Clinical trials: Irrigation Activation
Endodontic Disease, Postoperative Pain
Postoperative Pain in Endodontic Therapy
The goal of this clinical trial is to evaluate the change in postoperative pain in mandibular premolar and first molar teeth with asymptomatic apical periodontitis when using EDDY and passive ultrasonic irrigation activation…
- Trial name
- NCT06741592
- Testing
- EDDY Group, PUI Group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ordu University
Antimicrobial Photodynamic Therapy
The Effect of Antimicrobial Photodynamic Therapy on the Success of Root Canal Treatment
The decontamination of the root canal system from pathological microflora is essential for the success of endodontic treatment. Mechanical instrumentation and irrigation solutions, known as the chemomechanical process, are…
- Trial name
- NCT06634745
- Testing
- Standard Needle Irrigation (SNI), Passive Ultrasonic Irrigation (PUI, EndoActivator (EA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Root Canal Treatment, Irrigation Activation
Treatment Outcome and Patient-reported Outcomes in Patient Undergoing Non-surgical Root Canal Treatment With Different Irrigation Protocols
This study aims to evaluate and compare the clinical and patient-reported outcomes of passive ultrasonic irrigation (PUI) and laser-activated irrigation (LAI) versus conventional syringe irrigation in adult patients undergoing…
- Conditions
- Root Canal Treatment, Irrigation Activation, Oral Health Quality of Life (OHQoL) Was Assessed, Post Operative Pain After Root Canal Therapy
- Trial name
- NCT07453134
- Testing
- root canal treatment and intracanal medicament
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Post Operative Pain, Necrotic Mandibular Molars
Postoperative Pain and Periapical Tissue Healing
The success of endodontic treatment derives from the complete elimination of microorganisms capable of causing an intraradicular or extra radicular infection.
- Trial name
- NCT06771570
- Testing
- Silver Nanoparticles Irrigation
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Radwa fath Ahmed
Periapical Periodontitis, Root Canal Infection
The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success
This study evaluates postoperative pain and radiographic healing of asymptomatic posterior teeth with chronic apical periodontitis following root-canal treatment performed using EndoActivator for irrigation activation.
- Trial name
- NCT06339905
- Testing
- Sonic Activation with EndoActivator, Control Needle Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Apical Periodontitis
Comparison of Sonic and Ultrasonic Activation on Healing of Apical Periodontitis
The goal of this clinical trial is to learn whether two different irrigation activation methods - passive ultrasonic irrigation (PUI) and sonic activation - help periapical healing in root canal treatments of single-rooted teeth…
- Trial name
- SONIC-ULTRA (NCT07249450)
- Testing
- Sonic Activation Irrigation, Passive Ultrasonic Irrigation (PUI), Conventional Needle Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hilal Çuhadar Beşiroğlu
Acute Pulpitis With Apical Periodontitis, Postoperative Pain
The Impact Of Different Final Irrigation Activation Techniques On Postoperative Pain
The trial was conducted to assess the impact of passive ultrasonic irrigation, XP endo finisher, AF max file, and manual dynamic agitation on postoperative pain and analgesic consumption at 6 h., 12 h., 24 h., 48 h., 72 h., and a…
- Trial name
- NCT06501703
- Testing
- Instruments
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sinai University
Three Canal Irrigation Methods and Their Comparison, Penetration of Irrigant in the Root Canal
Effectiveness of Three Different Irrigation Methods During a Root Canal Treatment
This study aims to compare the effectiveness of three root canal irrigation techniques-Conventional Needle Irrigation (CNI), Side-Vented Needle (SVN), and Ultrasonic Irrigation (UI)-in achieving irrigant penetration into the…
- Trial name
- NCT07731594
- Testing
- Conventional Needle, Side Vented Needle, Ultrasonic Irrigation
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Post Operative Pain
Evaluation of Post Operative Pain After Sonic Activation and Different Irrigation Needles During Root Canal Treatment
The study compares the post operative pain after root canal therapy, after using different irrigation protocols. The subjects are divided into 3 groups and different irrigation protocol is used in each group.
- Trial name
- Endoactivator (NCT05840783)
- Testing
- Open ended needle irrigation, side vented needle irrigation, Sonic activation
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Periapical Periodontitis, Root Canal Infection
Efficacy of Apical Preparation With Passive Ultrasonic Irrigation in Reducing Intracanal Bacteria
This study evaluates intracanal bacterial load in molar teeth with chronic apical periodontitis before and after root canal shaping with two different apical enlargement sizes and ultrasonic irrigation activation.
- Trial name
- NCT07005219
- Testing
- Root canal shaping with One Curve Mini #25/0.4 and passive ultrasonic irrigation, Root canal shaping with One Curve Mini #35/0.4 and passive ultrasonic irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Retreatment, Asymptomatic Apical Periodontitis
Effects of Irrigation Activation Systems on Postoperative Pain and Lesion Healing in Single-Visit Retreatment
In this superiority randomized clinical trial with a parallel design, 75 asymptomatic maxillary anterior teeth with 2-5 mm periapical lesions and a history of primary root canal treatment (PRCT) at least four years earlier were…
- Trial name
- NCT07150585
- Testing
- Ultrasonic Activation Group, Sonic Activation Group, Laser Activation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ege University
Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis
Effect of Ultrasonic and Diode Laser Activated Irrigation on Postoperative Pain Following Root Canal Treatment
The study is designed to determine whether activation of the irrigant using ultrasonic or diode laser technology can reduce postoperative pain and influence Substance P levels compared with conventional needle irrigation.
- Trial name
- NCT07906808
- Testing
- diode laser activation irrigation, Ultrasonic irrigation activation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- October 6 University
Mandibular Premolars and Canines With Asymptomatic Apical Periodontitis
The Effect of Different Irrigation Methods Used During Endodontic Treatment on Postoperative Pain in Teeth With Periapical Lesions
The aim of this study is to evaluate the effect of different irrigation activation methods used during endodontic treatment on postoperative pain in teeth with periapical lesions, allowing us to clinically determine which…
- Trial name
- NCT07410832
- Testing
- Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Apical Periodontitis, Retreatment
Biomarkers in Apical Periodontitis
Aim: To evaluate the effects of three different irrigation activation techniques-conventional syringe irrigation (CSI), ultrasonic irrigation (UI), and SWEEPS (Shock Wave Enhanced Emission Photoacoustic Streaming)-on the levels…
- Conditions
- Apical Periodontitis, Retreatment, Biomarkers, Cytokine
- Trial name
- NCT07504861
- Testing
- laser activation, PUI, CSI
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Irriversible Pulpitis, Irrigation
Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods
root canal irrigation protocol
- Conditions
- Irriversible Pulpitis, Irrigation, Activation, Patient
- Trial name
- NCT07196215
- Testing
- passive ultrasonic activation, sonic activation
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- RANA AHMAD
Postoperative Pain, Endodontically Treated Teeth
"Effect of Sonic Activation Assisted Irrigation and Apical Enlargement on Postoperative Endodontic Pain"
The purpose of this randomized clinical trial is to evaluate the incidence of postoperative pain after retreatment after apical enlargement and sonic activation assisted irrigation.
- Trial name
- NCT04314908
- Testing
- Apical enlargement, Apical enlargement + Sonic Activation Assisted Irrigation, Non Apical enlargement
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Irrigation Activation
Effect of Different Irrigation Activating Techniques on Irrigant Penetration Depth and on Post-Operative Pain
Irrigation activation in endodontics is considered now a very important step for the success of root canal treatment. In this study, the investigator will examine the effect of two recent activation systems ( XP-endo Finisher…
- Trial name
- NCT05450003
- Testing
- Irrigation activation using xp endo finisher file , new sonic eddy tip and conventional needle syringe irrigation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Irrigation Activation, Endodontic Disease
Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial Reduction
This in-vivo study aim to evaluate effect of different irrigation activating techniques on Irrigant Penetration Depth and Microbial Reduction in root Canals
- Trial name
- NCT06660797
- Testing
- Group1: A matching gutta-percha master cones will be used in up and down motion 2mm amplitude at a frequency of 100 strokes during approximately 1 min in each prepared canal., Group2: XP-endo Finisher activation: The XP-endo Finisher instrument will be used in continuous rotation for 1 mintute, Group 3:EasyClean system activation : EC instrument coupled to the countrangle handpiece and operated with a micromotor at approximately 20,000 rotations per minute in continuous rotation.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University
Root Canal Infection, Periapical; Infection
Bacteria Elimination in Retreatment Cases Using Different Disinfection Techniques
Nonsurgical root canal retreatment may become essential when the initial endodontic treatment fails because of the persistent intracanal or extracanal infections.It has been stated that the one of the main cause of posttreatment…
- Trial name
- NCT03750162
- Testing
- VDW Ultra, AMD picasso, ProtaperNext X3 gutta-percha
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University