Clinical trials: Iron-Deficiency
Iron Deficiency, Anemia
Using Stable Iron Isotopic Techniques and Serum Hepcidin Profiles to Optimize Iron Supplementation
Oral iron supplementation (OIS) is a widely-used strategy to treat iron deficiency anemia. However, absorption of OIS is often low and response is variable.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT01785407
- Testing
- Iron Supplement (Ferrous Sulfate Dried)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia
To Assess the Impact of Ferric Carboxymaltose Compared With Iron Sucrose in Chinese Subjects on Correcting Iron Deficiency Anaemia
The primary objective is to demonstrate the efficacy of ferric carboxymaltose (FCM) given in a simple dosing regimen in correcting iron deficiency anaemia (IDA), by demonstrating non-inferiority to treatment with the currently…
- Trial name
- NCT03591406
- Testing
- Ferric carboxymaltose, Iron sucrose
- Where
- China
- Volunteers
- 371 people
- Sponsor
- Vifor (International) Inc.
Iron Deficiency
Safety and Tolerability of BioFe for Iron Deficiency Management
This study evaluates the safety, tolerability, and activity of BioFe in the dietary management of iron deficiency in adults.
- Trial name
- NCT03484026
- Testing
- BioFe
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Sidero Bioscience, LLC
Gastric Cancer, Anemia
Preoperative Intravenous Iron Therapy in Patients With Gastric Cancer
The main objective of this investigator initiated study is to study if preoperative intravenous iron is effective in reducing need for allogenic blood transfusion in patients with gastric cancer who will undergo a standardized…
- Conditions
- Gastric Cancer, Anemia, Surgery, Iron Deficiency Anemia
- Trial name
- IRONSTOMACH (NCT04168346)
- Testing
- Ferric carboxymaltose
- Volunteers
- 202 people
- Sponsor
- Helsinki University Central Hospital
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Chronic Heart Failure, Iron Deficiency
Ferinject® Assessment in Patients With Iron Deficiency and Chronic Heart Failure (FAIR-HF)
This study is designed to evaluate the efficacy of Ferinject® in improving symptoms of CHF in patients with iron deficiency. Analyses will focus both on subjective and objective measures.
- Conditions
- Chronic Heart Failure, Iron Deficiency, Iron Deficiency Anemia, Anaemia
- Trial name
- FAIR-HF (NCT00520780)
- Testing
- Ferinject ® (Ferric carboxymaltose), Normal saline (0.9%)
- Where
- 48 sites in Argentina, Germany and 8 more
- Volunteers
- 456 people
- Sponsor
- Vifor Pharma
Iron-Deficiency Anemia
Ferric Carboxymaltose for Treatment of Anaemia of Cancer in Subjects With Multiple Myeloma Receiving Chemotherapy
Multicentre, randomised, controlled, 2-arm open-label prospective pilot study to evaluate efficacy and safety of ferric carboxymaltose (FCM) in treatment of anaemia in subjects with multiple myeloma (MM) initiating chemotherapy.
- Trial name
- AOC-MM (NCT01100879)
- Testing
- Ferric carboxymaltose
- Where
- 2 sites in France, Greece
- Volunteers
- 3 people
- Sponsor
- Vifor Pharma
Anemia, Iron-Deficiency, Inflammatory Bowel Disease
Safety and Efficacy Study of Oral Ferric Maltol Compared to Intravenous Iron To Treat Iron Deficiency Anaemia in IBD
The purpose of this study is to compare the efficacy of ferric maltol and intravenous iron (IVI) Ferric Carboxy Maltose in the treatment of iron deficiency anaemia (IDA) and subsequent maintenance of haemoglobin in subjects with…
- Conditions
- Anemia, Iron-Deficiency, Inflammatory Bowel Disease, Crohn's Disease
- Trial name
- NCT02680756
- Testing
- Ferric Maltol, Ferric Carboxy Maltose
- Where
- 44 sites in United States, Belgium and 4 more
- Volunteers
- 250 people
- Sponsor
- Shield Therapeutics
Iron Deficiency, Iron Deficiency Anaemia
Assessing the Effect of a Mineral-enriched Powder on Iron Deficiency in Women of Reproductive Age
The goal of this clinical trial is to determine if taking a mineral-enriched powder can raise blood iron levels compared to a placebo powder in reproductive-aged women with iron deficiency.
- Trial name
- NCT05990166
- Testing
- Mineral-enriched powder
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Carleton University
Iron Deficiency
A Study to Collect Data to Build Artificial Intelligence Derived Algorithms for Estimating Iron Status of Children
An exploratory study to collect data to build artificial intelligence derived algorithms for estimating iron status in children
- Trial name
- FERROUS 2 (NCT06577727)
- Testing
- Gold standard blood test, Imaging and videography of anatomical sites
- Where
- 2 sites in Singapore, Thailand
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Iron Deficiency, Infertility
Iron Deficiency as an Ignored Cause of Infertility
Iron deficiency may play a critical role in human infertility, oocyte quality and may even play a role in endometrial receptivity.
- Trial name
- IDI (NCT04510870)
- Testing
- Ferric Carboxymaltose Injection, NaCl infusion
- Where
- Finland
- Volunteers
- 62 people
- Sponsor
- Dextra Fertility Clinic
Iron Deficiency Anemia
Effect of Rice Fortification With Iron on Anemia Among Children
This was a double-blind community-based trial, placebo controlled. During 16 weeks, children in the intervention group (GI, n=180) received iron fortified rice, and children in the control group (GC, n=174) received rice with…
- Trial name
- NCT00727545
- Testing
- iron bisglycine chelate
- Where
- Brazil
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis
A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)
MOMENTUM is a randomized, double-blind, active control Phase 3 trial intended to confirm the differentiated clinical benefits of the investigational drug momelotinib (MMB) versus danazol (DAN) in symptomatic and anemic…
- Conditions
- Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
- Trial name
- NCT04173494
- Testing
- Momelotinib, Danazol
- Where
- 167 sites in United States, Australia and 20 more
- Volunteers
- 195 people
- Sponsor
- Sierra Oncology LLC - a GSK company
Prevalence
Epidemiological Study on Anemia and Iron Deficiency in Pregnancy in Medical Institutions in Some Areas of China
The purpose of this study is to describe the prevalence of anemia and iron deficiency in pregnancy through a multi-center, prospective follow-up study .
- Trial name
- NCT04486456
- Volunteers
- 20,000 people
- Sponsor
- Peking University First Hospital
Postpartum Fatigue, Iron Deficiency Anemia
Maternal Fatigue After Postpartum Anemia Treatment With Intravenous Ferric Carboxymaltose and Oral Iron Therapy
Postpartum Anemia is common after childbirth and may contribute to tiredness and reduced wellbeing in mothers.This randomized controlled trial will compare two treatments for postpartum iron deficiency:intravenous ferric…
- Trial name
- MFI20 (NCT07880314)
- Testing
- INTRAVENOUS FERRIC CARBOXYMALTOSE, oral iron therapy
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Anemia
Iron Dextran Versus Oral Iron for Treating Iron Deficiency Anemia in Pregnant Women
Iron deficiency is the most prevalent nutritional deficiency and the most common cause of anemia .It is characterized by a defect in hemoglobin synthesis, resulting in red blood cells that are abnormally small (microcytic) and…
- Trial name
- NCT03212781
- Testing
- Iron dextran, Ferrous Fumarate
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
CKD
Different Oral Iron Dosing Regimens in Treatment of Iron Deficency Anemia in Patients With Chronic Kidney Disease
Comparing between the efficacy of alternate day oral iron dose, once daily and thrice daily dose in improving anemia in CKD patients
- Trial name
- NCT06521216
- Testing
- Ferrous sulfate
- Volunteers
- 150 people
- Sponsor
- Assiut University
Anemia, Iron Deficiency
Iron Status in Autism Spectrum Disorders
to evaluate the prevalence of iron deficiency anemia in group with autism spectrum disorders in comparison to normal children group
- Trial name
- NCT06441734
- Testing
- cbc serum ferritin serum iron
- Volunteers
- 46 people
- Sponsor
- Assiut University
Iron-deficiency, Iron Deficiency Anemia
Meals to Improve Absorption of Iron Supplements
One of the targeted objectives of Healthy People 2020 is to reduce iron deficiency among women of reproductive age (WRA). Consuming foods rich in iron and/or oral iron supplementation is typically recommended to improve iron…
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency Anemia Treatment
- Trial name
- NCT04793906
- Testing
- Iron supplement with a lunch meal containing beef, Iron supplement with a lunch meal containing plant-based alternative
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Vitamin A Deficiency, Iron-deficiency
Impact of Food-to-Food Fortified Cereal Products on Diet Quality in Rural Niger Villages
The primary hypothesis is that introduction of food-to-food fortified products through a rural Hub-and-Spoke incubator system contributes to an improved food environment and availability of micronutrients to these communities.
- Trial name
- NigerMPS (NCT05893901)
- Where
- Niger
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Purdue University