Clinical trials: Iron Deficiency
Iron Deficiency
Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality
Primary Hypothesis The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use.
- Trial name
- DIDS (NCT02889133)
- Testing
- Iron-dextran, Saline, Blood Donation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Columbia University
Iron-deficiency
Effect of Iron-fortified Pea Powder on Exercise Performance
Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study assesses the impact of an pea protein supplement with high iron bio-availability on iron status and exercise…
- Trial name
- NCT04872140
- Testing
- Low phytate pea powder, Regular pea powder
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Hookworm Infection, Hookworm Disease
Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults
Na-GST-1 and Na-APR-1 are proteins expressed during the adult stage of the Necator americanus hookworm life cycle that are thought to play a role in the parasite's degradation of host hemoglobin for use as an energy source.
- Trial name
- NCT02126462
- Testing
- Na-APR-1 (M74)/Alhydrogel®, Na-GST-1/Alhydrogel®, Hepatitis B vaccine
- Where
- Gabon
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Iron-deficiency
Iron Bioavailability of High Surface Area Ferric Phosphate
The primary objective of this study is to compare iron absorption of high surface area ferric phosphate with that of ferrous sulfate and bulk ferric phosphate in a rice-based meal in non-pregnant women.
- Trial name
- HiFe (NCT03660462)
- Testing
- FeSO4 fortified rice test meal, FePO4 fortified rice test meal, HiFePO4 1 fortified rice test meal
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Impact of Iron Injection on Blood Donation
This trial study and compare in blood and urinary matrices the impact of an iron injection on proteins involved in iron metabolism during a blood donation.
- Trial name
- FERDOP (NCT03014921)
- Testing
- iron injection, saline solution injection
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Nicolas Leuenberger
Iron Deficiency Anemia
Effect of Nutrition Education on Vegetable and Legume Intake Among Households in Accra
The main purpose of this observational study is to determine the effect of nutrition education on the knowledge and behaviour of households towards the consumption of green leafy vegetables, legumes and vitamin C-rich fruits and…
- Trial name
- NCT07012473
- Testing
- Nutrition education on green leafy vegetables and legumes
- Where
- Ghana
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Ghana
Anemia, Iron Deficiency
Efficacy of Double Fortified Salt (DFS) to Improve Work Productivity in Women in India
The main objective of the present study is to assess the impact of double fortified salt containing iron and iodine on work performance (productivity) of women plantation workers in India.
- Trial name
- DFS (NCT01032005)
- Testing
- double fortified salt
- Where
- India
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Micronutrient Initiative
Premenopause, Iron-deficiency
A Clinical Study on Adherence and Efficacy of Different Doses of Active Iron in Treatment Resistant Subjects
A randomized, placebo controlled, parallel group, double blind study to compare the 3-month adherence and efficacy of Active Iron in subjects with or at-risk of iron deficiency and a history of intolerance to oral iron.
- Conditions
- Premenopause, Iron-deficiency, Iron Adverse Reaction, Iron Deficiency Anemia
- Trial name
- NCT04778072
- Testing
- Ferrous sulfate 14mg once daily, Ferrous sulfate 25mg once daily, Ferrous sulfate 25mg twice daily
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Solvotrin Innovations Ltd
Anemia, Iron-deficiency Anemia
Neurovascular Complications and White Matter Damage in Acquired Anemias
This is an observational trial, in patients with moderate to severe anemia and control subjects. The main purpose of this study is to understand whether normal brain blood flow, oxygen extraction reserve, white matter volumes…
- Conditions
- Anemia, Iron-deficiency Anemia, Healthy Controls
- Trial name
- NCT04320966
- Where
- 4 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Anemia, Iron Deficiency, Iron Overload
Ethnic Differences in Iron Absorption (FeGenes)
This study aims to; 1) investigate population differences in iron absorption between East Asians and Northern Europeans; 2) assess population differences in hormonal and biochemical determinants of Fe absorption between East…
- Trial name
- FeGenes (NCT04198545)
- Where
- 2 sites in United States
- Volunteers
- 515 people, healthy volunteers welcome
- Sponsor
- Cornell University
Iron-Deficiency Anemia, Pregnancy
Different Iron Supplements for Prevention of Anemia in Pregnancy
Examination of iron supplements routinely used in pregnancy to compare these with one another regarding effectiveness in the prevention of iron deficiency.
- Trial name
- EDISA (NCT02487719)
- Testing
- Iron sulfate and Iron polymaltose for prevention of iron deficiency anemia
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Iron Deficiency
Iron-fortified Flavoured Skimmed Milk With or Without Vitamin D in Iron Deficient Women
Iron deficiency and vitamin D deficiencies are common in menstruating women. The present assay studied the influence of the consumption of a flavoured skimmed milk with iron (iron pyrophosphate) or with iron and vitamin D3 in…
- Trial name
- NCT01739907
- Testing
- Iron fortified flavoured skimmed milk with or without vitamin D in iron deficient women
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis
Kids With Iron Deficiency and Scoliosis
This study is a randomized controlled trial of preoperative oral iron supplementation, to identify whether iron deficiency is a modifiable risk factor for adverse surgical outcomes such as red blood cell transfusion and…
- Conditions
- Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies
- Trial name
- KIDS (NCT06042699)
- Testing
- Oral ferrous sulfate
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Columbia University
Fatigue, Low Mood
A Study to Evaluate the Effects of a Beef Liver Supplement on Energy, Mood, and Mental Clarity
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the Ancestral Supplements Grass Fed Beef Liver oral supplement on energy, mood, and mental clarity over 12 weeks.
- Conditions
- Fatigue, Low Mood, Mental Clarity, Iron Deficiency
- Trial name
- NCT07892911
- Testing
- Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ancestral Supplements, LLC
Inflammatory Bowel Disease, Iron Deficiency Anemia
EffiCacy and sAfEty of Low doSe orAl iRon for Anaemia in IBD
Iron deficiency anaemia (IDA) is common in inflammatory bowel disease (IBD). However, although iron is commonly prescribed, the amount of elemental iron needed to achieve clinical efficacy, and the optimal method of…
- Trial name
- CAESAR (NCT06321887)
- Testing
- Ferrous fumarate syrup 2.5ml/70mg (22.5mg elemental iron), Ferrous fumarate syrup 2.5ml/70mg(45mg elemental iron), Ferrous fumarate syrup 2.5ml/70mg (90mg elemental iron)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Hookworm Infection, Hookworm Disease
Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian Adults
This two part study will evaluate the safety and immunogenicity of two formulations of Na-GST-1, first in hookworm-naïve individuals using an open-label design, and then in adults living in an area of endemic hookworm infection…
- Trial name
- NCT01261130
- Testing
- 10 μg Na-GST-1/Alhydrogel, 30 μg Na-GST-1/Alhydrogel, 100 μg Na-GST-1/Alhydrogel
- Where
- 2 sites in Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Nutritional Status, Iron-deficiency
Assessing Dietary Intake of Selected Food Components Using Short Questionnaires
The aim of the study is to validate short questionnaires for assessing dietary intake of selected food components, with a focus on dietary fibre and iron.
- Conditions
- Nutritional Status, Iron-deficiency, Diet
- Trial name
- NutriPlant/FFQ (NCT07442305)
- Testing
- 5d-PD: Nutritional intakes using 24-h food recalls, KV-PV: Dietary fibre intake, KV-Fe: Iron intake
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption
A Study to Investigate the Effect of Vitamin D3 Supplementation on Iron Status in Iron Deficient Women
Iron is one of the most vital elements in humans as it plays a role in physiological functions such as transferring and storing oxygen, transporting electrons and catalysing numerous reactions, from oxidative metabolism to…
- Conditions
- Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption, Vitamin D Deficiency
- Trial name
- NCT02714361
- Testing
- Vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chester
Nutritional Disorder, Hypertension
The Influence of Hypotensive Drugs on Mineral Status in Experimental and Clinical Studies
The aim of the study was to evaluate the effects of hypotensive treatment combined with a higher zinc supply in the diet and supplements on the mineral status and selected biochemical parameters of newly diagnosed hypertensive…
- Conditions
- Nutritional Disorder, Hypertension, Mineral Deficiency
- Trial name
- NCT03465462
- Testing
- group/arm C (control group), group/arm D (diet group), group/arm S (supplementation group)
- Where
- Poland
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Anemia, Iron-Deficiency
Effect of Umbilical Cord Milking on Iron Related Health Outcomes for Cesarean-Delivered Infants
This study aims to determine whether umbilical cord milking can improve iron related health outcomes for cesarean-delivered infants.
- Trial name
- NCT02892461
- Testing
- Umbilical cord milking
- Where
- 2 sites in China
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Peking University