Clinical trials: Iron Bioavailability
Iron-deficiency
Sucrosom5al Iron Supplementation in Blood Donors
The aim of this descriptive/explorative pilot study is to examine the effects of supplementing a sucrosomial iron preparation in whole blood donors with iron deficiency for three months.
- Trial name
- NCT04250298
- Testing
- sucrosomial iron
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Iron Deficiency
Relative Bioavailability of Ferric Pyrophosphate From an Apple Juice Drink
The aim of this study is to find out how well iron is absorbed when a newly developed form of ferric pyrophosphate is added to a commercial apple juice drink.
- Trial name
- NCT00474682
- Testing
- Micronized dispersible ferric pyrophosphate
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Iron Deficiency (Without Anemia)
Effect of Chitin and Ascorbic Acid on Dietary Insect Iron Absorption
Iron is involved in many vital metabolic processes such as oxygen transport, electron transport in cells, DNA synthesis and repair, and muscle metabolism.
- Trial name
- INSECTE (NCT06822062)
- Testing
- Meal A, Meal B, Meal C
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Distance University of Applied Sciences
Iron Deficiency, Anemia
The Optimization of Bioavailability From Iron Supplements: Study 1
Iron deficiency (ID) with or without anaemia (IDA) is a major public health problem worldwide, especially in women of reproductive age and young children.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT02175888
- Testing
- Daily administration of 60 mg iron in form of ferrous sulphate capsules for 14 consecutive days, Administrations of 60 mg iron in form of ferrous sulphate capsules on every second day for 28 days
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency, Iron Deficiency Anemia
Iron Bioavailability From Biofortified Orange-fleshed Sweet Potato
To combat iron deficiency in Low and Middle-Income Countries, sustainable food-based solutions have to be implemented to serve populations, not only individuals.
- Trial name
- SASHA-II (NCT03840031)
- Testing
- High Fe OFSP meal labelled with Fe-58, Control OFSP meal labelled with Fe-57
- Where
- 2 sites in Malawi, Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Iron-Deficiency
Tea Consumption and Iron Bioavailability in Women Using a Stable Isotope
The purpose of this study is to investigate the inhibition effect of tea consumption on non haem iron absorption with the use of an iron tracer.
- Trial name
- NCT02365103
- Testing
- Test meal I (given with water), Test meal II (simultaneously with tea), Test meal III (1 hour after test meal)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chester
IBD, Hypertension (HTN)
Acceptability, Adherence, and Impact on the Bioavailability of Iron and Zinc of the Dietary Supplements Goodphyte IB Defense and Goodphyte Immunity in Adults With Chronic Diseases.
The primary objective of the present postdoctoral research is to evaluate the acceptability and adherence of two dietary supplements containing microbial phytase, Goodphyte IB Defense and Goodphyte Immunity, in adult individuals…
- Conditions
- IBD, Hypertension (HTN), Multiple Sclerosis, Anemia
- Trial name
- PHYTASE (NCT07380022)
- Testing
- Dietary supplement intervention Goodphyte IB Defense, Dietary supplement intervention Goodphyte Immunity
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Vitamin A Deficiency
Impact of Consumption of Orange-fleshed Sweet Potatoes on the Vitamin A Status of Bangladeshi Women of Reproductive Age
The primary purpose of this study is to determine whether daily consumption of orange-fleshed sweet potatoes increases the vitamin A status of Bangladeshi women of reproductive age.
- Trial name
- NCT00453648
- Testing
- White-fleshed sweet potatoes, Orange-fleshed sweet potatoes (boiled), Orange-fleshed sweet potatoes (fried)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Bioavailability
A Stable Isotope Study to Evaluate the Bioavailability of an Oat Protein-based Iron Delivery System
In the current study, the OAT fibril - Fe SA (Fe-oat 1) and OAT fibril - Fe NaOH (Fe-oat 2) will both be studied in vivo, alone are oat fibril powder add iron supplement is soluble in water and oat fibril powder add iron…
- Trial name
- NCT05826899
- Testing
- 54Fe SO4, 57Fe Oat-1, 58Fe Oat-2
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Rainforest Company
Iron-refractory, Iron-deficiency Anemia (IRIDA)
Pharmacokinetics and Absolute Bioavailability of Fer-In-Sol and Triferic Administered Orally With Shohl's Solution in Healthy Volunteers
The main purpose is to determine the pharmacokinetics (PK) of Triferic iron administered orally in healthy adult volunteers. It is a randomized multiple treatments, single dose study.
- Trial name
- NCT02767128
- Testing
- Triferic, Fer-In-Sol, Shohl's solution
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Iron-deficiency
Effect of Polyphenols on Absorption of Iron From Sodium Iron Chlorophyllin
Polyphenols present in tea are known to inhibit the absorption of non heme iron. The inhibiting effect of tea on non-heme iron absorption is attributed to the flavonoids present in tea.
- Trial name
- polySIC (NCT04849832)
- Testing
- SIC, SIC + tea, FeSO4
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy Volunteers
Iron Bioavailability From Dairy Product
Determination of fractional iron absorption from dairy product fortified with 2 labelled iron compounds
- Trial name
- NCT02585661
- Testing
- Dairy product fortified with enriched Fe-54 salt (1), Dairy product fortified with enriched Fe-57 salt (2)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Iron Deficiency
Evaluation of Iron Bioavailability From Iron Chlorophyllin
The overall objective of this study is to evaluate the iron absorption from iron chlorophyllin. Iron deficiency is a public health problem in both developing and industrialized countries.
- Trial name
- NCT04602247
- Testing
- SIC, SIC + AA combined, FeSO4
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency, Anemia
The Optimization of Bioavailability From Iron Supplements: Study 2
Iron deficiency (ID) with or without anaemia (IDA) is a major public health problem worldwide, especially in women of reproductive age and young children.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT02177851
- Testing
- Single oral iron dose of 120 mg per day for 3 consecutive days, Two oral iron doses of 60 mg per day (morning + afternoon) for 3 consecutive days
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy
Relative Bioavailability of Two Formulations of AKB-6548 and the Food Effect of a New Tablet in Healthy Adult Subjects
The primary purpose of this study is to compare the PK parameters of a single dose of a test tablet formulation of AKB-6548 relative to a single dose of the reference AKB-6548 tablet formulation, both treatments administered…
- Trial name
- NCT02412449
- Testing
- AKB-6548 tablet, reference formulation given in the fasted state, AKB-6548 tablet, test formulation given in the fasted state., AKB-6548 tablet, test formulation given in the fed state
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Akebia Therapeutics
Iron-deficiency, Iron Deficiency Anemia
IP Peru, Bioavailability of Iron From Potatoes
To combat iron deficiency in Low and Middle-Income Countries, sustainable food-based solutions have to be implemented to serve populations, not only individuals.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
- Trial name
- IPPERU (NCT04216030)
- Testing
- High Fe IP meal labelled with Fe-58, Control OFSP meal labelled with Fe-57
- Where
- Peru
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Iron Isotope Study of an Iron Fatty Acid Complex
The study aims at assessing the iron (Fe) bioavailability from a newly developed iron compound - an iron fatty acid complex. The iron from the compound is hypothesized to have a higher absorption rate than commonly available…
- Trial name
- IFAC (NCT03895424)
- Testing
- IFAC, MIFAC, Control Ferrous Sulfate
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Iron Deficiency, Cardiometabolic Disease
The Impact of Faba Bean Rich Bread on Iron Status, Postprandial Lipaemia and Satiety
High levels of animal proteins (meat) in the diet are linked with a greater risk of developing heart disease and other long-term health conditions.
- Conditions
- Anemia, Iron Deficiency, Cardiometabolic Disease, Low Iron Stores
- Trial name
- RtP (NCT06466746)
- Testing
- Raising the Pulse faba bean-enriched bread, Conventional White Bread
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Reading
Nutritional Deficiency
Bioavailability of Zinc and Iron From a Whey-based Protein Supplement Consumed With a Habitual Plant-based Diet
Bioavailability of iron and zinc from habitual plant-based diets consumed by young children in Mexico is low due to the high phytate content.
- Trial name
- NCT02208622
- Testing
- Study 1: Whey Supplement Day 1, Study 1: Whey Supplement Day 2, Study 2: Whey Supplement
- Where
- 2 sites in United States, Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Deficiency
Iron Bioavailability From Cubes
Iron deficiency is a highly prevalent nutrient deficiency which is a public health problem, especially in developing countries. There are several strategies to correct iron deficiency in populations: besides supplementation with…
- Trial name
- Fe Bouillon (NCT02327299)
- Testing
- Bouillon fortified with FePP, Bouillon fortified with FePP + Stabilizer, Bouillon fortified with FeSO4
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology