Clinical trials: Iohexol
Acute Kidney Injury, Critically Ill Children
Iohexol for Measuring Renal Function
Approximately 25-35% of all children admitted to the paediatric intensive care unit (PICU) or neonatal intensive care unit (NICU) will develop Acute Kidney Injury (AKI) during the first seven days after admission.
- Trial name
- HERO (NCT03946345)
- Testing
- Iohexol Inj 300 MG/ML
- Where
- Netherlands
- Volunteers
- 105 people
- Sponsor
- Radboud University Medical Center
Carnitine Ingestion
Measurement of Renal Function With Iohexol in Subjects Ingesting Carnitine
The investigators will measure renal function in subjects ingesting carnitine to determine if the product alters renal function.
- Trial name
- NCT01392313
- Testing
- Carnitine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Chronic Kidney Diseases
ProtocoL for GFR Measurement Using Iohexol (SCOPE-PLUS) - A Substudy of the SCOPE Study
SCOPE-PLUS is an optional substudy of the observational SCOPE Study (Screening for Chronic Kidney Disease among Older People across Europe, NCT02691546).
- Trial name
- SCOPE-PLUS (NCT04449172)
- Where
- 5 sites in Austria, Italy and 2 more
- Volunteers
- 100 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Acute Kidney Injury, Chronic Kidney Insufficiency
Comparison of Two Different External Clearance Markers - Mannitol and Iohexol for Measuring Glomerular Filtration Rate
GFR is the best parameter of the real kidney function. Measurements, however are time-consuming and have limited capacity. Patients treated in the intensive care units often have more than one organ-insufficiency and acute kidney…
- Trial name
- GFR (NCT06238310)
- Testing
- Comparison of two external marker substance for measuring glomerular filtration rate
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Katalin Kiss
Renal Disease, Renal Insufficiency
Two-Point Measurement of Glomerular Filtration Rate by Iohexol Plasma Disappearance
The purpose of this study is to measure glomerular filtration rate (GFR) by iohexol plasma disappearance (gold standard) and measure serum Cystatin C levels (surrogate marker) in patients enrolled in our prospective study at…
- Trial name
- NCT01545531
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Washington
Pain
Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block
As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block.
- Trial name
- NCT07174440
- Testing
- Ropivacaine (Epidural analgesia), Dexmedetomidine, Iohexol
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University Hospitals Cleveland Medical Center
Augmented Renal Clearance, Critically Ill
Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance
Evaluation of glomerular filtration rate using iohexol plasma clearance in critically ill patients with augmented renal creatinine clearance
- Trial name
- GFR-ARC (NCT04776486)
- Testing
- Iohexol
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity
Effect of VI-0521 (Qsymia®) on Glomerular Filtration Rate (GFR) in Overweight or Obese Healthy Subjects
The main purpose of this study is measure the effect of VI-0521 on kidney function. Specifically, glomerular filtration rate (GFR) will be measured at baseline, after 4 weeks of study treatment, and after an additional 4 weeks of…
- Trial name
- NCT02229214
- Testing
- Qsymia
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Colorectal Cancer
Virtual Colonoscopy Using Omnipaque as a Contrast Agent
CT colonography (CTC) is a validated screening exam for colorectal cancer. The diagnostic accuracy of CTC depends on the quality of the bowel cleansing and contrast tagging of residual stool and fluid.
- Trial name
- NCT04582500
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Chronic Kidney Disease (Stages 4 and 5), Chronic Kidney Disease 5D
The Practicality and Utility of Measured vs Estimated GFR in adCKD
The goal of this observational study is to assess if new ways of measuring kidney function can better predict when individuals will become symptomatic due to kidney failure, and whether residual kidney function can be accurately…
- Trial name
- NCT07450534
- Testing
- Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Manchester University NHS Foundation Trust
Rectal Cancer, Colon Cancer
Measurement of Perioperative Glomerular Filtration Rate
Our objective is to monitor glomerular filtration rate (GFR)during the perioperative phase of patients undergoing robotic surgery for rectum or large bowel cancers.
- Trial name
- NCT03881332
- Where
- Norway
- Volunteers
- 4 people
- Sponsor
- University Hospital of North Norway
Kidney Diseases, Kidney Injury
Study of MB-102 (Relmapirazin) and the Use of the MediBeacon® Transdermal GFR Measurement System Using the TGFR Reusable Sensor With Disposable Adhesive Ring
The goal of this clinical trial was to compare transdermal glomerular filtration rate (tGFR) to plasma-derived indexed GFR (nGFR) using MB-102 (relmapirazin) as the fluorescent compound.
- Conditions
- Kidney Diseases, Kidney Injury, Kidney Failure
- Trial name
- NCT05777174
- Testing
- MB-102, MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)
- Where
- 5 sites in United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Iohexol, Pharmacokinetics
Renal Function Assessment in Critically Ill Children
Identification of renal dysfunction in critically ill children is often delayed due to lack of accurate methods for evaluation of glomerular filtration rate (GFR).
- Conditions
- Iohexol, Pharmacokinetics, Renal Function, Critically Ill Children
- Trial name
- IOHEXOL (NCT05179564)
- Testing
- iohexol administration, iohexol blood sampling
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Chronic Kidney Disease, Renal Insufficiency
Comparison of Markers of Kidney Function
Glomerular filtration rate (GFR) is the best known measurement of kidney function. Serum creatinine (blood test) is the most commonly used marker to predict GFR.
- Trial name
- NCT01403766
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Acute Renal Failure
Measurement of Iohexol Plasma Clearance in Patients Leaving ICU After Acute Renal Failure
IOXSOR study's purpose to determine the frequency of non resolutive renal failure (estimated by the clearance of iohexol) at end of stay in ICU patients who have had acute renal failure episode.
- Trial name
- IOXSOR (NCT02961478)
- Testing
- IOHEXOL
- Where
- 11 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Healthy
Effect of Repeated Doses of BI 1060469 and BI 1021958 on Glomerular Filtration Rate (GFR) in Healthy Volunteers
Main objective is to investigate the measured glomerular filtration rate (mGFR) as assessed by iohexol clearance in healthy male normovolemic subjects after oral administration of single and repeated doses of BI 1060469, and BI…
- Trial name
- NCT02202512
- Testing
- Cimetidine, BI 1060469 high dose, BI 1060469 low dose
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Subjects Referred to CT-examination of the Abdomen
A Randomized, Controlled Trial to Evaluate CT Image Quality Lumentin® 44
Subjects referred for abdominal or thoracoabdominal CT-examination will be randomised to either the three contrast agents Lumentin® 44, Omnipaque® or Movprep.
- Trial name
- NCT03326518
- Testing
- Lumentin® 44, Diluted Omnipaque®, Movprep®
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Lument AB
HIV
Measurement of Glomerular Filtration Rate (GFR) in HIV Patients: Single-center Study Comparing the Accuracy of Estimators of GFR Versus Iohexol Plasma Clearance
Cystatin C, a protease inhibitor produced by most nucleated cells, is freely filtered by the kidneys, and its plasma assay reflects the GFR.
- Trial name
- HIVOL (NCT02522338)
- Testing
- iohexol
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hypothyroidism
Pediatric Risk of Hypothyroidism With Iodinated Contrast Media
This is a Phase 4 multicenter prospective study to estimate the proportion of patients aged birth to 3 years who develop hypothyroidism within 6 months after receiving intravascular iohexol (Omnipaque™), iodixanol (Visipaque™)…
- Trial name
- NCT03631771
- Testing
- Iohexol, Iodixanol, Iopromide
- Sponsor
- GE Healthcare
Healthy
Omnipaque Versus Gastroview as Oral Contrast for Abdominal and Pelvic CT
Patients who are scheduled by their health care provider for routine computed tomography (CT) scan will be asked to participate in this study.
- Trial name
- NCT00478556
- Testing
- Omnipaque, Gastroview
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham