Clinical trials: Investigation Time
Cancer
Phase I Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamics of GSK2256098 in Healthy Volunteers
The purpose of this study is to test the safety of a new drug and to look at how the drug is handled by your body. This is the first time the drug will be given to people, the drug has been safely given to animals over many days…
- Trial name
- FTIH (NCT00996671)
- Testing
- GSK2256098
- Where
- Australia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Erectile Dysfunction
A Study to Evaluate Intravaginal Ejaculation Time in Men With and Without Premature Ejaculation
The purpose of the study is to characterize intravaginal ejaculatory latency time (time between the start of vaginal intercourse and the start of intravaginal ejaculation) in men with and without premature ejaculation (PE) and to…
- Trial name
- NCT00210678
- Testing
- No intervention
- Volunteers
- 1,115 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Gastric Transit Time
Study to Evaluate the Efficacy of Oral Dissolving Metoclopramide Before Video Capsule Endoscopy
Summary: This study investigates the use of oral dissolving metoclopramide during standard video capsule endoscopy. Metoclopramide is a pro -motility agent, that is, this medication helps with movement through the stomach and…
- Trial name
- NCT01631994
- Testing
- metoclopramide
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Dental Anxiety in Children, Pediatric Anxiety
Aromatherapy vs Music Therapy for Anxiety in Children During Dental Radiography
This study aims to evaluate and compare the effects of aromatherapy and music therapy on anxiety levels in children undergoing intraoral radiographic examination for the first time.
- Trial name
- NCT07542665
- Testing
- Music Therapy, Aromatherapy, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Pharmacokinetics
Effect of Ketoconazole on Sufentanil NanoTab Pharmacokinetics
Evaluate the effect of taking ketoconazole on sufentanil plasma concentrations following sublingual administration of sufentanil NanoTab.
- Trial name
- NCT01721070
- Testing
- Sufentanil NanoTab (SUF NT) 15 mcg, Ketoconazole 400 mg, sufentanil NanoTab (SUF NT) 15 mcg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Talphera, Inc
Medical Scribes
Evaluation of the Use of Medical Scribes in VAMC Emergency Departments and Specialty Care Clinics
Background and study aims: Medical scribes are trained paraprofessionals that assist providers with documenting patient encounters.
- Trial name
- NCT04154462
- Testing
- Scribes
- Where
- 12 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
Alcohol Drinking, Aggression
Just-In-Time Intervention to Reduce Alcohol-Facilitated Intimate Partner Violence Perpetration
Acute alcohol intoxication is a robust predictor of intimate partner violence (IPV) perpetration for young adult men and women; therefore, interventions delivered proximally to drinking episodes - a period of high risk - are…
- Conditions
- Alcohol Drinking, Aggression, Emotion Regulation
- Trial name
- NCT05145868
- Testing
- Alcohol Skills and Emotion Regulation Intervention, Attention Control
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Neonatal Resuscitation, Heart Rate Assessment
Impact of a Mobile Application for Heart Rate Assessment in Simulated Neonatal Resuscitation
NeoTapAdvancedSupport (NeoTapAS) is a free-of-charge mobile application that showed good accuracy in HR estimation. This study aims to evaluate the impact of NeoTapAS on timing of HR communication and of resuscitation…
- Trial name
- NCT03730025
- Testing
- Auscultation plus NeoTapAS, Auscultation without NeoTapAS
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Malocclusion
Evaluation of a "Flash-free" Adhesive Resin for Orthodontic Bracket Bonding
The purpose of this study is to compare bonding time, bond survival, amount of adhesive remaining on the tooth surface after bracket debonding, and time required for adhesive remnant cleanup between a new "flash-free" and a…
- Trial name
- NCT02030002
- Testing
- APC Flash-Free Adhesive Coated Appliance System, APC II Adhesive Coated Appliance System
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Overactive Bladder, Overactive Bladder Syndrome
Experience Sampling Method in OAB Patients
Rationale: The overactive bladder syndrome is diagnosed clinically by using the ICS criteria of ≥8 micturitions and at least 1 urgency episode per 24 hours.
- Trial name
- NCT03435991
- Testing
- Validation Experience Sampling Method 'Uromate'
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sore-throat, Common Cold
A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Throat Spray on the Incidence and Duration of Sickness
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of Beekeeper's Naturals Propolis Immune Support Throat Spray on the incidence and duration of sickness over a 16-week period.
- Trial name
- NCT07246850
- Testing
- Beekeeper's Propolis Throat Spray
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beekeeper's Naturals Inc
Drug Interactions
Study to Learn More About the Effect of Itraconazole (ITZ) Given Repeatedly by Mouth on the Way How the Study Drug BAY1902607 Given One Time by Mouth Acts in the Human Body of Healthy Male Participants
BAY1902607 is a new type of drug under clinical development for different conditions including the treatment of endometriosis, i.e. a condition where the tissue that usually grows inside the womb grows outside of the womb.
- Trial name
- NCT03789890
- Testing
- BAY1902607, Itraconazole
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
Distal Radius Fracture
Prospective, Observational Clinical Investigation of the Exos Reformable Brace
This is a prospective observational single cohort trial quantifying time to radiographic union (primary endpoint) and convenience, satisfaction, pain and resource requirements (secondary) for patients with non-operatively treated…
- Trial name
- EXOS (NCT03922256)
- Testing
- molded brace
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
General Skin Cleansing
Evaluation of Chlorhexidine Gluconate Concentration on Skin of Human Subjects Following Multiple Application Times
This study will evaluate the amount of chlorhexidine gluconate (CHG) present on treated skin of human volunteers following different application times with a test material bathing system.
- Trial name
- NCT04235985
- Testing
- Chlorhexidine Gluconate with HUBS
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Molnlycke Health Care AB
Cardiopulmonary Resuscitation, Cardiopulmonary Arrest
Evaluation of Efficacy of Online Real-time Home CPR Training Program
The purpose of this study is to evaluate the effectiveness of a real-time home CPR(cardiopulmonary resuscitation) training program. The study participants will be allocated to two different CPR training programs.
- Conditions
- Cardiopulmonary Resuscitation, Cardiopulmonary Arrest, Education
- Trial name
- NCT05023616
- Testing
- Real-time home CPR training, Conventional CPR training
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Depressive Disorder and Anxiety Disorders
First Study in Humans With GSK206136
This is the first study in humans with GSK206136 to evaluate what effects: good or bad, the drug has on human health (safety and tolerability) and the amount of drug which gets into the bloodstream and is eliminated from the body…
- Trial name
- NSB101909 (NCT01059578)
- Testing
- GSK206136, PET
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Study to Evaluate Safety, Tolerability and Pharmacokinetics (PK) (Including Food Effect) of Oral Doses of AZD5847 in Healthy Volunteers
The main purpose of this study is to assess the safety and tolerability of AZD5847 after receiving oral doses on a single day (Part A) or after receiving a single oral dose in two periods (Part B).
- Trial name
- NCT01037725
- Testing
- AZD5847
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Ligament; Laxity
Evaluation of Anterior Tibial Translation of the Knee in Healthy Women, at Two Times of the Menstrual Cycle, on Hormonal Contraceptives or Not (FLEX)
Women's participation in sports at all levels has been increasing in recent decades. Many individual and team sports are at risk of anterior cruciate ligament (ACL) injury.
- Trial name
- FLEX (NCT05177549)
- Testing
- Bilateral knee examination with Lachmeter®
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Laryngoscopy
The Rate of Successful Intubation and the Required Time for Intubation, Using Vie Scope and Macintosh Laryngoscope Will be Compared, in Order to Evaluate the Efficacy of Vie Scope in Comparison With Macintosh in Expected Easy Airways.
The rate of successful intubation and the required time for intubation, using Vie Scope and Macintosh Laryngoscope will be compared, in order to evaluate the efficacy of Vie Scope in comparison with Macintosh in expected easy…
- Trial name
- NCT06149338
- Testing
- Macintosh laryngoscope, Vie Scope
- Where
- Greece
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- St. Andrew's General Hospital, Patras, Greece