Clinical trials: Iron-Deficiency
Iron Deficiency, Heart Failure
Study to Compare Ferric Carboxymaltose With Placebo in Patients With Acute Heart Failure and Iron Deficiency
Study to Compare Ferric Carboxymaltose With Placebo in Patients With Acute Heart Failure and Iron Deficiency (Affirm-AHF)
- Trial name
- Affirm-AHF (NCT02937454)
- Testing
- ferric carboxymaltose, Normal saline 0.9%
- Where
- 16 sites in Argentina, Brazil and 13 more
- Volunteers
- 1,132 people
- Sponsor
- Vifor (International) Inc.
Iron-deficiency, Iron Deficiency Anemia
Iron Deficiency in Female State Fair Attendees
This study aims to examine iron deficiency symptoms and biochemical iron status based on hemoglobin, hematocrit, ferritin, and total iron binding capacity in menstruating females.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
- Trial name
- NCT03228173
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anemia, Iron Deficiency, Iron Overload
Validation of a Point-of-care Device Measuring Ferritin With Capillary Blood
Measurement of iron is important for identifying both low and high iron levels in the body. Measuring a protein in the blood called ferritin is currently the easiest way to determine a patient's iron status.
- Conditions
- Anemia, Iron Deficiency, Iron Overload, Iron-deficiency
- Trial name
- FerPOC (NCT03800446)
- Testing
- Point of care ferritin test
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Anemia, Iron Deficiency
Patient Blood Management in the Approach to Prosthetic Surgery [PBM(L4178)]
We have been well guided in the "Good use of blood" during major surgery for many years, reaching a percentage of 4% of patients transfused after elective prosthetic operations.
- Trial name
- PBM(L4178) (NCT05806437)
- Testing
- sideremil vita cp
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Celiac Disease, Iron Deficiency (Without Anemia)
Effects of a Dietary Approach to Iron Deficiency in Premenopausal Women Affected by Celiac Disease
Anemia and sideropenia are a common effect of untreated celiac disease. In a portion of patients a certain degree of hypoferritinemia persist after the diagnosis, despite a good compliance and clinical response to gluten-free…
- Trial name
- NCT02949765
- Testing
- Iron sulfate 105 mg, Iron-rich diet
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Heart Failure
New Pathophysiological Pathways Involved in Iron Metabolism Disorder in Heart Failure
The aim of our study is to understand the biological pathways involved in the occurrence of IDy in patients with HF since ID is very common and supposes a negative impact in terms of clinical outcomes in these patients.
- Trial name
- IRON-PATH II (NCT05000853)
- Testing
- Iron Carboxymaltose
- Where
- 2 sites in Spain
- Volunteers
- 210 people
- Sponsor
- Hospital Universitari de Bellvitge
Pancreaticojuodenectomy
The Role of Intravenous Ferritin in Optimizing Postoperative Recovery Following Pancreaticoduodenectomy
Iron deficiency anemia is well known as a risk factor that worsens postoperative morbidity and patient prognosis. Several studies have shown that intravenous iron administration before surgery is effective in reducing the risk of…
- Trial name
- Ferritin (NCT06442111)
- Testing
- The intravenous ferritin group
- Volunteers
- 106 people
- Sponsor
- Seoul St. Mary's Hospital
Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization
Intravenous Iron Sucrose for Acute Decompensated Heart Failure Patients With Reduced Ejection Fraction and Iron Deficiency
Iron deficiency (ID) affects about 25% of the global population, presenting with symptoms of fatigue, weakness, and impaired cognitive function.
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization, Iron Deficiency
- Trial name
- IronSucroseHF (NCT06703411)
- Testing
- Iron Sucrose IV, Standard Medical Therapy
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Cheng-Hsin General Hospital
Haemodynamic Rebound
Iron Substitution After Total Knee Arthroplasty
Hemoboost is a registered natural product containing specially processed haemolysed haemoglobin and iron dextran. It is marketed for human use on the basis of many years' use and documented effect in veterinary medicine.
- Trial name
- NCT01611181
- Testing
- Hemoboost, Kräuterblut, Ferrofumerat
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Iron-deficiency, Heart Failure With Preserved Ejection Fraction
Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)
The primary objective of this study is to determine if the correction of functional iron deficiency by administering a single dose of intravenous iron (ferric derimaltose or Monoferric®) in participants with heart failure with…
- Trial name
- IRONMETHFpEF (NCT04945707)
- Testing
- Ferric Derisomaltose 1000 Mg in 100 mL INTRAVENOUS SOLUTION [Monoferric]
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Iron-deficiency
EXPLorative Data Collection for Patient chAracterIzation, treatmeNt Pathways and Outcomes of IRON Preparations
By describing the characteristics of iron deficiency (ID) patients treated with various oral or intravenous iron formulations and their outcomes, this registry will provide the medical community with important information to…
- Trial name
- EXPLAIN-IRON (NCT03382275)
- Testing
- Iron Supplement
- Where
- 2 sites in Germany
- Volunteers
- 51 people
- Sponsor
- GWT-TUD GmbH
Iron Deficiency Anemia, Iron Deficiency Anemia Treatment
Effectiveness of Oral Iron Therapy in Iron Deficiency Anemia With Daily vs Alternate Day Dosing
Treating iron deficiency anemia in children with daily and alternate day oral iron therapy
- Trial name
- NCT07267975
- Testing
- Ferrous sulphate
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Malnutrition; Mild, Iron-deficiency Anemia
The Effect of Fortified Growing-up Milk on Growth and Micronutrient Status of Nigerian Toddlers
It is well known than an important part of Nigerian children from the lower social economic class have nutrient deficiencies. Fortified products, such as growing up milks (GUM), may play an important role in reducing the risk and…
- Conditions
- Malnutrition; Mild, Iron-deficiency Anemia, Nutritional Stunting, Nutritional Wasting
- Trial name
- GaGA (NCT03411590)
- Testing
- Fortified milk Powder
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina WAMCO Nigeria PLC
Iron Deficiency Anemia
A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia
To evaluate the safety and efficacy of ferumoxytol for the episodic treatment of iron deficiency anemia (IDA).
- Trial name
- NCT01114217
- Testing
- Ferumoxytol
- Where
- 140 sites in United States, Canada and 4 more
- Volunteers
- 634 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Anemia
Iron Prophylaxis for Anemia in Infants With Cyanotic Congenital Heart Disease
Anemia is a common disorder in infants with one working chamber of the heart that pumps blood. Anemia is when the level of healthy blood cells becomes too low.
- Trial name
- NCT00459225
- Testing
- Iron (ferrous sulfate)
- Where
- United States
- Sponsor
- Emory University
Iron-deficiency
Iron Isotope Study of an Iron Fatty Acid Complex
The study aims at assessing the iron (Fe) bioavailability from a newly developed iron compound - an iron fatty acid complex. The iron from the compound is hypothesized to have a higher absorption rate than commonly available…
- Trial name
- IFAC (NCT03895424)
- Testing
- IFAC, MIFAC, Control Ferrous Sulfate
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Rendu Osler Disease
Calcium-phosphate Complications Induced by IV Iron Supplementation in Patients With Rendu-Osler Disease
Hypophosphatemia induced by treatments with injectable iron is a frequent side effect already reported during marketing. Situations of osteomalacia secondary to these hypophosphatemias are rarer and reported in the form of case…
- Trial name
- OS-LERETRO (NCT05544669)
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Strasbourg, France
Iron Deficiency Anemia Treatment, Microbial Colonization
GI Effects of Iron in Healthy Volunteers
Over recent years there has been a lot of research looking at how the bacteria in our gut affects our health. Some medications are known to cause changes in gut bacteria.
- Conditions
- Iron Deficiency Anemia Treatment, Microbial Colonization, Iron-deficiency, Iron Deficiency Anemia
- Trial name
- NCT04705662
- Testing
- Lactulose breath test, Stool sample, Daily Diary
- Where
- 2 sites in United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr Anthony Hobson
Iron Deficiency
Iron Absorption From Tef-injera in Women of Reproductive Age
Anemia is one of the most common health problems all over the world with around half of preschool-aged children (<5 years) and one third of women affected.
- Trial name
- NCT01687062
- Testing
- FeSO4, reduction of phytate, NaFeEDTA
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Absorption, Stable Isotope Appearance and Non-transferrin-bound Iron (NTBI) Profile From NaFeEDTA and Ferrous Sulphate
Several iron compounds are used for fortification, including ferrous sulphate and NaFeEDTA. The absorption profile of these may differ because of differences in their dissolution in the gastrointestinal tract and in their…
- Trial name
- SIA (NCT01053442)
- Testing
- Porridge fortified with either NaFeEDTA, FeSO4
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology