Clinical trials: Irreversible Pulpitis
Symptomatic Irreversible Pulpitis
Preoperative Acetaminophen- Caffeine- Codeine Combination and Anaesthetic Success in Patients With Acute Pulpitis
The aim of the study is to evaluate the effect of preoperative administration of acetaminophen- codeine -caffeine combination on the success of the inferior alveolar nerve block versus bacetaminophen alone or placebo in patients…
- Trial name
- NCT04202406
- Testing
- Acetaminophen and codeine and caffeine, Acetaminophen
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Aim: The purpose of this prospective, randomized, double-blind, controlled study was to compare the preoperative oral tramadol medication with ibuprofen and acetaminophen on the success of inferior alveolar nerve blocks (IANB) of…
- Trial name
- NCT04961268
- Testing
- TraMADol 50 Mg Oral Tablet, Tramadol 100 MG Oral Tablet, Ibuprofen 600Mg Tab
- Where
- Saudi Arabia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alfarabi Colleges
Pain, Postoperative, Irreversible Pulpitis
Comparison of Nitrofurantoin and Calcium Hydroxide as Intracanal Medicaments in Alleviating Post-operative Pain
Intracanal medicaments have been frequently used in patients with endodontic and periradicular infection for the elimination of microorganisms.
- Trial name
- NCT04900571
- Testing
- Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Irreversible Pulpitis
Partial Pulpotomy in Mature Permanent Teeth With Signs and Symptoms of Irreversible Pulpits
The main purpose of the present study is to assess the outcome of partial pulpotomy by using two different bioactive materials, namely MTA [MTA Angelus (Angelus, Londrina, Brazil) and Total Fill BC putty (FKG, La Chaux-de-Fonds…
- Trial name
- NCT04870398
- Testing
- Vital Pulp therapy-Partial pulpotomy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Irreversible Pulpitis, Reversible Pulpitis
Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy
The optimal treatment of deep caries lesions extended to the inner third of dentin is still under discussion. Cariologists prefer selective caries removal, meanwhile endodontists recommend partial pulpotomy.
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Dentine Caries
- Trial name
- Vitapulp (NCT04807244)
- Testing
- Selective Caries Removal with Biodentine™, Partial Pulpotomy with Biodentine™, Full Pulpotomy with Biodentine™
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Pulpitis - Irreversible
Effectiveness of Mineral Trioxide Aggregate and Platelet Rich Fibrin Along With Biodentine. .
The aim of this study was to clinically and radiographically evaluate the effectiveness of MTA, Biodentine, Platelet Rich Fibrin along with Mineral Trioxide Aggregate and Platelet Rich Fibrin along with Biodentine as pulpotomy…
- Trial name
- NCT04773886
- Testing
- Mineral trioxide aggregate, Biodentine, Platelet rich fibrin
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Irreversible Pulpitis
Pulpotomy as a Treatment of Irreversible Pulpitis
The procedure currently recommended for the treatment of irreversible pulpitis is the endodontic treatment, i.e. the complete elimination of the pulp, disinfection and obturation of the whole root canal system.
- Trial name
- NCT02920606
- Testing
- Pulpotomy, Endodontic treatment
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Irreversible Pulpitis
PRF Pulpotomy Using Different Bioceramic Materials in Permanent Molars
this study aimed to compare the clinical and radiographic outcomes of full pulpotmy after application of Biodentine, or MTA, or Portland cement above PRF membrane In permanent molars with irreversible pulpitis
- Trial name
- NCT04784949
- Testing
- portland cement, Mineral trioxide aggregate, Biodentine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Fayoum University
Pulpitis - Irreversible
Pulpotomy vs.Root Canal Treatment in Managing Irreversible Pulpitis
The study aims to compare two methods of repairing and saving a badly damaged or infected tooth. One method is called root canal treatment (RoCT) and the other (new method) is called pulpotomy.
- Trial name
- NCT03956199
- Testing
- pulpotomy, Root canal treatment
- Where
- 3 sites in United Kingdom
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- King's College London
Symptomatic Irreversible Pulpitis
Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression
To assess the effect of using diclofenac potassium versus prednisolone as a pre-medication compared to placebo on: Intensity of post-endodontic pain in patients with symptomatic irreversible pulpitis. Pulpal IL-8 expression.
- Trial name
- NCT04608981
- Testing
- Prednisolone 30 mg, Diclofenac Potassium 50mg Tab
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Postoperative Pain
Evaluation of Trans-mucosal Bio-adhesive Discs of Diclofenac Potassium on the Anesthetic Success and Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
The aim of the proposed study is to compare the effect of single dose of Diclofenac Potassium premedication as trans-mucosal bio-adhesive discs versus placebo on the effectiveness of the inferior alveolar nerve block and…
- Trial name
- NCT04585438
- Testing
- Diclofenac Potassium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis (Toothache)
Effect of Buffered Numbing Solution on Patients With Toothaches
The purpose of this study is to determine the effect of buffered lidocaine (a numbing solution) on the ability to numb patients with toothaches.
- Trial name
- NCT01868776
- Testing
- buffered lidocaine, nonbuffered lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Irreversible Pulpitis
Comparing the Outcome of Pulpotomy Using Biodentine and Portland Cement in Mature Cases With Irreversible Pulpitis: Randomized Clinical Trial
The aim of the study is to compare the treatment outcome of pulpotomy using Biodentine or Portland cement regarding success rate and post-operative pain.
- Trial name
- NCT04573374
- Testing
- Pulpotomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Residual Dental Pulp Tissue and Cord Blood Stem Cells
The experiments outlined in this proposal are designed to test the hypothesis that the in vivo injection of cord blood stem cells (InvitRx®) into the root canal system will facilitate teeth initially diagnosed with irreversible…
- Trial name
- NCT04040127
- Testing
- Cord blood stem cells, Saline solution
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Symptomatic Irreversible Pulpitis
Comparison Between M-Pro and ProTaper Next
Comparing the postoperative pain resulting after mechanical instrumentation using M-pro files versus that resulting after using ProTaper Next rotary files in lower molar with symptomatic Irreversible pulpitis molars.
- Trial name
- NCT03692039
- Testing
- M-pro files in rotating motion, ProTaper Next files in rotating motion
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Comparative Evaluation of Partial and Complete Pulpotomy in Permanent Molars
This study will compare the outcome of partial pulpotomy and complete pulpotomy in mature permanent molars with clinical signs indicative of irreversible pulpitis
- Trial name
- NCT04397315
- Testing
- Pulpotomy to the level of canal orifices, Pulpotomy up to superficial 2-3 mm of pulp chamber
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Acute Irreversible Pulpitis With Apical Periodontitis
Ketorolac Irrigant on Post Operative Pain
Endodontic post-treatment pain management is one of the most challenging problems in the clinical practice of endodontics. Although this pain is decreased after root canal treatment, there may be residual symptoms due to…
- Trial name
- NCT04319549
- Testing
- Ketorolac Tromethamine irrigant, sodium hypochlorite irrigant
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
MTA vs CEM Pulpotomy in Young Permanent Molars
The aim of the study The purpose of this present clinical study will be to assess : " the successful clinical outcome of CEM cement in comparison to MTA in the pulpotomy of young permanent molar teeth with irreversible pulpitis .
- Trial name
- NCT04243733
- Testing
- CEM and MTA, MTA and CEM
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Symptomatic Irreversible Pulpitis
Occlusal Reduction Effect on Postendodontic Pain
The aim of this study, thus, was to assess the effect of occlusal reduction on postendodontic pain after the first (post-instrumentation) and the second (post-obturation) visit in mandibular posterior teeth with symptomatic…
- Trial name
- NCT04186897
- Testing
- Occlusal reduction
- Volunteers
- 308 people
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Postendodontic Pain on Using Max-i-Probe vs NaviTip as Irrigation Needles
The aim of this prospective, randomized, clinical trial was to evaluate the effect of the side-vented Max-i-Probe versus the end-vented NaviTip as endodontic needles during syringe irrigation on post-operative pain in adult…
- Trial name
- NCT04119661
- Testing
- Max-i-Probe, NaviTip
- Volunteers
- 180 people
- Sponsor
- Cairo University