Clinical trials: Iron
Anemia in Pregnancy, Preeclampsia
A Retrospective Analysis of Neevo®/Neevo®DHA Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
This study is a multi-site, retrospective chart review to determine the effect of Neevo® or Neevo®DHA (with higher folate and B12) versus standard prenatal vitamins on hemoglobin (Hgb) levels in pregnant women throughout the…
- Trial name
- NCT01062958
- Testing
- Neevo® (a medical food), Prenatal vitamins (≤1mg folic acid, 27 - 35mg iron, and ≤12mcg vitamin B12)
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
Overweight, Nutritional Deficiency
The PROTEIN Project
New advances in information computer technology and artificial intelligence (AI) offer the possibility to create a personalized tool and support system for healthy living and eating, and this is the principal objective of the…
- Conditions
- Overweight, Nutritional Deficiency, Poor Nutrition, Iron-deficiency
- Trial name
- PROTEIN (NCT04829851)
- Testing
- PROTEIN Mobile App, Expert Dashboard
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Neural Tube Defects, Folic Acid Deficiency
Using Iodized Salt to Improve Serum Folate, B12 and Iron Levels
Question: How effective is fortified iodized salt in increasing serum concentrations of folate, B12 and iron among non-pregnant and non-lactating women of reproductive age? Hypothesis: Micronutrient fortified iodized salt can…
- Conditions
- Neural Tube Defects, Folic Acid Deficiency, Spina Bifida, Anencephaly-Spina Bifida
- Trial name
- NCT06904612
- Testing
- Micronutrient fortified iodized salt
- Where
- 2 sites in United States, India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hydrocephalus and Neuroscience Institute
Iron Deficiency Anemia
Total Dose Infusion of Ferumoxytol(1020mg) in 15 Minutes for Iron Deficiency Anemia
The aim of the study is to recruit 30 patients who have been referred to Auerach Hematology Oncology Assoc. for the treatment of iron defeciency anemia with iv iron (Ferumoxytol 1020 mg) administered via infusion pump over 15…
- Trial name
- NCT01374919
- Testing
- ferumoxytol
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Auerbach Hematology Oncology Associates P C
Huntington Disease
Clinicopathological MRI and CSF Correlates in Huntington's Disease.
In this study the investigators will link brain iron levels obtained from quantitative susceptibility maps of HD patients with specific and well-known clinical CSF markers for iron accumulation, neurodegeneration and…
- Trial name
- NCT05534139
- Testing
- 7T MRI-scan, CSF collection via lumbar puncture, Blood withdrawal
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Iron Deficiency Anemia
Effect of Rice Fortification With Iron on Anemia Among Children
This was a double-blind community-based trial, placebo controlled. During 16 weeks, children in the intervention group (GI, n=180) received iron fortified rice, and children in the control group (GC, n=174) received rice with…
- Trial name
- NCT00727545
- Testing
- iron bisglycine chelate
- Where
- Brazil
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Focus of Study: 1- Effect of Tea Consumption on Gut Microbiota, Focus of Study: 2- Effect of Tea Consumption on Body-iron Status
Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status
Iron is an essential micronutrient for nearly all living organisms, including microbes. The adult human body contains approximately 3-5 g of iron (45-55 mg/kg of body weight in adult women and men, respectively).
- Trial name
- NCT05019573
- Testing
- Black tea
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Episodic Migraine, Chronic Daily Migraine
fMRI of the Brainstem in Migraine Sufferers and Controls. Does Iron Deposition Correlate With Progression of Disease?
This is a 2 visit research study for patients with or without a diagnosis of migraine. Participants will be administered informed consent, have a medical history taken and a physical examination performed, and complete 3…
- Trial name
- NCT00868556
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Melanoma
Sentinel Lymph Node Mapping Using Magtrace and MRI in Healthy Subjects for Potential Use in Melanoma Patients
Sentinel lymph node biopsy (SLNB) is crucial in the management of malignant melanoma treatment and is currently performed by pre-operatively inject a colloid nanomaterial labeled with Technetium (99mTc) as radioactive tracer.
- Trial name
- TRACIE (NCT05054062)
- Testing
- Sentinel node mapping using MRI
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Iron Deficiency (Without Anemia)
Absorption of Iron From Stabilized Lactoferrin: A Study in Women With Iron Deficiency
Lactoferrin (LF) is a natural iron-binding protein found in milk. It exists either in an iron-free state (apo-LF) or bound to iron (holo-LF).
- Trial name
- LOBSTER (NCT07394972)
- Testing
- FeSO4 + meal-matrix, FeSO4 + native LF + meal-matrix, FeSO4 + NaCas-LF + meal-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nicole Stoffel
Anemia, Nutritional Deficiency
Anemia in Older Adults
A cross-sectional study with 829 older Mexican adults were recruited from July to September 2015, from four localities in the southern region of México.
- Conditions
- Anemia, Nutritional Deficiency, Inflammation
- Trial name
- NCT04820465
- Testing
- Non available due to cross-sectional study design
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Cognitive Ability, General
Nutrigenomics, PUFA, Iron and Cognition Amongst Under-two-year-old Indonesian Children
Rationale: Review on the positive effect of long chain polyunsaturated fatty acids (LCPUFA), especially docosahexanoic acid (DHA), supplementation on cognitive function in human using randomized controlled trials (RCTs) showed…
- Trial name
- NUPICO (NCT01504633)
- Testing
- DHA/EPA and iron supplementation
- Where
- Indonesia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pregnancy
Néevo®/NéevoDHA® P.L.U.S. Program (Progress Through Learning, Understand & Support)
This is an observational study in which patients who have been prescribed Néevo®/NéevoDHA® are invited to participate in surveys about their pregnancy and experiences with Néevo®/NéevoDHA®.
- Trial name
- NCT01358552
- Testing
- Néevo®/ NéevoDHA®
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.
Infant Development
Early Iron Exposure on the Gut Microbiota in Young Infants
This study will look at the amount of iron in infant formula and how that affects a child's gut development. The children of mothers who plan to formula feed their children will be randomized to receive either high iron or low…
- Trial name
- IF (NCT03828708)
- Testing
- Iron in infant formula
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sickle Cell Disease, Thalassemia
Multi-Center Study of Iron Overload: Pilot Study
The purpose of this study is to initiate pilot studies to demonstrate that a sufficient number of iron-overloaded thalassemia, SCD and DBA populations with similar duration of chronic transfusion, and age at start of transfusions…
- Conditions
- Sickle Cell Disease, Thalassemia, Diamond-Blackfan Anemia
- Trial name
- MCSIO (NCT01114776)
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Iron-deficiency, Iron Deficiency Anemia
Effects of Enhancers and Inhibitors on Absorption From Iron Supplements
Iron deficiency (ID) is a major public health problem worldwide and oral iron supplementation can be an effective strategy to treat and prevent ID.
- Trial name
- NCT05414474
- Testing
- Reference, Ascorbic acid (AA) 500 mg, Ascorbic acid (AA) 80 mg
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Thalassemia Major, Chronic Blood Transfusion Related Iron Overload
MR Imaging of Diffuse Myocardial Fibrosis in Transfusion-Dependent Anemias
Cardiac failure is the major cause of death in patients with thalassemia and chronic blood transfusion-related iron overload. The treatment of thalassemia has been revolutionized over the past decade with the implementation of…
- Trial name
- MAFIO (NCT02090699)
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Colon Cancer, Chemotherapeutic-Induced Anemia
Intravenous Iron Infusion on Chemotherapy-induced Anemia
FOLFOX, the first-line regimen based on 5-FU and oxaliplatin, is adjuvant chemotherapy for pathologic stage II/III colorectal cancer patients.
- Trial name
- NCT05299411
- Testing
- iron (isomaltoside), Dried Ferrous Sulfate
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Hemodialysis
Association Between Depression and Iron Metabolism in Hemodialysis Patients
This study assesses the association of depression symptoms and iron metabolism in patients undergoing hemodialysis.
- Trial name
- NCT03096626
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Yoshihiro Tsuji
Anemia
A Study of the Electrocardiogram Effects and Pharmacokinetics of Ferumoxytol in Healthy Men and Women
This study will define the effects of ferumoxytol on electrocardiogram (ECG) data as well as evaluate pharmacokinetics
- Trial name
- NCT00360425
- Testing
- ferumoxytol, moxifloxacin
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- AMAG Pharmaceuticals, Inc.