Clinical trials: Irritable Colon
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D)
Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
To evaluate the overall efficacy of repeated Transcranial Magnetic Stimulation(rTMS) combined with a Live Probiotic tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus cereus Tablets, Live) in…
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D), Repetitive Transcranial Magnetic Stimulation (rTMS), Probiotic
- Trial name
- NCT06960369
- Testing
- rTMS combined with Live Probiotic tablet
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Soochow University
Irritable Bowel Syndrome, Colonic Diseases, Functional
fMRI and Visceral Perception Upon Capsaicin Infusion
Brain imaging has shown abnormal brain activations in response to visceral stimulation in patients with the Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD).
- Conditions
- Irritable Bowel Syndrome, Colonic Diseases, Functional, Dyspepsia, Gastrointestinal Diseases
- Trial name
- NCT02551029
- Testing
- Capsaicin
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
IBS-D and Functional Dyspepsia
Trenev Trio/Healthy Trinity for Symptoms of Diarrhea-predominant Irritable Bowel Syndrome (IBS) and Functional Dyspepsia
Primary Objective: To confirm the efficacy of the probiotic product Healthy Trinity (retail label)/Trenev Trio (professional label) in the improvement of symptoms in adult patients with diarrhea-predominant irritable bowel…
- Trial name
- NCT01268618
- Testing
- Probiotic
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sprim Advanced Life Sciences
Irritable Bowel Syndrome
A Clinical Study to Determine the Safety and Efficacy of An Oral Probiotic Supplementation in the Management of Irritable Bowel Syndrome With Protein Digestion.
This is an open-label, two-arm, prospective, interventional, in-use safety and efficacy study of an oral probiotic supplementation in adult subjects having irritable bowel syndrome.
- Trial name
- NCT06687720
- Testing
- MetBroma
- Where
- India
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Irritable Bowel Syndrome
The Effect of Gluten in Patients With Irritable Bowel Syndrome and Healthy Volunteers
Patients with Irritable Bowel Syndrome (IBS) often link their symptoms to foods. Interest in dietary management recently increased, including the use of a gluten-free diet.
- Trial name
- PROT-IBS (NCT03869359)
- Testing
- Gluten-free diet with gluten powder
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Functional Gastrointestinal Disorders, Overlap Syndromes
Overlap FGIDs and Genetic Polymorphism
1. To analyze the prevalence of overlap syndromes among NERD or RH, FD, and IBS patients, and to identify and to compare the differences in their characteristics and symptoms, and to determine their risk factors. 2.
- Trial name
- NCT04712617
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Irritable Bowel Disease
Effects of Fasting and Hydro Colon Therapy Plus Probiotics on GI Microbiota in Intolerances and Irritable Bowel Syndrome
Consequences of Colon Hydrotherapy plus probiotic intervention on composition of GI microbiota and well being are analysed in subjects claiming GI inconveniences due to Irritable Bowel Syndrome or food intolerances.
- Trial name
- MicFFGAH2013 (NCT02372201)
- Testing
- Hydro Colon Therapy plus probiotic
- Where
- Austria
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Irritable Bowel Syndrome
ConfocAl endomicroSCopy bAsed Diet Trial in IBS
After a thorough baseline evaluation, IBS patients will be exposed to nutrients while undergoing confocal laser endomicroscopy (CLE).
- Trial name
- CASCADE (NCT05097872)
- Testing
- Diet
- Where
- Belgium
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders
Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics
The goal of this clinical trial is to test the effectiveness of trimebutine and probiotics in treating Functional Abdominal Pain Disorders (FAPD) in a pediatric population.
- Conditions
- Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Irritable Bowel Syndrome Variant of Childhood
- Trial name
- FAPD_RCT (NCT06268964)
- Testing
- Trimebutine, Lactobacillus rhamnosus
- Where
- Mexico
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Irritable Bowel Syndrome, Abdominal Pain
Comparing a 182mg Colon-targeted-delivery Peppermint Oil Capsule (Tempocol-ColoPulse®) and a 182mg Enteric-coated Peppermint Oil Capsule (Tempocol®), a Pharmacokinetic Study
This is a pilot study to compare the relative bioavailability between two peppermint oil formulations, namely a ileocolonic release peppermint oil and an small intestinal release peppermint oil (Tempocol®).
- Conditions
- Irritable Bowel Syndrome, Abdominal Pain, Colonic Diseases, Visceral Pain
- Trial name
- NCT02291445
- Testing
- Menthae piperitae aetheroleum/peppermint oil (enteric coated capsule), Menthae piperitae aetheroleum/peppermint oil (colon-targeted-delivery capsule)
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Gulf War Illness, Persian Gulf Syndrome
Exercise in Gulf War Illness (GWI)
The purpose of this study is to determine if submaximal exercise by bicycle stress tests with pulmonary measurement of VO2MAX plus maximal isometric hand grips on 2 consecutive days causes a higher level of "exertional…
- Trial name
- NCT01291758
- Testing
- Submaximal bicycle exercise stress tests performed 24 hr apart
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Healthy Subjects, COVID-19 Pneumonia
Jing Si Herbal Tea for Long-Coronavirus Disease(COVID) Gut-brain Interaction
Dyspepsia refers to chronic or recurrent upper gastrointestinal symptoms. According to the Rome IV criteria, functional dyspepsia (FD) symptoms included meal related fullness, early satiation, epigastric pain or burning which are…
- Conditions
- Healthy Subjects, COVID-19 Pneumonia, Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
- Trial name
- NCT05668104
- Testing
- Jing Si Herbal Tea Liquid Packet
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Irritable Bowel Syndrome With Diarrhea
Post-Infectious Irritable Bowel Syndrome (PI-IBS)
Purpose: identification of factors predisposing for Post-Infectious Irritable Bowel Syndrome (PI-IBS) development after an episode of traveler's diarrhea identification of systemic (serum) and local (biopsy) changes in infectious…
- Trial name
- PI-IBS (NCT01497847)
- Where
- Belgium
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Irritable Bowel Syndrome Mixed
The Effect of AI-based Microbiome Diet on IBS-M Symptoms
This study was designed as a pilot, open-labelled study. We enrolled consecutive IBS-M patients (n=25, 19 females, 46.06 ± 13.11 years) according to Rome IV criteria.
- Trial name
- NCT04768387
- Testing
- Personalized microbiome diet
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Gazi University
Microbiota
Stability of the Microbiome in IBD and IBS
In this study the investigators aim to investigate the changes of the intestinal microbiome in three different cohorts (IBD, IBS, healthy) after applying the uniform disruptive factor of osmotic diarrhea induced by macrogol.
- Trial name
- NCT03395548
- Testing
- Macrogol
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Irritable Bowel Syndrome, Tight Junction Alteration
Neurotrophic Factors, Tight Junction Proteins, and Cytokines in IBS
To evaluate the role of neurotrophic factors (NGF, GDNF, TRPV-1), to quantity tight junction proteins (ZO-1, occludin, claudin) and cytokines (IL-8, TNF-a, IL-1b) in the colonic mucosa of IBS patients and also clarify sex…
- Conditions
- Irritable Bowel Syndrome, Tight Junction Alteration, Pathophysiology
- Trial name
- NCT03675100
- Testing
- colonoscopic mucosal biopsy
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Diverticulitis and Irritable Bowel Syndrome
Incidence and Predictive Factor of Irritable Bowel Syndrome After Acute Diverticulitis in Korea
The pathogenesis of irritable bowel syndrome (IBS) is considered immune reaction of gastrointestinal tract. Therefore there is growing evidence that IBS could occur after gastroenteritis.
- Trial name
- NCT02003807
- Where
- South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Digestive Disorders, Irritable Bowel Syndrome
AcuGraph and Digestive Symptoms
This research is designed to study the reliability of the results of an AcuGraph in college students and faculty members with reported digestive symptoms
- Conditions
- Digestive Disorders, Irritable Bowel Syndrome, Constipation, Diarrhea
- Trial name
- NCT00846794
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Healthy
SwissGut - The Healthy Swiss Microbiome
Objective: This study is designed to address the complex interplay between the gut microbiome, environmental factors, and inflammatory diseases, with a specific emphasis on serving as a healthy cohort for several related…
- Trial name
- SwissGut (NCT06191224)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Benjamin Misselwitz