Clinical trials: Iodine Deficiency
Hypothyroidism, Pregnancy Related
Normal Range of TSH and FT4 in Pregnancy
Physiological changes necessitate the use of pregnancy-specific reference ranges for thyrotrophin (TSH) and free T4 (FT4) to diagnose thyroid dysfunction during pregnancy.
- Conditions
- Hypothyroidism, Pregnancy Related, Thyroid, Dysfunction
- Trial name
- NRTSHTURKEY (NCT04860622)
- Testing
- Serum thyroid function tests
- Where
- Turkey (Türkiye)
- Volunteers
- 528 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Iodine Deficiency, Nutritional Requirements
An Iodine Balance Experiment
A 4-week study was conducted in 25 Chinese euthyroid women. Unified diets with different iodine contents (cooked with non-iodized salt or iodized salt) were provided in two different periods.
- Trial name
- NCT03279315
- Testing
- iodized table salt, non-iodized table salt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Iodine Deficiency, Thyroid
Iodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho Region
Full intellectual capabilities are achieved only if crucial nutrients are present during development. Iodine deficiency is the most common cause of preventable brain harm in infants.
- Conditions
- Iodine Deficiency, Thyroid, Pregnancy Related, Psychomotor Impairment
- Trial name
- IodineMinho (NCT04288531)
- Testing
- Iodine supplementation
- Where
- 10 sites in Portugal
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Minho
Recurrent Goiter
Thyroid Lobectomy With or Without Levothyroxine Treatment Postoperatively
The aim of this study was to compare the prevalence of recurrent nodular goiter in the contralateral thyroid lobe among patients after unilateral thyroid lobectomy for unilateral multinodular goiter receiving versus not receiving…
- Trial name
- NCT00941551
- Testing
- levothyroxine, no levothyroxine
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Jagiellonian University
Iodine Deficiency
Comparison of I-FFQ and Two Reference Methods
Mild-to-moderate iodine deficiency remains a problem in many parts of the world, including Norway. Of particular concern are fertile, pregnant, and lactating women.
- Trial name
- NCT05934006
- Testing
- spot urine samples
- Where
- Norway
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Iodine Deficiency
Variability of Daily Iodine Intake: The Effects of Intra- and Inter-individual Variability in Iodine Nutrition Studies
Iodine status in populations is assessed using urinary iodine concentration (UIC) measured in spot urine samples. The iodine intake is classified as deficient, sufficient, or excessive iodine based on the median UIC (mUIC).
- Trial name
- VIOLET (NCT03731312)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Folate Deficiency, Iodine Deficiency
Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid
The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status.
- Conditions
- Folate Deficiency, Iodine Deficiency, Anemia Macrocytic, Anemia Deficiency
- Trial name
- DFS-IoFA-2 (NCT06223854)
- Testing
- Iodized salt, Experimental: Iodized salt with lower-dose folic acid fortification, Experimental: Iodized salt with higher-dose folic acid fortification
- Where
- Ethiopia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Iodine Deficiency
Prevalence of Iodine Deficiency in Remote Communities of Haiti
Haiti is one of the few remaining countries that is at risk of iodine deficiency disorders. In the 2018 survey, iodized salt was found in <20% of households and iodine excretion from non-pregnant and pregnant women suggested…
- Trial name
- NCT05275452
- Testing
- No intervention
- Where
- Haiti
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine Deficiency
Nutrition & Food Choices in Early Pregnancy
PICk study is a mHealth intervention in women trying to conceive and women up to 14 weeks pregnant, aiming to guide food choices, to achieve the recommended iodine intake through diet.
- Trial name
- PICk (NCT05685056)
- Testing
- Text messages
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Iodine Deficiency, Nutrition Poor
Effects of Maternal Multiple Micronutrient Supplementation During Lactation on Child Development in Ethiopia
The goal of this clinical trial is to learn about the effects of iodine-containing multiple micronutrient supplements provided to breastfeeding mothers who live in settings with mild iodine deficiency.
- Conditions
- Iodine Deficiency, Nutrition Poor, Development, Infant, Breastfeeding
- Trial name
- EMECHAT (NCT05901766)
- Testing
- UNIMMAP Multiple Micronutrient Supplement
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Brown University
Dietary Intervention, Pregnancy Jail
Group Education to Improve the Iodine Nutrition in Pregnancy: Cluster Randomized Trial
The purpose of this study is to assess the effectiveness of individual education versus group education about dietary habits and iodine supplementation to decrease iodine deficiency in pregnant women
- Conditions
- Dietary Intervention, Pregnancy Jail, Iodine Deficiency
- Trial name
- NCT01301768
- Testing
- Group Education
- Where
- Spain
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Iodine Deficiency, Pregnancy Related
Assessment of Dried Blood Spot Thyroglobulin and Urinary Iodine Concentration in Pregnant Women
To avoid iodine deficiency and its consequences in pregnant women and their offspring, women should reach a sufficient iodine intake long before conception.
- Trial name
- STRIPE (NCT03176706)
- Testing
- no intervention
- Where
- New Zealand
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Folate Deficiency, Neural Tube Defects
Folic Acid Salt Study (FISFA Zambia)
Question: How effective is fortified iodized salt with folic acid (FISFA) in increasing serum and red blood cell folate in non-lactating, non-pregnant women of reproductive age in the country of Zambia who do not have active food…
- Trial name
- NCT06734611
- Testing
- Fortified Iodized Salt with Folic Acid (FISFA)
- Where
- 2 sites in United States, Zambia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Vitamin D Deficiency, Iodine Deficiency
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.
Vitamin D deficiency is common worldwide, including in infants and children, and rickets remains a public health concern in many developing countries.
- Conditions
- Vitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
- Trial name
- Haiti (NCT02301520)
- Where
- 2 sites in Haiti
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Iodine Deficiency
The Bioavailability of Iodine in Plant-based Milk Alternatives
Iodine is a mineral commonly found in seafood and dairy products such as milk and cheese. Iodine is important as it is required to make thyroid hormones which regulate growth and metabolism at all stages of life.
- Trial name
- IoBIO (NCT06775795)
- Testing
- Oat milk, Soya milk, Cow's milk
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Congenital Hypothyroidism, Pregnancy
Iodine Status in Pregnant Women and Their Newborns: is Congenital Hypothyroidism Related to Iodine Deficiency in Pregnancy?
Iodine is an essential component of thyroid hormone, which is necessary for many metabolic processes as well as the maturation of the CNS. Deficiencies of iodine have deleterious effects on both pregnant women and infants.
- Conditions
- Congenital Hypothyroidism, Pregnancy, Iodine Deficiency
- Trial name
- NCT00505479
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Zhejiang University
Iodine Deficiency
Caribbean Island Urinary Iodine Survey 2018
Many of the Caribbean island nations have no data on iodine status in their populations. Iodine deficiency in children can reduce IQ but can be easily corrected through a program of salt iodization.
- Trial name
- CRUISE (NCT04388540)
- Where
- 10 sites in Antigua and Barbuda, Barbados and 8 more
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iodine-Deficiency; Hypothyroidism
Iodine Status in Pregnant Women in Israel
Worldwide Data suggest that Iodine deficiency is a concern among healthy pregnant women. Thus, screening first trimester healthy pregnant women for iodine status is of clinical value for mother and child as iodine deficiency…
- Trial name
- NCT03120221
- Testing
- Urine sample for iodine measurement
- Where
- 2 sites in Israel
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Iodine Deficiency
Iodine Status After Intake of Sushi and Seaweed Salad
Seaweed is becoming increasingly popular in the Western part of the world, especially sushi wrapped in nori and seaweed salad, also called wakame.
- Trial name
- NCT05773456
- Testing
- Sushi and wakame salad
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Iron Deficiency (ID), General Anemia
Community Interventions to Improve Iron and Iodine Status in Mother and Child Dyads in Northern Ghana
BACKGROUND Ghana has reduced food insecurity prevalence by 49.2% in two decades. However, prevalence of malnutrition especially stunting (in <children5yr) has not matched the changes in food security levels.
- Conditions
- Iron Deficiency (ID), General Anemia, Iron Deficiency Anemia (IDA)
- Trial name
- NCT03754998
- Testing
- Intervention Group
- Where
- Ghana
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Michigan State University