Clinical trials: Iron Deficiency in Pregnancy
Iron Deficiency, Anaemia
Switch From Oral Iron to Intravenous Ferric Carboxymaltose in Non-dialysis Chronic Kidney Disease (CKD)
Investigation whether a switch from oral iron to intravenous ferric carboxymaltose can reduce dose requirements of erythropoiesis-stimulating agents (ESA) and improve Hb levels and iron status in adult patients with…
- Trial name
- NCT02232906
- Testing
- intravenous ferric carboxymaltose
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Hospital Aleman
Premenopause, Iron-deficiency
A Clinical Study on Adherence and Efficacy of Different Doses of Active Iron in Treatment Resistant Subjects
A randomized, placebo controlled, parallel group, double blind study to compare the 3-month adherence and efficacy of Active Iron in subjects with or at-risk of iron deficiency and a history of intolerance to oral iron.
- Conditions
- Premenopause, Iron-deficiency, Iron Adverse Reaction, Iron Deficiency Anemia
- Trial name
- NCT04778072
- Testing
- Ferrous sulfate 14mg once daily, Ferrous sulfate 25mg once daily, Ferrous sulfate 25mg twice daily
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Solvotrin Innovations Ltd
Iron Deficiency, Anemia of Prematurity
Neurodevelopment After Early Iron Supplementation
Background: Iron deficiency in early childhood may impair neurodevelopment. Aim: To examine whether early iron supplementation improved neurodevelopment in preterm infants.
- Conditions
- Iron Deficiency, Anemia of Prematurity, Neurodevelopmental Delay
- Trial name
- NCT00457990
- Testing
- Oral administration of ferrous sulphate
- Where
- Germany
- Volunteers
- 204 people
- Sponsor
- University of Ulm
Anemia of Chronic Kidney Disease
KRX-0502 (Ferric Citrate) for the Treatment of IDA in Adult Subjects With NDD-CKD
a 24-week phase 3, multi-center clinical trial, comprised of a 16-week, randomized, double-blind, placebo-controlled period ("Randomized Period"), followed by an 8-week open-label safety extension period, where all subjects…
- Trial name
- NCT02268994
- Testing
- ferric citrate
- Where
- 36 sites in United States
- Volunteers
- 234 people
- Sponsor
- Keryx Biopharmaceuticals
Iron Deficiency Anemia in Pregnancy, Iron Deficiency in Pregnancy
Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant Women
The clinical study aims to evaluate the effect of iron supplementation in preventing the onset of Iron Deficiency Anemia during pregnancy.
- Trial name
- NCT07884617
- Testing
- Iron plus folic acid, Folic acid
- Where
- Italy
- Volunteers
- 162 people
- Sponsor
- IBSA Farmaceutici Italia Srl
Prematurity, Iron-deficiency
Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants
In this phase II trial, the investigators overarching goal is to demonstrate the feasibility and potential benefit of darbepoetin (Darbe) plus slow-release intravenous (IV) iron to decrease transfusions, maintain iron sufficiency…
- Conditions
- Prematurity, Iron-deficiency, Iron Deficiency Anemia, Iron Malabsorption
- Trial name
- DIVI (NCT05340465)
- Testing
- Darbepoetin Alfa, Low Molecular Weight Iron Dextran, Ferumoxytol injection
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Washington
Iron Deficiency Anemia of Pregnancy
Iron Deficiency Anaemia in Pregnant Patients Presenting for Antenatal Care
This is a cross-sectional, prospective study of iron deficiency anaemia among pregnant patients presenting for antenatal care at a secondary level institution in the Western Cape, Mowbray Maternity Hospital, over a one-week…
- Trial name
- NCT05157828
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 132 people
- Sponsor
- University of Cape Town
Anemia, Iron Deficiency, Heavy Menstrual Bleeding
IV Iron vs Oral Iron for Treatment of Anemia in Women With Abnormal Uterine Bleeding
This study investigates whether intravenous (IV) iron [Feraheme (ferumoxytol) injection)] is a better treatment than oral iron pills (ferrous sulfate) for correcting anemia in women who have heavy menstrual bleeding and anemia.
- Trial name
- NCT04205266
- Testing
- Ferumoxytol, Ferrous Sulfate
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Iron Deficiency
Pregnancy Outcome in Women With an Iron Deficiency in the First Trimester
The primary aim of this retrospective, monocentric study with two parallel groups is to investigate pregnancy outcome in women with iron deficiency in the first trimester.
- Trial name
- NCT05262634
- Testing
- Data collection (laboratory and obstetric results)
- Where
- Switzerland
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Iron-deficiency Anemia (IDA), Pregnancy
Oral Iron Supplementation on Alternate vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
This will be a randomized clinical trial. Enrolled subjects will be randomized (1:1) into two study arms to receive either daily (Group 1) or alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate…
- Trial name
- NCT06492512
- Testing
- daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill, alternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Southern Illinois University
Iron Deficiency Anemia
Lactoferrin Versus Ferrous Sulfate in Iron-deficiency During Pregnancy
The main drawbacks with oral iron are side-effects, poor compliance, and limited absorption from the gut. It has become very apparent gastrointestinal intolerance with oral iron therapy is dose related and common (up to 20% of…
- Trial name
- NCT03759353
- Testing
- Baseline ferritin level, Lactoferrin, Ferrous Sulfate
- Where
- Egypt
- Volunteers
- 98 people
- Sponsor
- Ain Shams University
Iron Deficiency Anaemia in Childbirth
Ferric Derisomaltose (Iron Isomaltoside) Versus Iron Sucrose for Treatment of Iron Deficiency in Pregnancy
Ion deficiency anemia (IDA) is associated with poor neonatal outcomes and maternal morbidity. Iron replacement may be done with oral iron or intravenous iron, with intravenous iron being utilized later in pregnancy or if there is…
- Trial name
- NCT05251493
- Testing
- Iron Isomaltoside 1000, ferric derisomaltose, Iron sucrose
- Where
- Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Iron Deficiency Anemia
Lactoferrin Versus Total Dose Infusion (TDI) For Treating Iron Deficiency Anemia in Pregnancy: Role of Nursing
This study consisted of 60 cases. All the cases of pregnant women are 4 months to 8 months of pregnancy. The cases divided into 30 pregnant women's were given iron supplementation without health education and another 30 were…
- Trial name
- TDI (NCT03279536)
- Testing
- Oral lactoferrin, TDI of LMW iron dextran
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Woman's Health University Hospital, Egypt
Iron Deficiency
Absorption of Heme and Non-Heme Iron in Pregnant and Non-pregnant Women and Mechanisms of Fetal Iron Transfer
The three specific aims of this study are 1) to assess the impact of iron status on relative differences in absorption of heme and non-heme iron among pregnant women and non-pregnant women, 2) to assess the magnitude and the…
- Trial name
- NCT01019096
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cornell University
Pregnancy Related, Iron Deficiency Anemia of Pregnancy
Daily Versus Alternate Day Iron Supplementation for the Treatment of Iron Deficiency Anemia in Pregnancy
The target population for our study is pregnant women in the first or second trimester with a diagnosis of iron deficiency anemia. If a subject is eligible, written consent will be obtained by person to person contact.
- Trial name
- NCT04594070
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Iron Deficiency, Iron Deficiency Anemia
Ferric Citrate in Managing Serum Phosphorus and Iron Deficiency in Anemic Chronic Kidney Disease (CKD) Subjects Not on Dialysis
The purpose of this study is to determine if KRX-0502 (ferric citrate) is a safe and effective treatment for the management of serum phosphorus levels and iron deficiency in anemic chronic kidney disease (CKD) stage 3-5 subjects…
- Trial name
- NCT01736397
- Testing
- Ferric Citrate
- Where
- 20 sites in United States
- Volunteers
- 149 people
- Sponsor
- Keryx Biopharmaceuticals
Treatment of Iron Deficiency Anemia in Pregnancy
Iron Supplementation Using Total Dose Infusion and Oral Routes for Treatment of Iron Deficiency Anemia in Pregnancy
Evaluate the effect of iron supplementation using oral routes in comparison with total dose infusion of low molecular weight iron dextran in iron deficiency anemia during pregnancy.
- Trial name
- NCT02086838
- Testing
- Theragran Hematinic, low molecular weight iron dextran
- Where
- Egypt
- Volunteers
- 212 people
- Sponsor
- Ain Shams University
Anemia of Chronic Kidney Disease
Effect of Adding Lactoferrin on Oral Iron on Anemia in Chronic Kidney Disease Patients
The aim of this study is to evaluate the effects of adding lactoferrin to the every-other-day oral iron supplementation in iron deficiency anemia and chronic kidney disease patients.
- Trial name
- NCT05900635
- Testing
- Lactoferrin, Ferrous Glycine Sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Iron Deficiency Anemia
A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia in Pediatric Participants With Chronic Kidney Disease
Study AMAG-FER-CKD-253 is an extension study of the combined AMAG-FER-CKD-251 (NCT01155375) and AMAG-FER-CKD-252 (NCT01155388) studies to evaluate the efficacy and safety of episodic treatment of iron deficiency anemia (IDA) with…
- Trial name
- NCT01264679
- Testing
- Ferumoxytol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Iron Deficiency Anemia of Pregnancy, Iron Storage Disease
Analysis of the Effect of Iron Supplements on Iron Deficiency Anemia in Pregnancy
Subjects were tested for hemoglobin, ferritin, serum iron, transferrin saturation and reticulocyte count during routine prenatal examination at 24-26 weeks of gestation, and blood samples were taken for serum hepcidin detection…
- Trial name
- NCT05804071
- Testing
- Niferex
- Where
- China
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital