- Cytosponge cell collection device
- Where
- Poland
- Volunteers
- 178 people
- Sponsor
- Centre of Postgraduate Medical Education
Cancer of the Head and Neck
PET With [18F]HX4 in Head and Neck Cancer
The aim of this study is to (i) Determine if tumor hypoxia can be accurately visualised with [18F] HX4 PET imaging in head and neck tumors (ii) correlate the [18F] HX4 PET images with blood and tissue markers and (iii)…
- Trial name
- NCT01347281
- Testing
- Injection of [18F]HX4
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Maastricht Radiation Oncology
Breast Cancer, Colorectal Cancer
Biological Therapy in Treating Patients With Metastatic Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. PURPOSE: Phase I trial to study the effectiveness of biological therapy in treating patients who have…
- Conditions
- Breast Cancer, Colorectal Cancer, Extrahepatic Bile Duct Cancer, Gallbladder Cancer
- Trial name
- NCT00004604
- Testing
- CEA RNA-pulsed DC cancer vaccine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Esophageal Cancer
NIF-Guided RAMIE Using ICG Versus OTE Feasibility RCT
In Canada, the incidence of esophageal cancer has been increasing over time, while surgical standards for esophageal resections have remained unchanged.
- Trial name
- RAMIE vs OTE (NCT04938973)
- Testing
- Robotic Assisted Minimally Invasive Esophagectomy (RAMIE), Open Transthoracic Esophagectomy (OTE)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Thyroid Cancer
A Study of Optical Imaging With Light From Radiotracers in Cancer Patients
The purpose of this study is to test Cerenkov luminescence imaging, which is a different way to take pictures of thyroid cancer and/or any tumors with (existing or suspected) nodal metastases in the neck, supraclavicular…
- Trial name
- NCT03484884
- Testing
- Cerenkov luminescence imaging.
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Patients Diagnosed With Advanced Carcinoma of Uterine Cervix t
Non-comparative Study of Treatment With Induction Chemotherapy With Cisplatin and Gemcitabine Followed by Chemoradiation or Definitive Chemoradiation in Invasive Locally Advanced Carcinomas of Uterine Cervix.
The purpose of this phase II study is to determine the survival free disease of patients diagnosed with invasive locally advanced carcinomas of uterine cervix treated with induction chemotherapy with cisplatin and gemcitabine…
- Trial name
- CIRCE (NCT01973101)
- Testing
- Cisplatin, Gemcitabine, Radiotherapy
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Parathyroid Gland Adenoma, Primary Hyperparathyroidism
Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyroidism
This clinical trial studies the omission of intact parathyroid hormone testing during surgery in treating patients with primary hyperparathyroidism.
- Trial name
- NCT03011736
- Testing
- Laboratory Biomarker Analysis, Parathyroidectomy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Roswell Park Cancer Institute
Cervical Cancer, High Grade Sil
Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.
Nearly 8 000 new cervical cancer cases are diagnosed in South Africa per year; many are still undiagnosed and about 50% of diagnosed cases succumb per year.
- Conditions
- Cervical Cancer, High Grade Sil, CIN2
- Trial name
- DiaVACCS (NCT02956031)
- Testing
- Screening, Colposcopy, LLETZ
- Where
- South Africa
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Pretoria
Esophageal Carcinoma
18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal Cancer
This study is being done to learn how 18F-FSPG PET/CT scan results may be related to the response to chemotherapy and radiation in patients with esophageal cancer.
- Trial name
- NCT06549413
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- M.D. Anderson Cancer Center
Neuromuscular Block, Esophageal Cancer
Deep Neuromuscular Relaxation in Patients for Thoraco-laparoscopic Esophagectomy
Rationale: Endoscopic (thoraco-laparoscopic) esophageal surgery is a high risk procedure where the use of deep neuromuscular block (NMB) may increase field visibility and anaesthesia conditions.
- Conditions
- Neuromuscular Block, Esophageal Cancer, Surgery
- Trial name
- DEPTH (NCT02320734)
- Testing
- Rocuronium
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Esophageal Cancer, Induction Chemotherapy
Phase II Trial of Neoadjuvant Treatment and Minimal Invasive Surgery for Esophageal and GEJ Cancer
Phase II trial of induction chemotherapy with carboplatin AUC 6 plus paclitaxel 175 mg/m2 in a 21 day cycle for two cycles followed by radiotherapy 4500 cGy in 25 fractions plus carboplatin AUC=2 paclitaxel 50 mg/m2 in a week…
- Trial name
- QUIMERA (NCT02924909)
- Testing
- carboplatin paclitaxel
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Thyroid Cancer
Comparison of Quality of Life in Patients with Differentiated Thyroid Carcinoma Undergoing Different Surgery
The incidence of thyroid cancer has increased rapidly in recent years, especially in women. Early differentiated thyroid cancer has a good prognosis, and surgery is the main treatment.
- Trial name
- NCT06037174
- Testing
- minimally invasive procedure, Conventional Open Surgery
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cervical Cancer
SElf-SAMpling in Cervical Cancer Screening; SESAM Study
Study aims to support development of evidence based health care in Norway through evaluating recently proposed technological improvements in cervical cancer control before their routine use.
- Trial name
- SESAM (NCT02945891)
- Testing
- HPV testing of Evalyn®Brush, FloqSwab and Colli-Pee specimens
- Where
- 4 sites in Norway
- Volunteers
- 310 people
- Sponsor
- Oslo University Hospital
Acinar Cell Carcinoma, Adenoid Cystic Carcinoma
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may…
- Conditions
- Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortical Carcinoma, Adrenal Gland Pheochromocytoma
- Trial name
- NCT02834013
- Testing
- Biospecimen Collection, Computed Tomography, Echocardiography Test
- Where
- 1,007 sites in United States, Guam
- Volunteers
- 798 people
- Sponsor
- National Cancer Institute (NCI)
Surgical Neoplasms, Abdominal Surgical Diseases
Prospective Collection and Registry Study of Multicenter, Multidisciplinary Surgical Minimally Invasive Videos
This is a prospective multicenter patient registry study. We continuously collect full-length intraoperative surgical videos from thoracoscope, laparoscope, hysteroscope, transcervical resectoscope, cystoscope, prostate…
- Conditions
- Surgical Neoplasms, Abdominal Surgical Diseases, Pelvic Surgical Diseases, Urologic Surgical Diseases
- Trial name
- VISION (NCT07752862)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Chinese Academy of Sciences
Cervical Cancer, Cervical Cancer Stage IB1
Safety of Minimally Invasive Surgery Using Endoscopic Stapler in Early Stage Cervical Cancer Patients (SOLUTION)
The SOLUTION trial aims to show the efficacy and safety of performing radical hysterectomy by minimally invasive surgery using an endoscopic stapler in patients with cervical cancer stage IB1 (FIGO staging 2009) and thus to prove…
- Conditions
- Cervical Cancer, Cervical Cancer Stage IB1, Minimally Invasive Surgery
- Trial name
- SOLUTION (NCT04370496)
- Testing
- Minimally invasive surgery using endoscopic stapler
- Where
- 3 sites in South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Cancer
Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma
RATIONALE: VEGF Trap may stop the growth of solid tumors or non-Hodgkin's lymphoma by stopping blood flow to the tumor. PURPOSE: This phase I trial is studying the side effects and best dose of intravenous VEGF Trap in treating…
- Trial name
- NCT00083213
- Testing
- ziv-aflibercept
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Regeneron Pharmaceuticals
Esophageal Cancer (EsC), Postoperative Pulmonary Complications (PPCs)
Effect of VExUS Score on Postoperative Pulmonary Complications in Elderly Patients
Brief Summary This clinical trial aims to evaluate whether perioperative goal-directed fluid therapy (GDFT) targeting a venous excess ultrasound (VExUS) score of 1 can reduce postoperative pulmonary complications (PPCs) in…
- Trial name
- NCT07691944
- Testing
- VExUS Score-Guided Intraoperative Goal-Directed Fluid Therapy
- Volunteers
- 126 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
CIN 2/3, HPV Infection
Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)
This is a phase II double blind, placebo-controlled, randomized study of Artesunate vaginal inserts for the treatment of women who have cervical high grade intraepithelial neoplasia (CIN2/3).
- Conditions
- CIN 2/3, HPV Infection, Pre-Cancerous Dysplasia, Cervical Dysplasia
- Trial name
- ART-CIN_IIB (NCT04098744)
- Testing
- Artesunate vaginal insert
- Where
- 7 sites in United States
- Volunteers
- 78 people
- Sponsor
- Frantz Viral Therapeutics, LLC