Clinical trials: Involutional Osteoporosis
Osteoporosis
A Study for the Transdermal Application of Teriparatide
The primary purpose of this study is to help answer the following research questions: 1. How teriparatide given using a skin patch (transferred through the skin using the ViaDerm Teriparatide System) compares to teriparatide…
- Trial name
- NCT01011556
- Testing
- Subcutaneous Teriparatide, Transdermal Teriparatide
- Where
- 18 sites in Argentina, Estonia and 3 more
- Volunteers
- 233 people
- Sponsor
- Eli Lilly and Company
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Age-Related Osteoporosis
Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover
Osteoporosis affects 24.5% of women over 65 and results in fracture-related hospital admissions exceeding those of heart attacks, strokes and breast cancer combined.
- Trial name
- NCT05151484
- Testing
- Teriparatide, Alendronate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Madhumathi Rao
Osteoporosis, Osteoporosis (Senile)
Epidemiological Study of Osteoporosis in the Elderly Population of Shandong Province
At present, there is little epidemiological information on osteoporosis in the elderly population of Shandong Province, especially the lack of systematic research on the role of bone metabolism and biochemical indicators in the…
- Trial name
- NCT06915935
- Testing
- dualenergy X-ray absorptiometry
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
Osteoporosis (Senile)
Contribution of Recreational Exercises to Balance and Muscle Strength in Osteoporosis Risk
This study aims to evaluate the effects of recreational exercises such as Pilates, swimming and walking on muscle strength and balance in women at risk of osteoporosis.
- Trial name
- NCT07245355
- Testing
- Experimental Group 1, Experimental Group 2, Experimental Group 3
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Suleyman Demirel University
Osteoporosis, Osteoporosis, Age-Related
Safety and Efficacy of Abaloparatide-SC in Men With Osteoporosis (ATOM)
A 12-month study to measure the efficacy and safety of abaloparatide in men with osteoporosis.
- Conditions
- Osteoporosis, Osteoporosis, Age-Related, Osteoporosis Localized to Spine, Age Related Osteoporosis
- Trial name
- NCT03512262
- Testing
- Abaloparatide
- Where
- 34 sites in United States, Italy and 1 more
- Volunteers
- 228 people
- Sponsor
- Radius Health, Inc.
Osteoporosis Senile, Obesity, Visceral
Anthropometric And Body Composition Measurements Related To Osteoporosis In Geriatric Population
The patients who consulted to the geriatric outpatient clinic between 2018 and 2019 were included in the study. The inclusion criterions were being at or over the age of 65 and diagnosed with osteoporosis according to WHO…
- Trial name
- NCT04255173
- Testing
- Body mass index, waist circumference, hip circumference
- Where
- Turkey (Türkiye)
- Volunteers
- 571 people
- Sponsor
- Istanbul Medeniyet University
Senile Osteoporosis With Current Pathological Fracture Lower Leg (Diagnosis)
Rare Variation and Remote Gene Regulation of Osteoporosis Related Phenotypes in Han Chinesse
Bone density is recognized as the most important factor to measure osteoporosis, and the prevalence of osteoporosis increases with age.
- Trial name
- NCT04129671
- Testing
- No intervention was applied
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Age Related Osteoporosis, Fall
Effects of FRAX+SARC-F Pre-screening on Preventing Fragility Fracture and Fall in Community-dwelling Older Adults
Hip fragility fractures are a major threat to functional independence in older adults locally and globally. In Hong Kong, the prevalence of osteoporosis and osteopenia in people aged >50 years were reported to be as high as 37%…
- Trial name
- NCT04709393
- Testing
- FRAX+SARC-F questionnaire pre-screening
- Where
- Hong Kong
- Volunteers
- 2,956 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Osteoporosis Postmenopausal
Efficacy and Safety of Odanacatib (MK-0822) in Participants With Involutional Osteoporosis (MK-0822-022)
The purpose of this study is to assess the dose-response on the percent change from baseline in lumbar spine bone mineral density (BMD) at lumbar vertebrae 1 to 4 (L1- L4) when odanacatib (MK-0822) 10 mg, 25 mg, 50 mg or placebo…
- Trial name
- NCT00620113
- Testing
- Odanacatib, Vitamin D3, Calcium carbonate
- Volunteers
- 287 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoarthritis, Osteoarthritis (OA) of the Knee
A Clinical Study Evaluating the Dermal Safety of Soluble Denosumab Microneedle Patches
The goal of this clinical trial is to evaluate the skin safety of a soluble denosumab microneedle patch in participants with osteoporosis and osteoarthritis.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoporosis, Osteoporosis (Senile)
- Trial name
- CSEDSSDMP (NCT07085520)
- Testing
- Microneedle with 0.24mg Denosumab, Saline Microneedle Patch, Microneedle with 1.2mg Denosumab
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Bone Diseases, Metabolic, Depression, Involutional
Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression
In this study researchers would like to learn more about the low levels of bone mineral density seen in approximately half of women in their forties diagnosed as currently having or previously had depression.
- Conditions
- Bone Diseases, Metabolic, Depression, Involutional, Osteoporosis
- Trial name
- NCT00001916
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Involutional Osteoporosis
Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan
The purpose of this study is to evaluate the efficacy and safety of ONO-5920 in patients with involutional osteoporosis.
- Trial name
- NCT00212628
- Testing
- Minodronic acid hydrate
- Where
- 9 sites in Japan
- Volunteers
- 444 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Involutional Osteoporosis
Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan
The purpose of this study is to evaluate the efficacy and safety of ONO-5920 in patients with involutional osteoporosis.
- Trial name
- NCT00212719
- Testing
- ONO-5920
- Volunteers
- 250 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Involutional Osteoporosis
Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan
The purpose of this study is to evaluate the efficacy and safety of ONO-5920 in patients with involutional osteoporosis.
- Trial name
- NCT00212667
- Testing
- ONO-5920
- Volunteers
- 650 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Osteoporosis, Osteopenia
Models of Primary Osteoporosis Screening in Male Veterans
Models of Osteoporosis Screening in Male Veterans aims to test 1 distinct care model of primary osteoporosis screening in men within the VA healthcare setting.
- Conditions
- Osteoporosis, Osteopenia, Osteoporotic Fracture
- Trial name
- MOPS (NCT04079868)
- Testing
- Bone Health Service Model
- Where
- 3 sites in United States
- Volunteers
- 3,512 people
- Sponsor
- VA Office of Research and Development
Age-Related Osteoporosis
Training in a Local Community Aimed Upon Musculoskeletal Health Promotion for Postmenopausal Women
To minimize fracture risk, diverse and varied training of high intensity (multimodal training) is recommended to increase bone strength.
- Trial name
- NCT05164679
- Testing
- multimodal training (MMT)
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy, Involutional Depression
Bone Mineral Density in Women With Major Depression
The purpose of this study is to examine calcium absorption and bone mineral density in women with depression. Research indicates that pre-menopausal women with depression have significantly lower bone mineral density (BMD) than…
- Conditions
- Healthy, Involutional Depression, Osteoporosis
- Trial name
- NCT00001413
- Where
- United States
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Osteoporosis, Postmenopausal, Osteoporosis
Early Effects of Abaloparatide on Tissue-Based Indices of Bone Formation and Resorption
The objective of this study is to measure the early effects of abaloparatide on tissue-based bone formation using samples obtained by transiliac crest bone biopsy after quadruple fluorochrome labeling.
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis, Osteoporosis Vertebral, Osteoporosis Risk
- Trial name
- NCT03710889
- Testing
- Abaloparatide
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Radius Health, Inc.