Clinical trials: Irritable Bowel Syndrome
Microbial Colonization, Irritable Bowel Syndrome
Probiotic Supplementation in the Dysbiosis of Bowel Preparation
Significant changes in gut microbiota was noted after the high-volume bowel preparation with PEG before colonoscopy. The dynamic changes were found to be short-term.
- Conditions
- Microbial Colonization, Irritable Bowel Syndrome, Metabolic Syndrome
- Trial name
- NCT04774042
- Testing
- Infloran probiotic, HAC probiotic
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Irritable Bowel Syndrome
Evaluation of Treatment Effect of Low FODMAP Diet in Treatment of IBS Patients
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, affecting 15% of the population. IBS is characterized by recurrent abdominal pain/discomfort without identifiable organic lesions.
- Trial name
- NCT05144204
- Testing
- Low FODMAP diet
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Irritable Bowel Syndrome (IBS)
Exercise and Irritable Bowel Syndrome (IBS)
Specific Aim 1: As shown in the literature, exercise can be a useful tool for treating and improving functional GI disorders. Therefore, the aim is to estimate the effectiveness of an exercise intervention on IBS symptoms as…
- Trial name
- AF_IBS (NCT05453084)
- Testing
- Exercise Program
- Where
- Italy
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Irritable Bowel Syndrome
Effect of MethylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule
The investigators plan to measure the local (in vivo) production of hydrogen when methylcellulose is ingested, to see if the investigators can show a shift of the site of fermentation to the distal colon.
- Trial name
- REALISTIC (NCT06551948)
- Testing
- psyllium, methylcellulose, maltodextrin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome, Crohn Disease
Evaluation of the SIMBA Capsule for Small Intestinal Dysbiosis
The SIMBA Capsule is a small, single-use, ingestible capsule that allows for the non-invasive sampling of small bowel contents using purely mechanical means.
- Conditions
- Irritable Bowel Syndrome, Crohn Disease, Celiac Disease, Ulcerative Colitis
- Trial name
- NCT05633706
- Testing
- fluid biopsy capsule
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nimble Science Ltd.
Irritable Bowel Syndrome
Identification of IBS Metabotypes Based on Physiological Responses to Food
Irritable bowel syndrome (IBS) is a condition characterized by abdominal pain, bloating, constipation, diarrhea and gas and affects up to 15% of the Western population.
- Trial name
- NCT03653689
- Testing
- FODMAP, Gluten
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Boswellia Serrata, Irritable Bowel Syndrome
Positive Outcomes of the Supplementation With Lecithin-based Delivery Form of Curcuma Longa and of Boswellia Serrata in IBS
Small bowel dysbiosis (SBD), is a frequent finding in subjects with irritable bowel syndrome (IBS). The formula-tion in sunflower lecithin (Phytosome) of Curcuma longa and Boswellia serrata demonstrated beneficial effects on…
- Trial name
- NCT06407609
- Testing
- Curcuma and boswellia extracts plus low fodmap diet, Low Foodmap diet
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Irritable Bowel Syndrome
Safety and Efficacy Study of PEA and Polydatin on Intestinal Inflammation and Visceral Hyperalgesia in IBS Patients
Despite the pathophysiology of IBS remains largely unsettled, several mechanisms have been proposed to explain symptom generation.
- Trial name
- CMD-IBS09(2) (NCT01370720)
- Testing
- Recoclix
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MARIA CRISTINA COMELLI
Irritable Bowel Syndrome
A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers
This FTIH study is designed to assess the safety, tolerability and pharmacokinetic (PK) of escalating single and repeat oral doses of GSK3352589 in normal healthy volunteers.
- Trial name
- NCT03154086
- Testing
- GSK3352589
- Where
- Australia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Irritable Bowel Syndrome
Small and Large Bowel Transit Tests Using MRI (Study 1)
Irritable bowel syndrome, (IBS) is a common functional disorder of the gut that can be quite disabling to patients. The most common symptoms of IBS are abdominal pain or discomfort along with erratic changes in bowel habit of…
- Trial name
- NCT01534507
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Fibromyalgia, Irritable Bowel Syndrome
Welfare Benefits in Functional Somatic Disorders
The objective of this observational study is to estimate the number of weeks of welfare benefits, i.e. sickness benefit, unemployment benefit and social assistance, for individuals with functional somatic disorders and compare…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT05611606
- Volunteers
- 9,656 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
IBS - Irritable Bowel Syndrome
Study to Evaluate the Efficacy of Poppi Apple Cider Vinegar Prebiotic Soda to Improve Gut Health In Participants
This exploratory observational trial provides the opportunity to gather information on the effect of daily consumption of Poppi Apple Cider Vinegar Prebiotic Soda on gut health and digestion.
- Trial name
- NCT05418439
- Testing
- Drink Poppi Soda
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Drink Poppi
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Irritable Bowel Syndrome
Fecal Amino Acids，Gut Taste Receptors and Irritable Bowel Syndromes
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used to study the amino acid levels…
- Trial name
- NCT06489444
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Microbial Colonization, Gut Microbiota
Diet Supplementation With Prebiotics to Improve Gut Health in Egyptian Children
The study described herein seeks to assess the extent to which diet supplementation of young Egyptian children, one of the most vulnerable groups to the risk of diarrhea, with prebiotic fiber can improve their gut health.
- Trial name
- NCT06561724
- Testing
- Biscuits maltodextrin, Biscuits includes prebiotics tartoufa inulin, Biscuits includes prebiotics chicory inulin
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Primary Headache Disorder
Primary Headaches and Irritable Bowel Syndrome.
To assess the relationship between primary headaches and irritable bowel syndrome
- Trial name
- NCT05057533
- Testing
- a questionnaire based on Rome IV Diagnostic criteria of IBS
- Where
- Egypt
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Assiut University
Irritable Bowel Syndrome
The FAIS-Trial: Faecal Microbiota Transplantation (FMT) in Adolescents With Refractory Irritable Bowel Syndrome (IBS)
A Double-blind randomised placebo-controlled pilot study as well as a reversed translational part To investigate whether two faecal transplantations from either allogeneic (healthy) or autologous (own) donor, administered through…
- Trial name
- FAIS (NCT03074227)
- Testing
- Allogeneic faecal transplantation, Autologous faecal transplantation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Irritable Bowel Syndrome, Healthy
Remote Study of an Electronic Means to Characterize Bowel Movements in Adult Populations
A remote study to find out if a mobile phone application (HealthMode Stool) can serve as a useful tool to track and characterize daily bowel movements.
- Trial name
- NCT04182048
- Where
- United States
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- HealthMode Inc.