Clinical trials: Iron Deficiencies
Iron-deficiency Anemia (IDA), Hemoglobin
Comparison of Ferrous Salt vs. Liposomal Iron in Adult Women With Iron-Deficiency Anemia
The goal of this study is to compare ferrous salt and liposomal iron for the treatment of iron-deficiency anemia in adult women. The study will also evaluate how well each treatment is tolerated.
- Conditions
- Iron-deficiency Anemia (IDA), Hemoglobin, Iron Deficiencies, Adverse Effect
- Trial name
- IDA (NCT07556731)
- Testing
- Oral ferrous fumarate administered every 24 hours, Ferrous fumarate administered orally every 48 hours., Liposomal iron formulation.
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Hospital General de Mexico
Pregnancy
Iron Absorption From IFA and MMS Supplements in Kenyan Women During the Second Trimester of Pregnancy
This study evaluates iron absorption from three antenatal supplements, 30 mg MMS, 60 mg MMS, and 60 mg IFA, in 50 pregnant Kenyan women in their second trimester.
- Trial name
- PROUD (NCT07435766)
- Testing
- MMS with 30 mg iron, MMS with 60 mg iron, IFA with 60 mg iron
- Where
- 2 sites in Kenya
- Volunteers
- 50 people
- Sponsor
- ETH Zurich
Iron Deficiency, HIV
Potential of Prebiotic Galacto-oligosaccharides in Improving Efficacy and Safety of Oral Iron Supplementation in HIV-infected Children
The objectives of this randomized controlled trial in virally suppressed HIV-positive children with anemia and/or depleted iron stores are to determine the effect of prebiotic galacto-oligosaccharides (GOS) as adjunct treatment…
- Trial name
- NCT04931641
- Testing
- Galacto-oligosaccharides, Maltodextrin, Ferrous fumarate
- Where
- South Africa
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency Anemia
Use of Cast Iron Pots to Improve Maternal Anemia
Anemia of pregnancy is defined as a hemoglobin concentration of less than 11 g/dL in the first and third trimesters, and less than 10.5 g/dL in the second trimester.
- Trial name
- NCT02341300
- Testing
- Cast Iron Pot, Alumnium Pot
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Iron Deficiency Anemia
Effect of Multiple Micronutrient Fortified Bread Consumption on Iron Deficiency Anemia in Women of Reproductive Age
The project aims to assess if consuming two slices of multi-fortified bread daily for 120 days is effective in reducing iron deficiency anemia in women of reproductive age through a three-arm randomized trial.
- Trial name
- NCT05103709
- Testing
- MULTI-FORTIFIED, FORTIFIED
- Where
- Peru
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Iron Deficiency (Without Anemia)
Plasma Hepcidin Response to Differently Dosed Iron Supplements
The study participants will take 3 different doses of iron supplements at 8 am, on 3 different days. By taking blood samples in the morning and afternoon, the investigators will determine the effects of the iron supplements on…
- Trial name
- NCT04735848
- Testing
- Iron-supplement application
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Pierre-Alexandre Krayenbuehl
Iron Deficiency Anemia
Pharmacokinetics, Pharmacodynamics and Safety Study of Z-213 to Iron Deficiency Anemia
The safety, tolerability, pharmacokinetics and pharmacodynamics of Z-213 will be investigated in patients with iron-deficiency anemia after administration of a single dose (100 mg, 500 mg, 800 mg or 1,000 mg iron).
- Trial name
- NCT02170311
- Testing
- Z-213
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Zeria Pharmaceutical
Anemia, Iron Deficiency
Effects of Ferinject® on Anemia and Transfusion Rates After Cardiac Surgery
Several studies using new forms of intravenous iron showed that it is effective in treating perioperative anemia in orthopedic and digestive surgery.
- Trial name
- FCAACS (NCT03759964)
- Testing
- Ferric carboxymaltose
- Where
- Lebanon
- Volunteers
- 194 people
- Sponsor
- St Joseph University, Beirut, Lebanon
Anemia, Anemia (Iron-Loading)
Evaluate the Outcomes of Ferric Carboxymaltose in Patients With Perioperative Anemia
The prevalence of preoperative anaemia in patients undergoing major surgery is approximately 30%, and is independently associated with higher mortality, a higher rate of postoperative complications, and a greater probability of…
- Conditions
- Anemia, Anemia (Iron-Loading), Perioperative Bleeding, Infection Prevention
- Trial name
- NCT06948864
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- Spain
- Volunteers
- 152 people
- Sponsor
- Hospital Universitario Infanta Cristina
Heart Failure
New Pathophysiological Pathways Involved in Iron Metabolism Disorder in Heart Failure
The aim of our study is to understand the biological pathways involved in the occurrence of IDy in patients with HF since ID is very common and supposes a negative impact in terms of clinical outcomes in these patients.
- Trial name
- IRON-PATH II (NCT05000853)
- Testing
- Iron Carboxymaltose
- Where
- 2 sites in Spain
- Volunteers
- 210 people
- Sponsor
- Hospital Universitari de Bellvitge
Iron Deficiency (Without Anemia), Pregnancy
Iron Parameters in Non-anemic First Trimester Gravidas
The purpose of the study is to see the percentage of non-anemic, first trimester gravidas presenting to their obstetricians, who are iron deficient.
- Trial name
- NCT03670537
- Testing
- Iron parameters
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Auerbach Hematology Oncology Associates P C
Anemia, Iron-Deficiency
Non-invasive Optical Detection of Iron Deficiency
This study aims to evaluate a prototype device detecting zinc protoporphyrin-IX fluorescence non-invasively from the intact oral mucosa. Zinc protoporphyrin-IX is an established indicator of iron deficiency.
- Trial name
- NCT02310607
- Testing
- Not an interventional study
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Klinikum der Universitaet Muenchen, Grosshadern
Iron Overload, Oxidative Stress
Effects of Taking Prenatal Vitamin-mineral Supplements During Lactation on Iron Status and Markers of Oxidation
Most breastfeeding women are told by their health care provider to continue taking prenatal vitamins after they give birth. A woman's requirement for iron while breastfeeding is low, yet prenatal vitamins contain a large amount…
- Conditions
- Iron Overload, Oxidative Stress, Iron-deficiency Anemia
- Trial name
- NCT01047098
- Testing
- Iron
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity, Iron Deficiency Anemia
Effect of Weight Loss on Hepcidin Levels and Iron Status in Subjects With Obesity.
Obesity and iron deficiency are the nutritional disorders with the highest prevalence worldwide. Different mechanisms have been proposed to explain iron deficiency secondary to obesity.
- Trial name
- NCT06104800
- Testing
- Calorie-restricted diet with red meat, Calorie-restricted diet without red meat
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Vitamin A Deficiency, Iron Deficiency
An Efficacy Trial of Iron, Zinc and Vitamin A Fortified Rice in Children in Satun, Thailand
Iron, zinc and vitamin A deficiencies are particularly common among children and young women in the developing countries of South and Southeast Asia resulting in important adverse health effects.
- Conditions
- Vitamin A Deficiency, Iron Deficiency, Zinc Deficiency
- Trial name
- NCT01061307
- Testing
- fortified extruded rice
- Where
- 2 sites in Switzerland, Thailand
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia, Infectious Diseases
Efficacy Trial to Examine Efficacy of Multimicronutrient Home Supplementation in Infants
The objective of the program is to examine the efficacy of 6 month home micronutrient supplementation in Bedouin and Jewish children on improvements in nutritional status including measures of iron, ferritin, zinc and folic acid…
- Conditions
- Iron Deficiency Anemia, Infectious Diseases, Undernutrition
- Trial name
- NCT00276198
- Testing
- Sprinkles, Ferripel-3, Vitamins A&D drops
- Where
- Israel
- Volunteers
- 771 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Newborn; Vitality, Iron Deficiency Anemia
The Importance of Delayed Cord Clamping
After birth, the umbilical cord is usually clamped and separated from the placenta within the first 30 seconds. Although the exact time to clamp the umbilical cord is unknown, allowing placental transfusion after birth has many…
- Trial name
- NCT06405867
- Testing
- delayed cord clamping (> 60 sec)
- Where
- Turkey (Türkiye)
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Iron Deficiency Anemia Due to Blood Loss, Aortic Stenosis
IV Sodium Ferric Gluconate Complex in Patients Undergoing TAVI
Iron deficiency is common among patients undergoing TAVI. It is estimated at 54-79%. Previous non-randomized small trial have shown symptomatic benefit in treating iron deficiency in this group of patients.
- Trial name
- NCT04797832
- Testing
- IV Sodium Ferric Gluconate Complex
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rambam Health Care Campus
Chronic Kidney Disease, Iron Deficiency
Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency
The main objective of the study is to compare the impact of oral ferric citrate compared to standard of care oral ferrous sulfate on serum iron, percent transferrin saturation, ferritin, hepcidin and hemoglobin levels in…
- Conditions
- Chronic Kidney Disease, Iron Deficiency, Anemia
- Trial name
- NCT02888171
- Testing
- ferric citrate, ferrous sulfate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Heart Failure With Normal Ejection Fraction, Ferropenic Anemia
Effects of Iron Therapy in Heart Failure With Preserved Ejection Fraction and Iron Deficiency (PREFER-HF)
The purpose of the study is to evaluate whether the administration of iron to patients with heart failure and preserved ejection fraction results in an improvement of symptoms and functional class, in addition to evaluating…
- Trial name
- PREFER-HF (NCT03833336)
- Testing
- Ferric carboxymaltose, Ferroglycine Sulfate, Sucrosomial Iron
- Where
- 2 sites in Spain
- Volunteers
- 72 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida