Clinical trials: Irritable Bowel Syndrome With Diarrhea
Irritable Bowel Syndrome with Diarrhea, Purine Metabolism Disorder
B.Subtilis Attenuate Symptoms in Diarrhea-predominant Irritable Bowel Syndrome by Increasing Hypoxanthine Biosynthesis
This is a prospective, single-blind, randomized parallel study to investigate whether B. subtilis could improve clinical symptoms of IBS-D patients. Patients are randomly assigned by envelope method.
- Trial name
- NCT06612411
- Testing
- B. subtilis, Dead B. subtilis
- Where
- 2 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Diarrhea
Assessment of Elemental Impurities Level After Multiple Administration of DWJ1230 or DWB2001 in Subjects With Functional Diarrhea or Irritable Bowel Syndrome With Predominant Diarrhea.
This study aims to assess elemental impurities level after dministration of dioctahedral smectite in subjects with functional diarrhea or irritable bowel syndrome with predominant diarrhea.
- Trial name
- NCT05816681
- Testing
- DWJ1230, DWB2001
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Effect of Consuming a Nutraceutical Composition on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome
Irritable bowel syndrome is characterized by the presence of chronic, recurrent abdominal pain, alterations in bowel habits, and abdominal distension. The medical diagnosis is made using the Rome IV criteria.
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed
- Trial name
- NCT07103772
- Testing
- Ananá
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome Mixed
Faecal Microbiota Transplantation in Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is the most common functional bowel disorder, being present in approximately 10% of adult Europoid population. The etiology of IBS is elusive.
- Trial name
- MISCEAT (NCT04899869)
- Testing
- Faecal microbiota transplantation with active study microbiota first, Faecal microbiota transplantation with inactive autoclaved study microbiota first, Faecal microbiota transplantation with inactive autoclaved study microbiota only
- Where
- Czechia
- Volunteers
- 61 people
- Sponsor
- Thomayer University Hospital
Irritable Bowel Syndrome
Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)
The purpose of this study is to determine the efficacy, safety, and tolerability of different doses of eluxadoline (JNJ-27018966) compared with placebo in the treatment of participants with diarrhea-predominant irritable bowel…
- Trial name
- NCT01553747
- Testing
- Eluxadoline
- Where
- 253 sites in United States, Canada and 2 more
- Volunteers
- 1,146 people
- Sponsor
- Furiex Pharmaceuticals, Inc
Irritable Bowel Syndrome
Tritordeum-based Foods for IBS Symptoms
People with irritable bowel syndrome (IBS), especially those with diarrhea (IBS-D), often describe worsening symptoms after eating certain foods.
- Trial name
- TritoinIBS (NCT05307185)
- Testing
- Tritordeum-based food
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Irritable Bowel Syndrome
A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)
This study is designed to evaluate the efficacy and safety of camlipixant in adults with IBS-D and IBS-M. The study has two parts.
- Trial name
- BALANCE (NCT07519395)
- Testing
- Camlipixant
- Where
- 114 sites in United States
- Volunteers
- 420 people
- Sponsor
- GlaxoSmithKline
Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain
Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea
Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects.
- Conditions
- Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain, Functional Magnetic Resonance Imaging, IBS (Irritable Bowel Syndrome)
- Trial name
- NCT06757491
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Irritable Bowel Syndrome With Diarrhea
Therapeutic Effect of Chang'an I Recipe on Irritable Bowel Syndrome With Diarrhea
To evaluate the efficacy and safety of TCM decoction Chang'an I Recipe in the treatment of IBS-D. A multicenter, randomized, double-blind, placebo-controlled clinical trial was designed.
- Trial name
- NCT02822118
- Testing
- Chang'an I Recipe
- Where
- 5 sites in China
- Volunteers
- 216 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation
GOS to Reduce Symptom Severity in IBS
IBS is a highly prevalent bowel disorder, characterized by recurrent abdominal pain during bowel movements or a change in bowel habits.
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome - Constipation, Irritable Bowel Syndrome - Diarrhoea, Irritable Bowel Syndrome - Mixed
- Trial name
- EGIS (NCT05157061)
- Testing
- Galacto-oligosaccharides (GOS), Maltodextrine
- Where
- 9 sites in Belgium, Netherlands and 1 more
- Volunteers
- 153 people
- Sponsor
- Clasado
Patients With Irritable Bowel Syndrome With Diarrhea
Huanghou Zhixie Diwan in the Treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D)
This trial is a randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase II clinical trial. Its purpose is to evaluate the efficacy and safety of Huanghou Zhixie Diwan in subjects with irritable bowel…
- Trial name
- NCT07721012
- Testing
- Huanghou Zhixie Diwan group, Huanghou Zhixie Diwan mimic
- Where
- 14 sites in China
- Volunteers
- 120 people
- Sponsor
- Lei Yunshang Group
Irritable Bowel Syndrome With Diarrhea (IBS-D)
G-PUR® for Symptomatic Treatment in Irritable Bowel Syndrome With Diarrhea
A randomized, double-blind, placebo-controlled pilot study in patients with IBS-D according to Rome IV criteria evaluating the clinical efficacy and safety of oral administration of 2g G-PUR® tid compared to placebo in a cohort…
- Trial name
- NCT04138186
- Testing
- 2.0g G-PUR®, oral administration
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Glock Health, Science and Research GmbH
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Hydrogen Breath Test an Instrument to Predict Rifaximin-Response in Irritable Bowel Syndrome Predominant Diarrhea
The purpose of this study is to learn more about how to improve treatment of patients with diarrhea predominant Irritable Bowel Syndrome (IBS-D) symptoms.Included patients will be requested to answer online surveys and will…
- Trial name
- NCT03729271
- Testing
- Rifaximin, Glucose and lactulose hydrogen breath testing
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- University of Michigan
IBS - Irritable Bowel Syndrome
TReatment of Irritable Bowel Syndrome With Diarrhoea Using Titrated ONdansetron Trial
A placebo controlled study to determine the efficacy and mode of action of ondansetron in the treatment of irritable bowel syndrome with diarrhoea.
- Trial name
- TRITON (NCT03555188)
- Testing
- Ondansetron
- Where
- 14 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Leeds
Irritable Bowel Syndrome With Diarrhea
The Effects of Carbohydrates in Irritable Bowel Syndrome
Food and their components are often reported as gastrointestinal (GI) symptom triggers in patients with IBS. The current interest in dietary management in IBS, has largely focused on the negative effect of poorly absorbed and…
- Trial name
- FIBS (NCT04830410)
- Testing
- Fructan reintroduction
- Where
- Sweden
- Volunteers
- 65 people
- Sponsor
- Sahlgrenska University Hospital
Irritable Bowel Syndrome, Dermatographism
Antihistamines in the Treatment of Irritable Bowel Syndrome With Diarrhea
Irritable bowel syndrome is a functional disorder of the gastrointestinal tract diagnosed with the Rome criteria. The Rome IV criteria are based on abdominal pain symptoms and stool habits including stool frequency and stool…
- Conditions
- Irritable Bowel Syndrome, Dermatographism, Post-prandial Diarrhea
- Trial name
- NCT04612803
- Testing
- Antihistamine
- Where
- United States
- Sponsor
- University of Cincinnati
Ulcerative Colitis, Healthy
GI Permeability Change in Response to Aquamin®
This trial is being completed to learn about how Aquamin® affects gastrointestinal permeability, or the control of material passing from inside the gastrointestinal tract through the gut wall into the rest of the body, in people…
- Conditions
- Ulcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea
- Trial name
- NCT04855799
- Testing
- Aquamin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- James Varani
Digestive Disorders, Irritable Bowel Syndrome
AcuGraph and Digestive Symptoms
This research is designed to study the reliability of the results of an AcuGraph in college students and faculty members with reported digestive symptoms
- Conditions
- Digestive Disorders, Irritable Bowel Syndrome, Constipation, Diarrhea
- Trial name
- NCT00846794
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Irritable Bowel Syndrome With Diarrhea, Effects of Probiotics
Multi Strain Probiotic Preparation in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits without any structural abnormalities.
- Trial name
- NCT04662957
- Testing
- Maltodextrin
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Children's Memorial Health Institute, Poland
Irritable Bowel Syndrome With Diarrhea (IBS-D)
Efficacy, Safety and Tolerability of DNK333 (25 mg Bid) in Women With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)
The purpose of this study is to evaluate the efficacy of DNK333 compared to placebo for relieving symptoms of IBS-D in female patients.
- Trial name
- NCT00394173
- Testing
- DNK333
- Where
- 43 sites in United States, Canada
- Volunteers
- 180 people
- Sponsor
- Novartis