Clinical trials: Invasive Fungal Disease
Candidiasis
Early Clinical Experience With Anidulafungin In Patients With Liver Disease In The United Kingdom
The purpose of this study is to describe the real world effectiveness of anidulafungin in clinical practice in a large Liver Unit in the United Kingdom.
- Trial name
- NCT01202253
- Testing
- anidulafungin
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Pfizer
Allogeneic Haematopoietic Stem Cell Transplantation
Vaccination of Children Following Allogeneic Stem Cell Transplantation
The purpose of this study is to determine the immunogenicity and tolerability of the DTaP-IPV-HBV/Hib combination vaccine Infanrix hexa and the heptavalent pneumococcal conjugate vaccine Prevenar in pediatric recipients of…
- Trial name
- NCT00169728
- Testing
- DTaP-IPV-HBV/Hib combination vaccine, Infanrix hexa, heptavalent pneumococcal conjugate vaccine, Prevenar
- Where
- 11 sites in Germany
- Volunteers
- 53 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Aspergillosis, Invasive Fungal Infection
Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis
The purpose of this study is to compare the efficacy and safety of isavuconazole versus voriconazole in the treatment of patients with invasive aspergillosis.
- Trial name
- NCT00412893
- Testing
- Isavuconazole, Voriconazole
- Where
- 107 sites in United States, Argentina and 24 more
- Volunteers
- 527 people
- Sponsor
- Astellas Pharma Inc
Invasive Candidiasis
Pharmacokinetics of Micafungin in Patients of Intensive Care Units
Invasive fungal infections (IFIs) are a frequent cause of morbidity and mortality in high-risk patients, such as immunocompromised patients.
- Trial name
- MI-K (NCT02164890)
- Testing
- micafungin
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Candidiasis
Caspofungin to Prevent Candidiasis in Adults in Hospital Intensive Care Units
This study will examine whether the anti-fungal drug caspofungin can prevent Candida infections in adult patients in intensive care units (ICUs).
- Trial name
- NCT00099775
- Testing
- Caspofungin
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- National Cancer Institute (NCI)
Aspergillosis
Inhalation of Liposomal Amphotericin B to Prevent Invasive Aspergillosis
A Phase II/III randomized double-blind study comparing the safety and the efficacy of a weekly administration of 25 mg nebulized AmBisome with nebulized placebo solution to prevent invasive pulmonary aspergillosis in neutropenic…
- Trial name
- NCT00263315
- Testing
- nebulised liposomal amphotericin B
- Where
- 2 sites in Netherlands
- Volunteers
- 320 people
- Sponsor
- Erasmus Medical Center
Pulmonary Invasive Fungal Infections, Pulmonary Invasive Aspergillosis
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
- Trial name
- DOMINIC (NCT03827694)
- Testing
- Non-Invasive Testing for PIFI
- Where
- 33 sites in United States, Canada
- Volunteers
- 400 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Aspergillosis, Invasive Pulmonary Aspergillosis
Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects
This study aims to compare the safety, tolerability, and efficacy of voriconazole and anidulafungin in combination versus voriconazole alone in pediatric subjects aged 2 to 17 years with invasive aspergillosis.
- Conditions
- Aspergillosis, Invasive Pulmonary Aspergillosis, Neuroaspergillosis
- Trial name
- NCT01188759
- Testing
- Voriconazole, Anidulafungin
- Sponsor
- Pfizer
Plasma Administration, Invasive Fungal Infection
Association of Plasma Transfusions and Invasive Fungal Infection
Although lacking strong evidences, plasma transfusions are commonly used in critically ill neonates. To date, the relationships between plasma transfusions and nosocomial infection remain controversial and no study has reported…
- Conditions
- Plasma Administration, Invasive Fungal Infection, Neonatal Infection
- Trial name
- PT (NCT03149562)
- Testing
- plasma transfusions, non-plasma transfusions
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Candidemia, Invasive Candidiasis
Non-Conventional Microbiological Methods in the Diagnosis of Candidemia
This study evaluates the diagnostic value of non-conventional microbiological methods for early detection of candidemia and invasive candidiasis in adult hospitalized patients with suspected invasive fungal infection.
- Trial name
- NCT07422155
- Testing
- Candida Diagnostic Testing Panel
- Where
- Slovenia
- Volunteers
- 2 people
- Sponsor
- Institute of Oncology Ljubljana
Fungal Infection
Multicenter Cohort Study of Invasive Fungal Filamentous Fungal Infections in Liver Transplant Patients
Invasive filamentous fungal infections (aspergillosis, scedosporiosis, mucormycosis, fusarium wilt) are frequent and serious in immunocompromised individuals and especially in organ transplant patients.
- Trial name
- FongiFoie (NCT05150327)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Mycoses
Invasive Mould Infections in Indian ICUs - Descriptive Epidemiology, Management and Outcome
Invasive mould infections are emerging causes of morbidity and mortality in ICU patients. This is attributed to prolonged ICU stay of critically ill patients with many co-morbidities.
- Trial name
- NCT02683642
- Where
- 11 sites in India
- Volunteers
- 420 people
- Sponsor
- Fungal Infection Study Forum