Clinical trials: Invitro Fertilization
Infertility
Endometrial Injury and IVF-ET Outcome
Implantation of the human embryo is the limiting factor in the success of invitro-fertilization and embryo transfer(IVF-ET).We wanted to find out whether creating a local injury to the endometrium in the non-transfer cycle would…
- Trial name
- NCT00796341
- Testing
- PIPELLE ENDOMETRIAL SAMPLING
- Where
- India
- Volunteers
- 99 people
- Sponsor
- Bangalore Assisted Conception Centre
IVF
Uterine Lesions and Their Association to Invitro Fertilization(IVF) or Intracytoplasmic Sperm Injection(ICSI) Outcome
1. To study the effect of uterine wall , intracavitary , cervical as well as cervical canal lesion on the outcome of IVF/ICSI cycle. 2. To establish a score for prediction of IVF/ICSI cycle success .
- Trial name
- NCT04939376
- Testing
- IVF
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility, Invitro Fertilization
Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure
Women with history of previous IVF cycle failure will be subjected to a fresh IVF cycle. At the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will…
- Trial name
- NCT02329197
- Testing
- Human Chorionic Gonadotropin (HCG)
- Where
- Egypt
- Volunteers
- 380 people
- Sponsor
- Mansoura University
Invitro Fertilization
Embryoscope and Reproductive Outcome
cases with embyos cultured in the standard incubator and evaluated only by morphology are compared to cases with embryos continuously monitored by the embryoscope followed by embryo selection based on a multivariable model
- Trial name
- NCT02764255
- Volunteers
- 770 people
- Sponsor
- Ahmed Maged
Mullerian Anomaly of Uterus, Nec
Congenital Uterine Anomalies & Pregnancy in Polycystic Ovarian Syndrome
Prospective research in which patients who applied to UUTF Gynecology and Obstetrics ART center for the treatment of infertility (inability to conceive despite one year of unprotected sexual intercourse), who will undergo IVF due…
- Trial name
- CONUTA&PPCOS (NCT04776915)
- Testing
- Ultrasound and Hysterosalpingography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uludag University
Infertility, Female
Transvaginal Ultrasonography Guided Embryo Transfer
to evaluate the value of using transvaginal ultrasound guided embryo transfer in obese patients undergoing in vitro fertilization.
- Trial name
- NCT03473028
- Testing
- transabdominal ultrasound guided embryo transfer, transvaginal ultrasound guided embryo transfer
- Where
- Egypt
- Volunteers
- 800 people
- Sponsor
- Kasr El Aini Hospital
Ovarian Aging, In Vitro Fertilisation (IVF) Treatment
Follicular Fluid microRNAs in Ovarian Aging and Reproduction
The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes.
- Conditions
- Ovarian Aging, In Vitro Fertilisation (IVF) Treatment, InVitro Fertilization, In Vitro Fertilization Outcome
- Trial name
- NCT07214246
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Central Florida
Female Infertility Due to Diminished Ovarian Reserve
Antagonist Protocol in Poor Responders
The effect of use of the growth hormone with antagonist protocol on the outcome of the IVF/ICSI cycles in poor responders.
- Trial name
- NCT02195947
- Testing
- Growth Hormone
- Where
- Egypt
- Volunteers
- 141 people
- Sponsor
- Cairo University
Invitro Fertilization
Factors Associated With Pregnancy Loss in IVF Women
Maternal and clinical characteristics associated with spontaneous second-trimester pregnancy loss (between 12 1/7 and 23 6/7 weeks of gestation) will be assessed.
- Trial name
- NCT02383394
- Testing
- follow up antenatal care
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Infertility
Management of Abnormally Fertilized Zygotes? InVitro Correction of 3PN
In this newly developed protocol, and idea, is to manage those abnormally developed zygotes from different ART procedures. The investigators developed the plan and requirements needed to select the target extra nucleus or…
- Trial name
- NCT02358759
- Testing
- Correction of abnormally fertilized oocytes
- Where
- 2 sites in Bahrain, Egypt
- Volunteers
- 22 people
- Sponsor
- Ahmad Mustafa Mohamed Metwalley
Invitro Fertilization
Value of Cabergoline and Low Dose Aspirin in Poor Responders Undergoing ICSI-ET With GnRH Agonist Flare-Up-Protocol
Ovarian stimulation will be done using the Microdose flare-up regimen. The patient will receive diluted doses of the GnRH agonist leuprolide acetate 40 µg, given subcutaneously twice daily.
- Trial name
- NCT03263299
- Testing
- cabergoline, Aspirin, GnRH agonist
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Infertility
Intralipid Therapy for Women 35-40 Years With Positive Natural Killer Cells Undergoing Intracytoplasmic Sperm Injection (ICSI)
Intralipid can suppress natural killer cells that are known to be involve in repeated implantation failure and recurrent miscarriages.Intralipid is made of purified soybean oil, egg phospholipids, glycerol and water.
- Trial name
- NCT01916798
- Testing
- Intralipid infusion
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Invitro Fertilization
Comparative Study Between ICSI Results in Transvaginal Ultrasound Guided Embryo Transfer and Transabdominal Ultrasound Guided Embryo Transfer
This prospective study will be conducted on 120 patients candidates for ICSI cycle and following the long protocol for controlled ovarian stimulation; the patients were randomly allocated in a 1:1 ratio to either group A; where…
- Trial name
- NCT03683043
- Testing
- Long GnRH agonist protocol, Embryo transfer
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Infertility
Delayed Embryo Transfer in Poor Responders
Poor ovarian response indicates inadequate ovarian response to ovarian stimulation. In the current study the investigators will attempt to compare antagonist and short protocols regarding oocyte as well as embryo quantity and…
- Trial name
- NCT02431689
- Testing
- IVF/ICSI
- Where
- 3 sites in Egypt
- Volunteers
- 400 people
- Sponsor
- Cairo University
InVitro Fertilization
Telomeres and Reproduction in Women
The purpose of the study is to describe the relationship between leukocyte, granulose cell and polar body telomere length, telomere injury foci (TIFs), polarized light microscopy of oocyte spindles and their frequency in the eggs…
- Trial name
- NCT01576991
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Invitro Fertilization
Endometrial Injury and Implantation Rates Before First ICSI Cycle
Midluteal single endometrial strip will be taken using a Novak curett under general anasthesia to avoid discomfort and cramping and to proceed to cervical dilatation in case of forbidden cervix, the step that will be beneficial…
- Trial name
- NCT02660125
- Testing
- Endometrial scratch injury
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
WHITE NOISE, INVITRO FERTILIZATION, PAIN, ANXIETY, COMFORT
White Noise and In-vitro Fertilizasyon
In vitro fertilization is the placement of embryos into the uterus with a catheter under ultrasound guidance after the fertilization of sperm and oocytes in a laboratory tube.
- Trial name
- NCT06996340
- Testing
- White noise group, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Yasemin Sökmen
Ovarian Hyperstimulation Syndrome
Preventive Application of Letrozole Decrease Incidence of Early Onset of OHSS
Letrozole is one kind of aromatase inhibitors which may have effect on decrease estrogen in luteal phase and inhibit the luteal function of ovary.
- Trial name
- NCT02670304
- Testing
- letrozole, Aspirin
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
InVitro Fertilization, Gonadotropins
rFSH vs rFSH+rLH in Dydrogesterone-Based Progestin Protocol: A Prospective Study
This study aims to compare two commonly used hormone treatments for women undergoing IVF. All participants will receive a stimulation protocol that includes dydrogesterone, a medication used to safely control natural hormone…
- Trial name
- DYG-GONA (NCT07348757)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Invitro Fertilization
Long Protocol and Freeze All Embryos vs Antagonist Protocol With Fresh Embryo Transfer in PCOS Patients Undergoing ICSI
Patients will be divided into two groups Group A; patients using long protocol and freeze all embryos Group B; patients using antagonist protocol with fresh embryo transfer Patients will be carefully chosen according to a strict…
- Trial name
- NCT03118830
- Testing
- Triptorelin, cetrorelix, Recombinant Follicle Stimulating Hormone
- Where
- Egypt
- Volunteers
- 204 people
- Sponsor
- Cairo University